BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 10799490)

  • 1. Hypoxic induction of prolyl 4-hydroxylase alpha (I) in cultured cells.
    Takahashi Y; Takahashi S; Shiga Y; Yoshimi T; Miura T
    J Biol Chem; 2000 May; 275(19):14139-46. PubMed ID: 10799490
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
    Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
    Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation.
    D'Angelo G; Duplan E; Boyer N; Vigne P; Frelin C
    J Biol Chem; 2003 Oct; 278(40):38183-7. PubMed ID: 12876291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation.
    Martin F; Linden T; Katschinski DM; Oehme F; Flamme I; Mukhopadhyay CK; Eckhardt K; Tröger J; Barth S; Camenisch G; Wenger RH
    Blood; 2005 Jun; 105(12):4613-9. PubMed ID: 15741220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.
    Stiehl DP; Wirthner R; Köditz J; Spielmann P; Camenisch G; Wenger RH
    J Biol Chem; 2006 Aug; 281(33):23482-91. PubMed ID: 16790428
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
    Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
    J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
    Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
    J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A conserved family of prolyl-4-hydroxylases that modify HIF.
    Bruick RK; McKnight SL
    Science; 2001 Nov; 294(5545):1337-40. PubMed ID: 11598268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia.
    Berra E; Benizri E; Ginouvès A; Volmat V; Roux D; Pouysségur J
    EMBO J; 2003 Aug; 22(16):4082-90. PubMed ID: 12912907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation.
    Minchenko O; Opentanova I; Minchenko D; Ogura T; Esumi H
    FEBS Lett; 2004 Oct; 576(1-2):14-20. PubMed ID: 15474002
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells.
    Cioffi CL; Liu XQ; Kosinski PA; Garay M; Bowen BR
    Biochem Biophys Res Commun; 2003 Apr; 303(3):947-53. PubMed ID: 12670503
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.
    Huang J; Zhao Q; Mooney SM; Lee FS
    J Biol Chem; 2002 Oct; 277(42):39792-800. PubMed ID: 12181324
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a hypoxia response element in the transferrin receptor gene.
    Lok CN; Ponka P
    J Biol Chem; 1999 Aug; 274(34):24147-52. PubMed ID: 10446188
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning and characterization of a low molecular weight prolyl 4-hydroxylase from Arabidopsis thaliana. Effective hydroxylation of proline-rich, collagen-like, and hypoxia-inducible transcription factor alpha-like peptides.
    Hieta R; Myllyharju J
    J Biol Chem; 2002 Jun; 277(26):23965-71. PubMed ID: 11976332
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor.
    Hirsilä M; Koivunen P; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2003 Aug; 278(33):30772-80. PubMed ID: 12788921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determination and comparison of specific activity of the HIF-prolyl hydroxylases.
    Tuckerman JR; Zhao Y; Hewitson KS; Tian YM; Pugh CW; Ratcliffe PJ; Mole DR
    FEBS Lett; 2004 Oct; 576(1-2):145-50. PubMed ID: 15474027
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclosporin A prevents the hypoxic adaptation by activating hypoxia-inducible factor-1alpha Pro-564 hydroxylation.
    D'Angelo G; Duplan E; Vigne P; Frelin C
    J Biol Chem; 2003 Apr; 278(17):15406-11. PubMed ID: 12586829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
    Jaakkola P; Mole DR; Tian YM; Wilson MI; Gielbert J; Gaskell SJ; von Kriegsheim A; Hebestreit HF; Mukherji M; Schofield CJ; Maxwell PH; Pugh CW; Ratcliffe PJ
    Science; 2001 Apr; 292(5516):468-72. PubMed ID: 11292861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
    Flashman E; Hoffart LM; Hamed RB; Bollinger JM; Krebs C; Schofield CJ
    FEBS J; 2010 Oct; 277(19):4089-99. PubMed ID: 20840591
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.