443 related articles for article (PubMed ID: 10833458)
1. Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.
Sujay Subbayya IN; Sukumaran S; Shivashankar K; Balaram H
Biochem Biophys Res Commun; 2000 Jun; 272(2):596-602. PubMed ID: 10833458
[TBL] [Abstract][Full Text] [Related]
2. Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Munagala NR; Wang CC
Biochemistry; 1998 Nov; 37(47):16612-9. PubMed ID: 9843428
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.
Gayathri P; Sujay Subbayya IN; Ashok CS; Selvi TS; Balaram H; Murthy MR
Proteins; 2008 Dec; 73(4):1010-20. PubMed ID: 18536021
[TBL] [Abstract][Full Text] [Related]
4. Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.
Ullman B; Cyr N; Choi K; Jardim A
Int J Biochem Cell Biol; 2010 Feb; 42(2):253-62. PubMed ID: 19861168
[TBL] [Abstract][Full Text] [Related]
5. A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity.
Raman J; Sumathy K; Anand RP; Balaram H
Arch Biochem Biophys; 2004 Jul; 427(1):116-22. PubMed ID: 15178494
[TBL] [Abstract][Full Text] [Related]
6. Kinetic mechanism of human hypoxanthine-guanine phosphoribosyltransferase: rapid phosphoribosyl transfer chemistry.
Xu Y; Eads J; Sacchettini JC; Grubmeyer C
Biochemistry; 1997 Mar; 36(12):3700-12. PubMed ID: 9132023
[TBL] [Abstract][Full Text] [Related]
7. Evidence for multiple active states of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Sujay Subbayya IN; Balaram H
Biochem Biophys Res Commun; 2000 Dec; 279(2):433-7. PubMed ID: 11118304
[TBL] [Abstract][Full Text] [Related]
8. Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase. Stability studies on the product-activated enzyme.
Raman J; Ashok CS; Subbayya SI; Anand RP; Selvi ST; Balaram H
FEBS J; 2005 Apr; 272(8):1900-11. PubMed ID: 15819884
[TBL] [Abstract][Full Text] [Related]
9. A single amino acid substitution in the human and a bacterial hypoxanthine phosphoribosyltransferase modulates specificity for the binding of guanine.
Lee CC; Craig SP; Eakin AE
Biochemistry; 1998 Mar; 37(10):3491-8. PubMed ID: 9521670
[TBL] [Abstract][Full Text] [Related]
10. Development of a bacterial screen for novel hypoxanthine-guanine phosphoribosyltransferase substrates.
Shivashankar K; Subbayya IN; Balaram H
J Mol Microbiol Biotechnol; 2001 Oct; 3(4):557-62. PubMed ID: 11545274
[TBL] [Abstract][Full Text] [Related]
11. Catalysis in human hypoxanthine-guanine phosphoribosyltransferase: Asp 137 acts as a general acid/base.
Xu Y; Grubmeyer C
Biochemistry; 1998 Mar; 37(12):4114-24. PubMed ID: 9521733
[TBL] [Abstract][Full Text] [Related]
12. Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate.
Gogia S; Balaram H; Puranik M
Biochemistry; 2011 May; 50(19):4184-93. PubMed ID: 21486037
[TBL] [Abstract][Full Text] [Related]
13. The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle.
Keough DT; Brereton IM; de Jersey J; Guddat LW
J Mol Biol; 2005 Aug; 351(1):170-81. PubMed ID: 15990111
[TBL] [Abstract][Full Text] [Related]
14. Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1.
Welin M; Egeblad L; Johansson A; Stenmark P; Wang L; Flodin S; Nyman T; Trésaugues L; Kotenyova T; Johansson I; Eriksson S; Eklund H; Nordlund P
FEBS J; 2010 Dec; 277(23):4920-30. PubMed ID: 21054786
[TBL] [Abstract][Full Text] [Related]
15. Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.
Chen Q; Liang Y; Su X; Gu X; Zheng X; Luo M
J Mol Biol; 2005 May; 348(5):1199-210. PubMed ID: 15854655
[TBL] [Abstract][Full Text] [Related]
16. Steady-state kinetics of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus: the role of threonine-47.
Munagala NR; Chin MS; Wang CC
Biochemistry; 1998 Mar; 37(12):4045-51. PubMed ID: 9521725
[TBL] [Abstract][Full Text] [Related]
17. A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis.
Subbayya IN; Balaram H
FEBS Lett; 2002 Jun; 521(1-3):72-6. PubMed ID: 12067729
[TBL] [Abstract][Full Text] [Related]
18. Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase: a target for anti-malarial chemotherapy.
Keough DT; Hocková D; Krecmerová M; Cesnek M; Holý A; Naesens L; Brereton IM; Winzor DJ; de Jersey J; Guddat LW
Mol Biochem Parasitol; 2010 Oct; 173(2):165-9. PubMed ID: 20595032
[TBL] [Abstract][Full Text] [Related]
19. [Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis].
You DL; Qu H; Chen Q; Xing Y; Gu XC; Luo M
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai); 2003 Sep; 35(9):853-8. PubMed ID: 12958660
[TBL] [Abstract][Full Text] [Related]
20. Understanding substrate specificity in human and parasite phosphoribosyltransferases through calculation and experiment.
Pitera JW; Munagala NR; Wang CC; Kollman PA
Biochemistry; 1999 Aug; 38(32):10298-306. PubMed ID: 10441123
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
