BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

231 related articles for article (PubMed ID: 10837014)

  • 1. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH-cytochrome P450 reductase.
    Kushida H; Fujita K; Suzuki A; Yamada M; Endo T; Nohmi T; Kamataki T
    Carcinogenesis; 2000 Jun; 21(6):1227-32. PubMed ID: 10837014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase.
    Fujita K; Kamataki T
    Mutat Res; 2001 Nov; 483(1-2):35-41. PubMed ID: 11600130
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Development of a Salmonella tester strain sensitive to promutagenic N-nitrosamines: expression of recombinant CYP2A6 and human NADPH-cytochrome P450 reductase in S. typhimurium YG7108.
    Kushida H; Fujita K; Suzuki A; Yamada M; Nohmi T; Kamataki T
    Mutat Res; 2000 Nov; 471(1-2):135-43. PubMed ID: 11080669
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase.
    Fujita K; Kamataki T
    Environ Mol Mutagen; 2001; 38(4):339-46. PubMed ID: 11774366
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic polymorphism of CYP2A6 in relation to cancer.
    Kamataki T; Nunoya K; Sakai Y; Kushida H; Fujita K
    Mutat Res; 1999 Jul; 428(1-2):125-30. PubMed ID: 10517986
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP.
    Kamataki T; Fujita K; Nakayama K; Yamazaki Y; Miyamoto M; Ariyoshi N
    Drug Metab Rev; 2002 Aug; 34(3):667-76. PubMed ID: 12214673
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450 mediated biotransformation.
    Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
    Mutagenesis; 2005 Mar; 20(2):93-100. PubMed ID: 15728263
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
    Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Construction of Salmonella typhimurium YG7108 strains, each coexpressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase.
    Fujita K; Nakayama K; Yamazaki Y; Tsuruma K; Yamada M; Nohmi T; Kamataki T
    Environ Mol Mutagen; 2001; 38(4):329-38. PubMed ID: 11774365
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Competitive interactions between cytochromes P450 2A6 and 2E1 for NADPH-cytochrome P450 oxidoreductase in the microsomal membranes produced by a baculovirus expression system.
    Tan Y; Patten CJ; Smith T; Yang CS
    Arch Biochem Biophys; 1997 Jun; 342(1):82-91. PubMed ID: 9185616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans.
    Camus AM; Geneste O; Honkakoski P; Béréziat JC; Henderson CJ; Wolf CR; Bartsch H; Lang MA
    Mol Carcinog; 1993; 7(4):268-75. PubMed ID: 8352885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93-100).
    Duarte MP; Palma BB; Gilep AA; Laires A; Oliveira JS; Usanov SA; Rueff J; Kranendonk M
    Mutagenesis; 2007 Jan; 22(1):75-81. PubMed ID: 17158518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutagenic activation of betel quid-specific N-nitrosamines catalyzed by human cytochrome P450 coexpressed with NADPH-cytochrome P450 reductase in Salmonella typhimurium YG7108.
    Miyazaki M; Sugawara E; Yoshimura T; Yamazaki H; Kamataki T
    Mutat Res; 2005 Mar; 581(1-2):165-71. PubMed ID: 15725615
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylamine to products genotoxic in an acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H; Oda Y; Funae Y; Imaoka S; Inui Y; Guengerich FP; Shimada T
    Carcinogenesis; 1992 Jun; 13(6):979-85. PubMed ID: 1600620
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of chemopreventive effects of 8-methoxypsoralen against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced mouse lung adenomas.
    Miyazaki M; Yamazaki H; Takeuchi H; Saoo K; Yokohira M; Masumura K; Nohmi T; Funae Y; Imaida K; Kamataki T
    Carcinogenesis; 2005 Nov; 26(11):1947-55. PubMed ID: 15958517
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): mutational specificity in the gpt gene of AS52 cells.
    Tiano HF; Wang RL; Hosokawa M; Crespi C; Tindall KR; Langenbach R
    Carcinogenesis; 1994 Dec; 15(12):2859-66. PubMed ID: 8001247
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cytochrome b(5) coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium.
    Cooper MT; Porter TD
    Mutat Res; 2001 Dec; 484(1-2):61-8. PubMed ID: 11733072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Establishment of ten strains of genetically engineered Salmonella typhimurium TA1538 each co-expressing a form of human cytochrome P450 with NADPH-cytochrome P450 reductase sensitive to various promutagens.
    Yamazaki Y; Fujita K; Nakayama K; Suzuki A; Nakamura K; Yamazaki H; Kamataki T
    Mutat Res; 2004 Aug; 562(1-2):151-62. PubMed ID: 15279838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5.
    Emmert B; Bünger J; Keuch K; Müller M; Emmert S; Hallier E; Westphal GA
    Toxicology; 2006 Nov; 228(1):66-76. PubMed ID: 16978761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the CYP isozyme profile induced by cyclohexanol.
    Espinosa-Aguirre JJ; Rubio J; López I; Nosti R; Asteinza J
    Mutagenesis; 1997 May; 12(3):159-62. PubMed ID: 9175641
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.