426 related articles for article (PubMed ID: 10837010)
1. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Frandsen H; Alexander J
Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
[TBL] [Abstract][Full Text] [Related]
2. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Malfatti MA; Connors MS; Mauthe RJ; Felton JS
Cancer Res; 1996 Jun; 56(11):2550-5. PubMed ID: 8653696
[TBL] [Abstract][Full Text] [Related]
3. 2-Amino-1-methyl-6-(5-hydroxy-)phenylimidazo[4,5-b]pyridine (5-OH-PhIP), a biomarker for the genotoxic dose of the heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Frandsen H; Frederiksen H; Alexander J
Food Chem Toxicol; 2002 Aug; 40(8):1125-30. PubMed ID: 12067574
[TBL] [Abstract][Full Text] [Related]
4. Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate--biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Frandsen H
Food Chem Toxicol; 2007 May; 45(5):863-70. PubMed ID: 17184892
[TBL] [Abstract][Full Text] [Related]
5. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
[TBL] [Abstract][Full Text] [Related]
6. Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4, 5-f]quinoline.
Agus C; Ilett KF; Kadlubar FF; Minchin RF
Carcinogenesis; 2000 Jun; 21(6):1213-9. PubMed ID: 10837012
[TBL] [Abstract][Full Text] [Related]
7. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
[TBL] [Abstract][Full Text] [Related]
8. Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice.
Lin DX; Lang NP; Kadlubar FF
Drug Metab Dispos; 1995 Apr; 23(4):518-24. PubMed ID: 7600922
[TBL] [Abstract][Full Text] [Related]
9. Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans.
Stillwell WG; Sinha R; Tannenbaum SR
Carcinogenesis; 2002 May; 23(5):831-8. PubMed ID: 12016157
[TBL] [Abstract][Full Text] [Related]
10. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
King RS; Teitel CH; Kadlubar FF
Carcinogenesis; 2000 Jul; 21(7):1347-54. PubMed ID: 10874013
[TBL] [Abstract][Full Text] [Related]
11. Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
Kadlubar F; Kaderlik RK; Mulder GJ; Lin D; Butler MA; Teitel CH; Minchin RF; Ilett KF; Friesen MD; Bartsch H
Princess Takamatsu Symp; 1995; 23():207-13. PubMed ID: 8844812
[TBL] [Abstract][Full Text] [Related]
12. Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.
Teunissen SF; Vlaming ML; Rosing H; Schellens JH; Schinkel AH; Beijnen JH
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Sep; 878(25):2353-62. PubMed ID: 20708442
[TBL] [Abstract][Full Text] [Related]
13. Urinary N2-(2'-deoxyguanosin-8-yl)PhIP as a biomarker for PhIP exposure.
Fang M; Edwards RJ; Bartlet-Jones M; Taylor GW; Murray S; Boobis AR
Carcinogenesis; 2004 Jun; 25(6):1053-62. PubMed ID: 14742322
[TBL] [Abstract][Full Text] [Related]
14. Activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) to mutagenic metabolites.
Buonarati MH; Felton JS
Carcinogenesis; 1990 Jul; 11(7):1133-8. PubMed ID: 2197012
[TBL] [Abstract][Full Text] [Related]
15. Biomonitoring of dietary heterocyclic amines and metabolites in urine by liquid phase microextraction: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a possible biomarker of exposure to dietary PhIP.
Busquets R; Frandsen H; Jönsson JÅ; Puignou L; Galceran MT; Skog K
Chem Res Toxicol; 2013 Feb; 26(2):233-40. PubMed ID: 23276304
[TBL] [Abstract][Full Text] [Related]
16. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland.
Sadrieh N; Davis CD; Snyderwine EG
Cancer Res; 1996 Jun; 56(12):2683-7. PubMed ID: 8665493
[TBL] [Abstract][Full Text] [Related]
17. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ; Devanaboyina US; Doll MA; Zhao S; Xiao GH; Hein DW
Toxicol Sci; 2003 Aug; 74(2):253-9. PubMed ID: 12773763
[TBL] [Abstract][Full Text] [Related]
18. Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.
Wang Y; Peng L; Bellamri M; Langouët S; Turesky RJ
Chem Res Toxicol; 2015 May; 28(5):1045-59. PubMed ID: 25815793
[TBL] [Abstract][Full Text] [Related]
19. Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by data-dependent tandem mass spectrometry.
Peng L; Dasari S; Tabb DL; Turesky RJ
Chem Res Toxicol; 2012 Oct; 25(10):2179-93. PubMed ID: 22827630
[TBL] [Abstract][Full Text] [Related]
20. Enhanced glutathione S-transferase expression in 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-resistant IEC-18 cells.
Teubner W; Fuchs JI; Steinberg P
Cell Biol Toxicol; 2007 May; 23(3):153-61. PubMed ID: 17122891
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
