BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 10802285)

  • 1. Synthesis and GABA(A) receptor activity of 6-oxa-analogs of neurosteroids.
    Nicoletti D; Ghini AA; Furtmüller R; Sieghart W; Dodd RH; Burton G
    Steroids; 2000 Jun; 65(6):349-56. PubMed ID: 10802285
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
    Hawkinson JE; Acosta-Burruel M; Yang KC; Hogenkamp DJ; Chen JS; Lan NC; Drewe JA; Whittemore ER; Woodward RM; Carter RB; Upasani RB
    J Pharmacol Exp Ther; 1998 Oct; 287(1):198-207. PubMed ID: 9765338
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.
    Carter RB; Wood PL; Wieland S; Hawkinson JE; Belelli D; Lambert JJ; White HS; Wolf HH; Mirsadeghi S; Tahir SH; Bolger MB; Lan NC; Gee KW
    J Pharmacol Exp Ther; 1997 Mar; 280(3):1284-95. PubMed ID: 9067315
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors.
    Mehta AK; Ticku MK
    Brain Res; 1998 Sep; 805(1-2):88-94. PubMed ID: 9733930
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.
    Rahman M; Lindblad C; Johansson IM; Bäckström T; Wang MD
    Eur J Pharmacol; 2006 Oct; 547(1-3):37-44. PubMed ID: 16934248
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3Alpha-hydroxy-5alpha-pregnan-20-one levels and GABA(A) receptor-mediated 36Cl(-) flux across development in rat cerebral cortex.
    Grobin AC; Morrow AL
    Brain Res Dev Brain Res; 2001 Nov; 131(1-2):31-9. PubMed ID: 11718833
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The effects of neurosteroids on rat behavior and 3H-muscimol binding in the brain.
    Członkowska AI; Sienkiewicz-Jarosz H; Siemiatkowski M; Bidziński A; Płaźnik A
    Pharmacol Biochem Behav; 1999 Aug; 63(4):639-46. PubMed ID: 10462193
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
    Concas A; Follesa P; Barbaccia ML; Purdy RH; Biggio G
    Eur J Pharmacol; 1999 Jun; 375(1-3):225-35. PubMed ID: 10443579
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neurosteroid modulation of the GABAA receptor in the developing guinea pig cerebral cortex.
    Bailey CD; Brien JF; Reynolds JN
    Brain Res Dev Brain Res; 1999 Mar; 113(1-2):21-8. PubMed ID: 10064870
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Partial agonism by 3alpha,21-dihydroxy-5beta-pregnan-20-one at the gamma-aminobutyric acidA receptor neurosteroid site.
    Xue BG; Whittemore ER; Park CH; Woodward RM; Lan NC; Gee KW
    J Pharmacol Exp Ther; 1997 Jun; 281(3):1095-101. PubMed ID: 9190841
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opposing effects of different steroid sulfates on GABAA receptor-mediated chloride uptake.
    El-Etr M; Akwa Y; Robel P; Baulieu EE
    Brain Res; 1998 Apr; 790(1-2):334-8. PubMed ID: 9593978
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neurosteroid analogues. 10. The effect of methyl group substitution at the C-6 and C-7 positions on the GABA modulatory and anesthetic actions of (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
    Zeng CM; Manion BD; Benz A; Evers AS; Zorumski CF; Mennerick S; Covey DF
    J Med Chem; 2005 Apr; 48(8):3051-9. PubMed ID: 15828844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neurosteroid modulation of [3H]flunitrazepam binding in the medulla: an autoradiographic study.
    Garrett KM; Barron KW; Briscoe RJ; Heesch CM
    Brain Res; 1997 Sep; 768(1-2):301-9. PubMed ID: 9369329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Multiple structural features of steroids mediate subtype-selective effects on human alpha4beta3delta GABAA receptors.
    Pillai GV; Smith AJ; Hunt PA; Simpson PB
    Biochem Pharmacol; 2004 Sep; 68(5):819-31. PubMed ID: 15294445
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.
    Hawkinson JE; Kimbrough CL; Belelli D; Lambert JJ; Purdy RH; Lan NC
    Mol Pharmacol; 1994 Nov; 46(5):977-85. PubMed ID: 7969089
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective actions of certain neuroactive pregnanediols at the gamma-aminobutyric acid type A receptor complex in rat brain.
    McCauley LD; Liu V; Chen JS; Hawkinson JE; Lan NC; Gee KW
    Mol Pharmacol; 1995 Feb; 47(2):354-62. PubMed ID: 7870044
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Radioligand binding studies of caloporoside and novel congeners with contrasting effects upon [35S] TBPS binding to the mammalian GABA(A) receptor.
    Abuhamdah S; Fürstner A; Lees G; Chazot PL
    Biochem Pharmacol; 2005 Nov; 70(9):1382-8. PubMed ID: 16168965
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor.
    Hawkinson JE; Drewe JA; Kimbrough CL; Chen JS; Hogenkamp DJ; Lan NC; Gee KW; Shen KZ; Whittemore ER; Woodward RM
    Mol Pharmacol; 1996 May; 49(5):897-906. PubMed ID: 8622640
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activity of B-nor analogues of neurosteroids on the GABA(A) receptor in primary neuronal cultures.
    Suñol C; García DA; Bujons J; Kristofíková Z; Matyás L; Babot Z; Kasal A
    J Med Chem; 2006 Jun; 49(11):3225-34. PubMed ID: 16722640
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
    Ghiani CA; Tuligi G; Maciocco E; Serra M; Sanna E; Biggio G
    Biochem Pharmacol; 1996 Jun; 51(11):1527-34. PubMed ID: 8630094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.