BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 10819159)

  • 1. Acyloxymethyl as a drug protecting group. Part 6: N-acyloxymethyl- and N-[(aminocarbonyloxy)methyl]sulfonamides as prodrugs of agents containing a secondary sulfonamide group.
    Lopes F; Moreira R; Iley J
    Bioorg Med Chem; 2000 Apr; 8(4):707-16. PubMed ID: 10819159
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acyloxymethyl as a drug protecting group. Part 7: Tertiary sulfonamidomethyl ester prodrugs of benzylpenicillin: chemical hydrolysis and anti-bacterial activity.
    Iley J; Barroso H; Moreira R; Lopes F; Calheiros T
    Bioorg Med Chem; 2000 Jul; 8(7):1629-36. PubMed ID: 10976510
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unanticipated acyloxymethylation of sumatriptan indole nitrogen atom and its implications in prodrug design.
    Rodrigues T; Moreira R; Guedes RC; Iley J; Lopes F
    Arch Pharm (Weinheim); 2008 Jun; 341(6):344-50. PubMed ID: 18442019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acyloxymethyl as a drug protecting group: Part 4. The hydrolysis of tertiary amidomethyl ester prodrugs of carboxylic acid agents.
    Iley J; Moreira R; Calheiros T; Mendes E
    Pharm Res; 1997 Nov; 14(11):1634-9. PubMed ID: 9434286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bioreversible quaternary N-acyloxymethyl derivatives of the tertiary amines bupivacaine and lidocaine--synthesis, aqueous solubility and stability in buffer, human plasma and simulated intestinal fluid.
    Nielsen AB; Buur A; Larsen C
    Eur J Pharm Sci; 2005 Apr; 24(5):433-40. PubMed ID: 15784333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, stability and in vitro dermal evaluation of aminocarbonyloxymethyl esters as prodrugs of carboxylic acid agents.
    Mendes E; Furtado T; Neres J; Iley J; Jarvinen T; Rautio J; Moreira R
    Bioorg Med Chem; 2002 Mar; 10(3):809-16. PubMed ID: 11814870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Acyloxymethyl as a drug protecting group. Part 3. Tertiary O-amidomethyl esters of penicillin G: chemical hydrolysis and anti-bacterial activity.
    Moreira R; Calheiros T; Cabrita J; Mendes E; Pimentel M; Iley J
    Pharm Res; 1996 Jan; 13(1):70-5. PubMed ID: 8668682
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, chemical and enzymatic hydrolysis, and bioavailability evaluation in rabbits of metronidazole amino acid ester prodrugs with enhanced water solubility.
    Mahfouz NM; Hassan MA
    J Pharm Pharmacol; 2001 Jun; 53(6):841-8. PubMed ID: 11428660
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prodrugs of peptides. 11. Chemical and enzymatic hydrolysis kinetics of N-acyloxymethyl derivatives of a peptide-like bond.
    Bundgaard H; Rasmussen GJ
    Pharm Res; 1991 Oct; 8(10):1238-42. PubMed ID: 1796040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutathione-S-transferase selective release of metformin from its sulfonamide prodrug.
    Rautio J; Vernerová M; Aufderhaar I; Huttunen KM
    Bioorg Med Chem Lett; 2014 Nov; 24(21):5034-6. PubMed ID: 25248681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Triazene drug metabolites. Part 17: Synthesis and plasma hydrolysis of acyloxymethyl carbamate derivatives of antitumour triazenes.
    Carvalho E; Francisco AP; Iley J; Rosa E
    Bioorg Med Chem; 2000 Jul; 8(7):1719-25. PubMed ID: 10976519
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Carbamate ester prodrugs of dopaminergic compounds: synthesis, stability, and bioconversion.
    Hansen KT; Faarup P; Bundgaard H
    J Pharm Sci; 1991 Aug; 80(8):793-8. PubMed ID: 1686464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prodrug forms for the sulfonamide group. IV. Kinetics of hydrolysis of N-sulfonyl pseudourea derivatives.
    Larsen JD; Bundgaard H
    Acta Pharm Nord; 1989; 1(1):31-40. PubMed ID: 2597336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stability studies of some glycolamide ester prodrugs of niflumic acid in aqueous buffers and human plasma by HPLC with UV detection.
    Talath S; Shirote PJ; Lough WJ; Gadad AK
    Arzneimittelforschung; 2006; 56(9):631-9. PubMed ID: 17063638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. pH-dependent general base catalyzed activation rather than isocyanate liberation may explain the superior anticancer efficacy of laromustine compared to related 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine prodrugs.
    Penketh PG; Finch RA; Sauro R; Baumann RP; Ratner ES; Shyam K
    Chem Biol Drug Des; 2018 Jan; 91(1):62-74. PubMed ID: 28636806
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo evaluation.
    Tammara VK; Narurkar MM; Crider AM; Khan MA
    J Pharm Sci; 1994 May; 83(5):644-8. PubMed ID: 8071813
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor.
    Sunkara G; Deruiter J; Clark CR; Kompella UB
    J Pharm Pharmacol; 2000 Sep; 52(9):1113-22. PubMed ID: 11045892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isosorbide-based aspirin prodrugs. II. Hydrolysis kinetics of isosorbide diaspirinate.
    Gilmer JF; Moriarty LM; Lally MN; Clancy JM
    Eur J Pharm Sci; 2002 Sep; 16(4-5):297-304. PubMed ID: 12208460
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aminocarbonyloxymethyl ester prodrugs of flufenamic acid and diclofenac: suppressing the rearrangement pathway in aqueous media.
    Ribeiro L; Silva N; Iley J; Rautio J; Järvinen T; Mota-Filipe H; Moreira R; Mendes E
    Arch Pharm (Weinheim); 2007 Jan; 340(1):32-40. PubMed ID: 17206608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aqueous solubility and dissolution rate does not adequately predict in vivo performance: a probe utilizing some N-acyloxymethyl phenytoin prodrugs.
    Stella VJ; Martodihardjo S; Rao VM
    J Pharm Sci; 1999 Aug; 88(8):775-9. PubMed ID: 10430541
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.