BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 10837373)

  • 1. Polycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21.
    Nakanishi Y; Pei XH; Takayama K; Bai F; Izumi M; Kimotsuki K; Inoue K; Minami T; Wataya H; Hara N
    Am J Respir Cell Mol Biol; 2000 Jun; 22(6):747-54. PubMed ID: 10837373
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mdm2 and bax, downstream mediators of the p53 response, are degraded by the ubiquitin-proteasome pathway.
    Chang YC; Lee YS; Tejima T; Tanaka K; Omura S; Heintz NH; Mitsui Y; Magae J
    Cell Growth Differ; 1998 Jan; 9(1):79-84. PubMed ID: 9438391
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of the aromatic hydrocarbon receptor pathway is not sufficient for transcriptional repression of BRCA-1: requirements for metabolism of benzo[a]pyrene to 7r,8t-dihydroxy-9t,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Jeffy BD; Chirnomas RB; Chen EJ; Gudas JM; Romagnolo DF
    Cancer Res; 2002 Jan; 62(1):113-21. PubMed ID: 11782367
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 gene family p51(p63)-encoded, secondary transactivator p51B(TAp63alpha) occurs without forming an immunoprecipitable complex with MDM2, but responds to genotoxic stress by accumulation.
    Okada Y; Osada M; Kurata S; Sato S; Aisaki K; Kageyama Y; Kihara K; Ikawa Y; Katoh I
    Exp Cell Res; 2002 Jun; 276(2):194-200. PubMed ID: 12027449
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteasome-dependent regulation of p21WAF1/CIP1 expression.
    Blagosklonny MV; Wu GS; Omura S; el-Deiry WS
    Biochem Biophys Res Commun; 1996 Oct; 227(2):564-9. PubMed ID: 8878553
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.
    Qiao D; Gaitonde SV; Qi W; Martinez JD
    Carcinogenesis; 2001 Jun; 22(6):957-64. PubMed ID: 11375905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Stabilization of p53 by adenovirus E1A occurs through its amino-terminal region by modification of the ubiquitin-proteasome pathway.
    Nakajima T; Morita K; Tsunoda H; Imajoh-Ohmi S; Tanaka H; Yasuda H; Oda K
    J Biol Chem; 1998 Aug; 273(32):20036-45. PubMed ID: 9685342
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation.
    Rodriguez MS; Desterro JM; Lain S; Lane DP; Hay RT
    Mol Cell Biol; 2000 Nov; 20(22):8458-67. PubMed ID: 11046142
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo ubiquitination and proteasome-mediated degradation of p53(1).
    Maki CG; Huibregtse JM; Howley PM
    Cancer Res; 1996 Jun; 56(11):2649-54. PubMed ID: 8653711
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53.
    Zhang Z; Wang H; Li M; Agrawal S; Chen X; Zhang R
    J Biol Chem; 2004 Apr; 279(16):16000-6. PubMed ID: 14761977
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
    Yang YM; Conaway CC; Chiao JW; Wang CX; Amin S; Whysner J; Dai W; Reinhardt J; Chung FL
    Cancer Res; 2002 Jan; 62(1):2-7. PubMed ID: 11782348
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The p53-Mdm2 module and the ubiquitin system.
    Michael D; Oren M
    Semin Cancer Biol; 2003 Feb; 13(1):49-58. PubMed ID: 12507556
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of p53 stability by Mdm2.
    Kubbutat MH; Jones SN; Vousden KH
    Nature; 1997 May; 387(6630):299-303. PubMed ID: 9153396
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
    Campomenosi P; Monti P; Aprile A; Abbondandolo A; Frebourg T; Gold B; Crook T; Inga A; Resnick MA; Iggo R; Fronza G
    Oncogene; 2001 Jun; 20(27):3573-9. PubMed ID: 11429705
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
    Jin Y; Lee H; Zeng SX; Dai MS; Lu H
    EMBO J; 2003 Dec; 22(23):6365-77. PubMed ID: 14633995
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.
    Xirodimas D; Saville MK; Edling C; Lane DP; Laín S
    Oncogene; 2001 Aug; 20(36):4972-83. PubMed ID: 11526482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aberrant p21 regulation in radioresistant primary glioblastoma multiforme cells bearing wild-type p53.
    Kraus A; Gross MW; Knuechel R; Münkel K; Neff F; Schlegel J
    J Neurosurg; 2000 Nov; 93(5):863-72. PubMed ID: 11059670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TNF-alpha induced p21(WAF1) but not Bax in colon cancer cells WiDr with mutated p53: important role of protein stabilization.
    Kobayashi N; Takada Y; Hachiya M; Ando K; Nakajima N; Akashi M
    Cytokine; 2000 Dec; 12(12):1745-54. PubMed ID: 11097743
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Knocking down PML impairs p53 signaling transduction pathway and suppresses irradiation induced apoptosis in breast carcinoma cell MCF-7.
    Bao-Lei T; Zhu-Zhong M; Yi S; Jun-Jie Q; Yan D; Hua L; Bin L; Guo-Wei Z; Zhi-Xian S
    J Cell Biochem; 2006 Feb; 97(3):561-71. PubMed ID: 16215989
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Promoter specificity and stability control of the p53-related protein p73.
    Lee CW; La Thangue NB
    Oncogene; 1999 Jul; 18(29):4171-81. PubMed ID: 10435630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.