BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 10810155)

  • 1. Inversion of the roles of the nucleophile and acid/base catalysts in the covalent binding of epoxyalkyl xyloside inhibitor to the catalytic glutamates of endo-1,4-beta-xylanase (XYNII): a molecular dynamics study.
    Laitinen T; Rouvinen J; Peräkylä M
    Protein Eng; 2000 Apr; 13(4):247-52. PubMed ID: 10810155
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Covalent binding of three epoxyalkyl xylosides to the active site of endo-1,4-xylanase II from Trichoderma reesei.
    Havukainen R; Törrönen A; Laitinen T; Rouvinen J
    Biochemistry; 1996 Jul; 35(29):9617-24. PubMed ID: 8755744
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epoxyalkyl glycosides of D-xylose and xylo-oligosaccharides are active-site markers of xylanases from glycoside hydrolase family 11, not from family 10.
    Ntarima P; Nerinckx W; Klarskov K; Devreese B; Bhat MK; Van Beeumen J; Claeyssens M
    Biochem J; 2000 May; 347 Pt 3(Pt 3):865-73. PubMed ID: 10769193
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural comparison of two major endo-1,4-xylanases from Trichoderma reesei.
    Törrönen A; Rouvinen J
    Biochemistry; 1995 Jan; 34(3):847-56. PubMed ID: 7827044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Three-dimensional structure of endo-1,4-beta-xylanase II from Trichoderma reesei: two conformational states in the active site.
    Törrönen A; Harkki A; Rouvinen J
    EMBO J; 1994 Jun; 13(11):2493-501. PubMed ID: 8013449
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MM-PBSA free energy analysis of endo-1,4-xylanase II (XynII)-substrate complexes: binding of the reactive sugar in a skew boat and chair conformation.
    Laitinen T; Rouvinen J; Peräkylä M
    Org Biomol Chem; 2003 Oct; 1(20):3535-40. PubMed ID: 14599014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A case for reverse protonation: identification of Glu160 as an acid/base catalyst in Thermoanaerobacterium saccharolyticum beta-xylosidase and detailed kinetic analysis of a site-directed mutant.
    Vocadlo DJ; Wicki J; Rupitz K; Withers SG
    Biochemistry; 2002 Aug; 41(31):9736-46. PubMed ID: 12146939
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrogen bonding and catalysis: a novel explanation for how a single amino acid substitution can change the pH optimum of a glycosidase.
    Joshi MD; Sidhu G; Pot I; Brayer GD; Withers SG; McIntosh LP
    J Mol Biol; 2000 May; 299(1):255-79. PubMed ID: 10860737
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystallographic analysis of family 11 endo-beta-1,4-xylanase Xyl1 from Streptomyces sp. S38.
    Wouters J; Georis J; Engher D; Vandenhaute J; Dusart J; Frere JM; Depiereux E; Charlier P
    Acta Crystallogr D Biol Crystallogr; 2001 Dec; 57(Pt 12):1813-9. PubMed ID: 11717493
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional conformational changes of endo-1,4-xylanase II from Trichoderma reesei: a molecular dynamics study.
    Muilu J; Törrönen A; Peräkylä M; Rouvinen J
    Proteins; 1998 Jun; 31(4):434-44. PubMed ID: 9626702
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural and functional properties of low molecular weight endo-1,4-beta-xylanases.
    Törrönen A; Rouvinen J
    J Biotechnol; 1997 Sep; 57(1-3):137-49. PubMed ID: 9335170
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzyme-substrate complex structures of a GH39 beta-xylosidase from Geobacillus stearothermophilus.
    Czjzek M; Ben David A; Bravman T; Shoham G; Henrissat B; Shoham Y
    J Mol Biol; 2005 Nov; 353(4):838-46. PubMed ID: 16212978
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars.
    Notenboom V; Williams SJ; Hoos R; Withers SG; Rose DR
    Biochemistry; 2000 Sep; 39(38):11553-63. PubMed ID: 10995222
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanistic consequences of mutation of active site carboxylates in a retaining beta-1,4-glycanase from Cellulomonas fimi.
    MacLeod AM; Tull D; Rupitz K; Warren RA; Withers SG
    Biochemistry; 1996 Oct; 35(40):13165-72. PubMed ID: 8855954
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Family 39 alpha-l-iduronidases and beta-D-xylosidases react through similar glycosyl-enzyme intermediates: identification of the human iduronidase nucleophile.
    Nieman CE; Wong AW; He S; Clarke L; Hopwood JJ; Withers SG
    Biochemistry; 2003 Jul; 42(26):8054-65. PubMed ID: 12834357
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of the catalytic core of the family F xylanase from Pseudomonas fluorescens and identification of the xylopentaose-binding sites.
    Harris GW; Jenkins JA; Connerton I; Cummings N; Lo Leggio L; Scott M; Hazlewood GP; Laurie JI; Gilbert HJ; Pickersgill RW
    Structure; 1994 Nov; 2(11):1107-16. PubMed ID: 7881909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Catalytic thiol and carboxylate: role of cysteine and glutamic acid in the xylosidic activity of endoxylanase from Chainia sp. (NCL 82-5-1).
    Subray SH; Ameeta RK; Krishna NG; Khan IM
    Arch Biochem Biophys; 1998 Jul; 355(2):153-9. PubMed ID: 9675021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of glu-277 as the catalytic nucleophile of Thermoanaerobacterium saccharolyticum beta-xylosidase using electrospray MS.
    Vocadlo DJ; MacKenzie LF; He S; Zeikus GJ; Withers SG
    Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):449-55. PubMed ID: 9761746
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dissecting the electrostatic interactions and pH-dependent activity of a family 11 glycosidase.
    Joshi MD; Sidhu G; Nielsen JE; Brayer GD; Withers SG; McIntosh LP
    Biochemistry; 2001 Aug; 40(34):10115-39. PubMed ID: 11513590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase.
    Sidhu G; Withers SG; Nguyen NT; McIntosh LP; Ziser L; Brayer GD
    Biochemistry; 1999 Apr; 38(17):5346-54. PubMed ID: 10220321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.