207 related articles for article (PubMed ID: 10809231)
1. Identification of Phe313 of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists.
Cui J; Smith RG; Mount GR; Lo JL; Yu J; Walsh TF; Singh SB; DeVita RJ; Goulet MT; Schaeffer JM; Cheng K
Mol Endocrinol; 2000 May; 14(5):671-81. PubMed ID: 10809231
[TBL] [Abstract][Full Text] [Related]
2. Pro7.33(303) of the human GnRH receptor regulates selective binding of mammalian GnRH.
Fromme BJ; Katz AA; Millar RP; Flanagan CA
Mol Cell Endocrinol; 2004 Apr; 219(1-2):47-59. PubMed ID: 15149726
[TBL] [Abstract][Full Text] [Related]
3. Allosteric and orthosteric binding modes of two nonpeptide human gonadotropin-releasing hormone receptor antagonists.
Sullivan SK; Brown MS; Gao Y; Loweth CJ; Lio FM; Crowe PD; Struthers RS; Betz SF
Biochemistry; 2006 Dec; 45(51):15327-37. PubMed ID: 17176055
[TBL] [Abstract][Full Text] [Related]
4. Plasma membrane expression of gonadotropin-releasing hormone receptors: regulation by peptide and nonpeptide antagonists.
Finch AR; Caunt CJ; Armstrong SP; McArdle CA
Mol Endocrinol; 2010 Feb; 24(2):423-35. PubMed ID: 20009083
[TBL] [Abstract][Full Text] [Related]
5. Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor.
Betz SF; Reinhart GJ; Lio FM; Chen C; Struthers RS
J Med Chem; 2006 Jan; 49(2):637-47. PubMed ID: 16420049
[TBL] [Abstract][Full Text] [Related]
6. Structure-function studies of linear and cyclized peptide antagonists of the GnRH receptor.
Beckers T; Bernd M; Kutscher B; Kühne R; Hoffmann S; Reissmann T
Biochem Biophys Res Commun; 2001 Dec; 289(3):653-63. PubMed ID: 11726197
[TBL] [Abstract][Full Text] [Related]
7. Residues within transmembrane helices 2 and 5 of the human gonadotropin-releasing hormone receptor contribute to agonist and antagonist binding.
Hoffmann SH; ter Laak T; Kühne R; Reiländer H; Beckers T
Mol Endocrinol; 2000 Jul; 14(7):1099-115. PubMed ID: 10894158
[TBL] [Abstract][Full Text] [Related]
8. Species selectivity of nonpeptide antagonists of the gonadotropin-releasing hormone receptor is determined by residues in extracellular loops II and III and the amino terminus.
Reinhart GJ; Xie Q; Liu XJ; Zhu YF; Fan J; Chen C; Struthers RS
J Biol Chem; 2004 Aug; 279(33):34115-22. PubMed ID: 15155770
[TBL] [Abstract][Full Text] [Related]
9. Cloning and expression, pharmacological characterization, and internalization kinetics of the pituitary GnRH receptor in a metatherian species of mammal.
King JA; Fidler A; Lawrence S; Adam T; Millar RP; Katz A
Gen Comp Endocrinol; 2000 Mar; 117(3):439-48. PubMed ID: 10764554
[TBL] [Abstract][Full Text] [Related]
10. Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone.
Flanagan CA; Becker II; Davidson JS; Wakefield IK; Zhou W; Sealfon SC; Millar RP
J Biol Chem; 1994 Sep; 269(36):22636-41. PubMed ID: 7915716
[TBL] [Abstract][Full Text] [Related]
11. Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment.
Davidson JS; Assefa D; Pawson A; Davies P; Hapgood J; Becker I; Flanagan C; Roeske R; Millar R
Biochemistry; 1997 Oct; 36(42):12881-9. PubMed ID: 9335546
[TBL] [Abstract][Full Text] [Related]
12. Identification of neutral 4-O-alkyl quinolone nonpeptide GnRH receptor antagonists.
DeVita RJ; Parikh M; Jiang J; Fair JA; Young JR; Walsh TF; Goulet MT; Lo JL; Ren N; Yudkovitz JB; Cui J; Yang YT; Cheng K; Rohrer SP; Wyvratt MJ
Bioorg Med Chem Lett; 2004 Nov; 14(22):5599-603. PubMed ID: 15482932
[TBL] [Abstract][Full Text] [Related]
13. Ala/Thr(201) in extracellular loop 2 and Leu/Phe(290) in transmembrane domain 6 of type 1 frog gonadotropin-releasing hormone receptor confer differential ligand sensitivity and signal transduction.
Seong JY; Wang L; Oh DY; Yun O; Maiti K; Li JH; Soh JM; Choi HS; Kim K; Vaudry H; Kwon HB
Endocrinology; 2003 Feb; 144(2):454-66. PubMed ID: 12538604
[TBL] [Abstract][Full Text] [Related]
14. Determination of the binding mode of thienopyrimidinedione antagonists to the human gonadotropin releasing hormone receptor using structure-activity relationships, site-directed mutagenesis, and homology modeling.
Betz SF; Lio FM; Gao Y; Reinhart GJ; Guo Z; Mesleh MF; Zhu YF; Struthers RS
J Med Chem; 2006 Oct; 49(21):6170-6. PubMed ID: 17034124
[TBL] [Abstract][Full Text] [Related]
15. A new photoreactive antagonist cross-links to the N-terminal domain of the gonadotropin-releasing hormone receptor.
Assefa D; Pawson AJ; McArdle CA; Millar RP; Flanagan CA; Roeske R; Davidson JS
Mol Cell Endocrinol; 1999 Oct; 156(1-2):179-88. PubMed ID: 10612436
[TBL] [Abstract][Full Text] [Related]
16. Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II.
Li JH; Choe H; Wang AF; Maiti K; Wang C; Salam A; Chun SY; Lee WK; Kim K; Kwon HB; Seong JY
Mol Pharmacol; 2005 Apr; 67(4):1099-110. PubMed ID: 15635044
[TBL] [Abstract][Full Text] [Related]
17. Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: role of protein kinase C and activating protein 1.
Cheng KW; Ngan ES; Kang SK; Chow BK; Leung PC
Endocrinology; 2000 Oct; 141(10):3611-22. PubMed ID: 11014215
[TBL] [Abstract][Full Text] [Related]
18. Binding of agonist but not antagonist leads to fluorescence resonance energy transfer between intrinsically fluorescent gonadotropin-releasing hormone receptors.
Horvat RD; Roess DA; Nelson SE; Barisas BG; Clay CM
Mol Endocrinol; 2001 May; 15(5):695-703. PubMed ID: 11328852
[TBL] [Abstract][Full Text] [Related]
19. Expression and function of the gonadotropin-releasing hormone receptor are dependent on a conserved apolar amino acid in the third intracellular loop.
Chung HO; Yang Q; Catt KJ; Arora KK
J Biol Chem; 1999 Dec; 274(50):35756-62. PubMed ID: 10585457
[TBL] [Abstract][Full Text] [Related]
20. Molecular cloning and characterization of a gonadotropin-releasing hormone receptor in the guinea pig, Cavia porcellus.
Fujii Y; Enomoto M; Ikemoto T; Endo D; Okubo K; Aida K; Park MK
Gen Comp Endocrinol; 2004 Apr; 136(2):208-16. PubMed ID: 15028524
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]