146 related articles for article (PubMed ID: 10819159)
1. Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group.
Lopes F; Moreira R; Iley J
Bioorg Med Chem; 2000 Apr; 8(4):707-16. PubMed ID: 10819159
[TBL] [Abstract][Full Text] [Related]
2. Acyloxymethyl as a drug protecting group. Part 7: Tertiary sulfonamidomethyl ester prodrugs of benzylpenicillin: chemical hydrolysis and anti-bacterial activity.
Iley J; Barroso H; Moreira R; Lopes F; Calheiros T
Bioorg Med Chem; 2000 Jul; 8(7):1629-36. PubMed ID: 10976510
[TBL] [Abstract][Full Text] [Related]
3. Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design.
Rodrigues T; Moreira R; Guedes RC; Iley J; Lopes F
Arch Pharm (Weinheim); 2008 Jun; 341(6):344-50. PubMed ID: 18442019
[TBL] [Abstract][Full Text] [Related]
4. Acyloxymethyl as a drug protecting group: Part 4. The hydrolysis of tertiary amidomethyl ester prodrugs of carboxylic acid agents.
Iley J; Moreira R; Calheiros T; Mendes E
Pharm Res; 1997 Nov; 14(11):1634-9. PubMed ID: 9434286
[TBL] [Abstract][Full Text] [Related]
5. Bioreversible quaternary N-acyloxymethyl derivatives of the tertiary amines bupivacaine and lidocaine--synthesis, aqueous solubility and stability in buffer, human plasma and simulated intestinal fluid.
Nielsen AB; Buur A; Larsen C
Eur J Pharm Sci; 2005 Apr; 24(5):433-40. PubMed ID: 15784333
[TBL] [Abstract][Full Text] [Related]
6. Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents.
Mendes E; Furtado T; Neres J; Iley J; Jarvinen T; Rautio J; Moreira R
Bioorg Med Chem; 2002 Mar; 10(3):809-16. PubMed ID: 11814870
[TBL] [Abstract][Full Text] [Related]
7. Acyloxymethyl as a drug protecting group. Part 3. Tertiary O-amidomethyl esters of penicillin G: chemical hydrolysis and anti-bacterial activity.
Moreira R; Calheiros T; Cabrita J; Mendes E; Pimentel M; Iley J
Pharm Res; 1996 Jan; 13(1):70-5. PubMed ID: 8668682
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, chemical and enzymatic hydrolysis, and bioavailability evaluation in rabbits of metronidazole amino acid ester prodrugs with enhanced water solubility.
Mahfouz NM; Hassan MA
J Pharm Pharmacol; 2001 Jun; 53(6):841-8. PubMed ID: 11428660
[TBL] [Abstract][Full Text] [Related]
9. Prodrugs of peptides. 11. Chemical and enzymatic hydrolysis kinetics of N-acyloxymethyl derivatives of a peptide-like bond.
Bundgaard H; Rasmussen GJ
Pharm Res; 1991 Oct; 8(10):1238-42. PubMed ID: 1796040
[TBL] [Abstract][Full Text] [Related]
10. Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug.
Rautio J; Vernerová M; Aufderhaar I; Huttunen KM
Bioorg Med Chem Lett; 2014 Nov; 24(21):5034-6. PubMed ID: 25248681
[TBL] [Abstract][Full Text] [Related]
11. Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes.
Carvalho E; Francisco AP; Iley J; Rosa E
Bioorg Med Chem; 2000 Jul; 8(7):1719-25. PubMed ID: 10976519
[TBL] [Abstract][Full Text] [Related]
12. Carbamate ester prodrugs of dopaminergic compounds: synthesis, stability, and bioconversion.
Hansen KT; Faarup P; Bundgaard H
J Pharm Sci; 1991 Aug; 80(8):793-8. PubMed ID: 1686464
[TBL] [Abstract][Full Text] [Related]
13. Prodrug forms for the sulfonamide group. IV. Kinetics of hydrolysis of N-sulfonyl pseudourea derivatives.
Larsen JD; Bundgaard H
Acta Pharm Nord; 1989; 1(1):31-40. PubMed ID: 2597336
[TBL] [Abstract][Full Text] [Related]
14. Stability studies of some glycolamide ester prodrugs of niflumic acid in aqueous buffers and human plasma by HPLC with UV detection.
Talath S; Shirote PJ; Lough WJ; Gadad AK
Arzneimittelforschung; 2006; 56(9):631-9. PubMed ID: 17063638
[TBL] [Abstract][Full Text] [Related]
15. pH-dependent general base catalyzed activation rather than isocyanate liberation may explain the superior anticancer efficacy of laromustine compared to related 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine prodrugs.
Penketh PG; Finch RA; Sauro R; Baumann RP; Ratner ES; Shyam K
Chem Biol Drug Des; 2018 Jan; 91(1):62-74. PubMed ID: 28636806
[TBL] [Abstract][Full Text] [Related]
16. Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo evaluation.
Tammara VK; Narurkar MM; Crider AM; Khan MA
J Pharm Sci; 1994 May; 83(5):644-8. PubMed ID: 8071813
[TBL] [Abstract][Full Text] [Related]
17. In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor.
Sunkara G; Deruiter J; Clark CR; Kompella UB
J Pharm Pharmacol; 2000 Sep; 52(9):1113-22. PubMed ID: 11045892
[TBL] [Abstract][Full Text] [Related]
18. Isosorbide-based aspirin prodrugs. II. Hydrolysis kinetics of isosorbide diaspirinate.
Gilmer JF; Moriarty LM; Lally MN; Clancy JM
Eur J Pharm Sci; 2002 Sep; 16(4-5):297-304. PubMed ID: 12208460
[TBL] [Abstract][Full Text] [Related]
19. Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media.
Ribeiro L; Silva N; Iley J; Rautio J; Järvinen T; Mota-Filipe H; Moreira R; Mendes E
Arch Pharm (Weinheim); 2007 Jan; 340(1):32-40. PubMed ID: 17206608
[TBL] [Abstract][Full Text] [Related]
20. Aqueous solubility and dissolution rate does not adequately predict in vivo performance: a probe utilizing some N-acyloxymethyl phenytoin prodrugs.
Stella VJ; Martodihardjo S; Rao VM
J Pharm Sci; 1999 Aug; 88(8):775-9. PubMed ID: 10430541
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]