BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

616 related articles for article (PubMed ID: 10805776)

  • 1. Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure.
    von Bergen M; Friedhoff P; Biernat J; Heberle J; Mandelkow EM; Mandelkow E
    Proc Natl Acad Sci U S A; 2000 May; 97(10):5129-34. PubMed ID: 10805776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. β-Sheet core of tau paired helical filaments revealed by solid-state NMR.
    Daebel V; Chinnathambi S; Biernat J; Schwalbe M; Habenstein B; Loquet A; Akoury E; Tepper K; Müller H; Baldus M; Griesinger C; Zweckstetter M; Mandelkow E; Vijayan V; Lange A
    J Am Chem Soc; 2012 Aug; 134(34):13982-9. PubMed ID: 22862303
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain.
    Barghorn S; Davies P; Mandelkow E
    Biochemistry; 2004 Feb; 43(6):1694-703. PubMed ID: 14769047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments.
    Jeganathan S; von Bergen M; Mandelkow EM; Mandelkow E
    Biochemistry; 2008 Oct; 47(40):10526-39. PubMed ID: 18783251
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tau aggregation is driven by a transition from random coil to beta sheet structure.
    von Bergen M; Barghorn S; Biernat J; Mandelkow EM; Mandelkow E
    Biochim Biophys Acta; 2005 Jan; 1739(2-3):158-66. PubMed ID: 15615635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidized and phosphorylated synthetic peptides corresponding to the second and third tubulin-binding repeats of the tau protein reveal structural features of paired helical filament assembly.
    Hoffmann R; Dawson NF; Wade JD; Otvös L
    J Pept Res; 1997 Aug; 50(2):132-42. PubMed ID: 9273897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis.
    von Bergen M; Barghorn S; Müller SA; Pickhardt M; Biernat J; Mandelkow EM; Davies P; Aebi U; Mandelkow E
    Biochemistry; 2006 May; 45(20):6446-57. PubMed ID: 16700555
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alzheimer's Disease-like Paired Helical Filament Assembly from Truncated Tau Protein Is Independent of Disulfide Crosslinking.
    Al-Hilaly YK; Pollack SJ; Vadukul DM; Citossi F; Rickard JE; Simpson M; Storey JMD; Harrington CR; Wischik CM; Serpell LC
    J Mol Biol; 2017 Nov; 429(23):3650-3665. PubMed ID: 28919235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural studies of tau protein and Alzheimer paired helical filaments show no evidence for beta-structure.
    Schweers O; Schönbrunn-Hanebeck E; Marx A; Mandelkow E
    J Biol Chem; 1994 Sep; 269(39):24290-7. PubMed ID: 7929085
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure.
    von Bergen M; Barghorn S; Li L; Marx A; Biernat J; Mandelkow EM; Mandelkow E
    J Biol Chem; 2001 Dec; 276(51):48165-74. PubMed ID: 11606569
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis.
    Li L; von Bergen M; Mandelkow EM; Mandelkow E
    J Biol Chem; 2002 Nov; 277(44):41390-400. PubMed ID: 12198126
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein anatomy: C-tail region of human tau protein as a crucial structural element in Alzheimer's paired helical filament formation in vitro.
    Yanagawa H; Chung SH; Ogawa Y; Sato K; Shibata-Seki T; Masai J; Ishiguro K
    Biochemistry; 1998 Feb; 37(7):1979-88. PubMed ID: 9485325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding of copper (II) ion to an Alzheimer's tau peptide as revealed by MALDI-TOF MS, CD, and NMR.
    Ma QF; Li YM; Du JT; Kanazawa K; Nemoto T; Nakanishi H; Zhao YF
    Biopolymers; 2005 Oct; 79(2):74-85. PubMed ID: 15986501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conformational transition state is responsible for assembly of microtubule-binding domain of tau protein.
    Hiraoka S; Yao TM; Minoura K; Tomoo K; Sumida M; Taniguchi T; Ishida T
    Biochem Biophys Res Commun; 2004 Mar; 315(3):659-63. PubMed ID: 14975751
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.
    Zheng-Fischhöfer Q; Biernat J; Mandelkow EM; Illenberger S; Godemann R; Mandelkow E
    Eur J Biochem; 1998 Mar; 252(3):542-52. PubMed ID: 9546672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy.
    Sibille N; Sillen A; Leroy A; Wieruszeski JM; Mulloy B; Landrieu I; Lippens G
    Biochemistry; 2006 Oct; 45(41):12560-72. PubMed ID: 17029411
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cryo-EM structures of amyloid-β and tau filaments in Down syndrome.
    Fernandez A; Hoq MR; Hallinan GI; Li D; Bharath SR; Vago FS; Zhang X; Ozcan KA; Newell KL; Garringer HJ; Jiang W; Ghetti B; Vidal R
    Nat Struct Mol Biol; 2024 Jun; 31(6):903-909. PubMed ID: 38553642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C-H ... π interplay between Ile308 and Tyr310 residues in the third repeat of microtubule binding domain is indispensable for self-assembly of three- and four-repeat tau.
    Sogawa K; Okuda R; In Y; Ishida T; Taniguchi T; Minoura K; Tomoo K
    J Biochem; 2012 Sep; 152(3):221-9. PubMed ID: 22659094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Residual structure in the repeat domain of tau: echoes of microtubule binding and paired helical filament formation.
    Eliezer D; Barré P; Kobaslija M; Chan D; Li X; Heend L
    Biochemistry; 2005 Jan; 44(3):1026-36. PubMed ID: 15654759
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain.
    Al-Hilaly YK; Foster BE; Biasetti L; Lutter L; Pollack SJ; Rickard JE; Storey JMD; Harrington CR; Xue WF; Wischik CM; Serpell LC
    FEBS Lett; 2020 Mar; 594(5):944-950. PubMed ID: 31721178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.