These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

416 related articles for article (PubMed ID: 10837010)

  • 1. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Frandsen H; Alexander J
    Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Malfatti MA; Connors MS; Mauthe RJ; Felton JS
    Cancer Res; 1996 Jun; 56(11):2550-5. PubMed ID: 8653696
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 2-Amino-1-methyl-6-(5-hydroxy-)phenylimidazo[4,5-b]pyridine (5-OH-PhIP), a biomarker for the genotoxic dose of the heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
    Frandsen H; Frederiksen H; Alexander J
    Food Chem Toxicol; 2002 Aug; 40(8):1125-30. PubMed ID: 12067574
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deconjugation of N-glucuronide conjugated metabolites with hydrazine hydrate--biomarkers for exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
    Frandsen H
    Food Chem Toxicol; 2007 May; 45(5):863-70. PubMed ID: 17184892
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
    Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of an ATP-dependent pathway of activation for the heterocyclic amine carcinogen N-hydroxy-2-amino-3-methylimidazo[4, 5-f]quinoline.
    Agus C; Ilett KF; Kadlubar FF; Minchin RF
    Carcinogenesis; 2000 Jun; 21(6):1213-9. PubMed ID: 10837012
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
    Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
    Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice.
    Lin DX; Lang NP; Kadlubar FF
    Drug Metab Dispos; 1995 Apr; 23(4):518-24. PubMed ID: 7600922
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Excretion of the N(2)-glucuronide conjugate of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in urine and its relationship to CYP1A2 and NAT2 activity levels in humans.
    Stillwell WG; Sinha R; Tannenbaum SR
    Carcinogenesis; 2002 May; 23(5):831-8. PubMed ID: 12016157
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
    King RS; Teitel CH; Kadlubar FF
    Carcinogenesis; 2000 Jul; 21(7):1347-54. PubMed ID: 10874013
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic activation and DNA adduct detection of PhIP in dogs, rats, and humans in relation to urinary bladder and colon carcinogenesis.
    Kadlubar F; Kaderlik RK; Mulder GJ; Lin D; Butler MA; Teitel CH; Minchin RF; Ilett KF; Friesen MD; Bartsch H
    Princess Takamatsu Symp; 1995; 23():207-13. PubMed ID: 8844812
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development and validation of a liquid chromatography-tandem mass spectrometry assay for the analysis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its metabolite 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in plasma, urine, bile, intestinal contents, faeces and eight selected tissues from mice.
    Teunissen SF; Vlaming ML; Rosing H; Schellens JH; Schinkel AH; Beijnen JH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 Sep; 878(25):2353-62. PubMed ID: 20708442
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Urinary N2-(2'-deoxyguanosin-8-yl)PhIP as a biomarker for PhIP exposure.
    Fang M; Edwards RJ; Bartlet-Jones M; Taylor GW; Murray S; Boobis AR
    Carcinogenesis; 2004 Jun; 25(6):1053-62. PubMed ID: 14742322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) to mutagenic metabolites.
    Buonarati MH; Felton JS
    Carcinogenesis; 1990 Jul; 11(7):1133-8. PubMed ID: 2197012
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biomonitoring of dietary heterocyclic amines and metabolites in urine by liquid phase microextraction: 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a possible biomarker of exposure to dietary PhIP.
    Busquets R; Frandsen H; Jönsson JÅ; Puignou L; Galceran MT; Skog K
    Chem Res Toxicol; 2013 Feb; 26(2):233-40. PubMed ID: 23276304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland.
    Sadrieh N; Davis CD; Snyderwine EG
    Cancer Res; 1996 Jun; 56(12):2683-7. PubMed ID: 8665493
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
    Fretland AJ; Devanaboyina US; Doll MA; Zhao S; Xiao GH; Hein DW
    Toxicol Sci; 2003 Aug; 74(2):253-9. PubMed ID: 12773763
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mass Spectrometric Characterization of Human Serum Albumin Adducts Formed with N-Oxidized Metabolites of 2-Amino-1-methylphenylimidazo[4,5-b]pyridine in Human Plasma and Hepatocytes.
    Wang Y; Peng L; Bellamri M; Langouët S; Turesky RJ
    Chem Res Toxicol; 2015 May; 28(5):1045-59. PubMed ID: 25815793
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mapping serum albumin adducts of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by data-dependent tandem mass spectrometry.
    Peng L; Dasari S; Tabb DL; Turesky RJ
    Chem Res Toxicol; 2012 Oct; 25(10):2179-93. PubMed ID: 22827630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced glutathione S-transferase expression in 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-resistant IEC-18 cells.
    Teubner W; Fuchs JI; Steinberg P
    Cell Biol Toxicol; 2007 May; 23(3):153-61. PubMed ID: 17122891
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.