BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 10801865)

  • 1. Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis.
    Sahin-Tóth M
    J Biol Chem; 2000 Jul; 275(30):22750-5. PubMed ID: 10801865
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hereditary pancreatitis-associated mutation asn(21) --> ile stabilizes rat trypsinogen in vitro.
    Sahin-Tóth M
    J Biol Chem; 1999 Oct; 274(42):29699-704. PubMed ID: 10514442
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trypsinogen stabilization by mutation Arg117-->His: a unifying pathomechanism for hereditary pancreatitis?
    Sahin-Tóth M; Gráf L; Tóth M
    Biochem Biophys Res Commun; 1999 Oct; 264(2):505-8. PubMed ID: 10529393
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative in vitro studies on native and recombinant human cationic trypsins. Cathepsin B is a possible pathological activator of trypsinogen in pancreatitis.
    Szilágyi L; Kénesi E; Katona G; Kaslik G; Juhász G; Gráf L
    J Biol Chem; 2001 Jul; 276(27):24574-80. PubMed ID: 11312265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human cationic trypsinogen. Arg(117) is the reactive site of an inhibitory surface loop that controls spontaneous zymogen activation.
    Kukor Z; Tóth M; Pál G; Sahin-Tóth M
    J Biol Chem; 2002 Feb; 277(8):6111-7. PubMed ID: 11748242
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High-affinity Ca(2+) binding inhibits autoactivation of rat trypsinogen.
    Sahin-Tóth M; Tóth M
    Biochem Biophys Res Commun; 2000 Aug; 275(2):668-71. PubMed ID: 10964720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Significance of trypsinogen gene mutations in the etiology of hereditary pancreatitis].
    Sahin-Tóth M; Tóth M
    Orv Hetil; 2001 Mar; 142(12):603-6. PubMed ID: 11324217
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The tetra-aspartate motif in the activation peptide of human cationic trypsinogen is essential for autoactivation control but not for enteropeptidase recognition.
    Nemoda Z; Sahin-Tóth M
    J Biol Chem; 2005 Aug; 280(33):29645-52. PubMed ID: 15970597
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human anionic trypsinogen: properties of autocatalytic activation and degradation and implications in pancreatic diseases.
    Kukor Z; Tóth M; Sahin-Tóth M
    Eur J Biochem; 2003 May; 270(9):2047-58. PubMed ID: 12709065
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.
    Jancsó Z; Sahin-Tóth M
    J Biol Chem; 2016 Jun; 291(25):12897-905. PubMed ID: 27129265
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction between trypsinogen isoforms in genetically determined pancreatitis: mutation E79K in cationic trypsin (PRSS1) causes increased transactivation of anionic trypsinogen (PRSS2).
    Teich N; Le Maréchal C; Kukor Z; Caca K; Witzigmann H; Chen JM; Tóth M; Mössner J; Keim V; Férec C; Sahin-Tóth M
    Hum Mutat; 2004 Jan; 23(1):22-31. PubMed ID: 14695529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pathobiochemistry of hereditary pancreatitis: studies on recombinant human cationic trypsinogen.
    Sahin-Tóth M
    Pancreatology; 2001; 1(5):461-5. PubMed ID: 12120225
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gain-of-function mutations associated with hereditary pancreatitis enhance autoactivation of human cationic trypsinogen.
    Sahin-Tóth M; Tóth M
    Biochem Biophys Res Commun; 2000 Nov; 278(2):286-9. PubMed ID: 11097832
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.
    Németh BC; Wartmann T; Halangk W; Sahin-Tóth M
    J Biol Chem; 2013 Aug; 288(33):24049-62. PubMed ID: 23814066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hereditary pancreatitis caused by a novel PRSS1 mutation (Arg-122 --> Cys) that alters autoactivation and autodegradation of cationic trypsinogen.
    Simon P; Weiss FU; Sahin-Toth M; Parry M; Nayler O; Lenfers B; Schnekenburger J; Mayerle J; Domschke W; Lerch MM
    J Biol Chem; 2002 Feb; 277(7):5404-10. PubMed ID: 11719509
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chymotrypsin C (caldecrin) stimulates autoactivation of human cationic trypsinogen.
    Nemoda Z; Sahin-Tóth M
    J Biol Chem; 2006 Apr; 281(17):11879-86. PubMed ID: 16505482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activating a zymogen without proteolytic processing: mutation of Lys15 and Asn194 activates trypsinogen.
    Pasternak A; Liu X; Lin TY; Hedstrom L
    Biochemistry; 1998 Nov; 37(46):16201-10. PubMed ID: 9819212
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.
    Szabó A; Sahin-Tóth M
    J Biol Chem; 2012 Jun; 287(24):20701-10. PubMed ID: 22539344
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular pathology and evolutionary and physiological implications of pancreatitis-associated cationic trypsinogen mutations.
    Chen JM; Montier T; Férec C
    Hum Genet; 2001 Sep; 109(3):245-52. PubMed ID: 11702203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cloning and expression of ostrich trypsinogen: an avian trypsin with a highly sensitive autolysis site.
    Szenthe B; Frost C; Szilágyi L; Patthy A; Naudé R; Gráf L
    Biochim Biophys Acta; 2005 Apr; 1748(1):35-42. PubMed ID: 15752690
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.