BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 10842179)

  • 1. Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74.
    Rosenkilde MM; Kledal TN; Holst PJ; Schwartz TW
    J Biol Chem; 2000 Aug; 275(34):26309-15. PubMed ID: 10842179
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activation of murine herpesvirus 68- and Kaposi's sarcoma-associated herpesvirus-encoded ORF74 G protein-coupled receptors by human and murine chemokines.
    Verzijl D; Fitzsimons CP; Van Dijk M; Stewart JP; Timmerman H; Smit MJ; Leurs R
    J Virol; 2004 Apr; 78(7):3343-51. PubMed ID: 15016856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways.
    Smit MJ; Verzijl D; Casarosa P; Navis M; Timmerman H; Leurs R
    J Virol; 2002 Feb; 76(4):1744-52. PubMed ID: 11799169
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Virally encoded 7TM receptors.
    Rosenkilde MM; Waldhoer M; Lüttichau HR; Schwartz TW
    Oncogene; 2001 Mar; 20(13):1582-93. PubMed ID: 11313905
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Helix 8 of the viral chemokine receptor ORF74 directs chemokine binding.
    Verzijl D; Pardo L; van Dijk M; Gruijthuijsen YK; Jongejan A; Timmerman H; Nicholas J; Schwarz M; Murphy PM; Leurs R; Smit MJ
    J Biol Chem; 2006 Nov; 281(46):35327-35. PubMed ID: 16997914
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis.
    Pati S; Cavrois M; Guo HG; Foulke JS; Kim J; Feldman RA; Reitz M
    J Virol; 2001 Sep; 75(18):8660-73. PubMed ID: 11507211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Viral G Protein-Coupled Receptor ORF74 Hijacks β-Arrestins for Endocytic Trafficking in Response to Human Chemokines.
    de Munnik SM; Kooistra AJ; van Offenbeek J; Nijmeijer S; de Graaf C; Smit MJ; Leurs R; Vischer HF
    PLoS One; 2015; 10(4):e0124486. PubMed ID: 25894435
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The viral G protein-coupled receptor ORF74 unmasks phospholipase C signaling of the receptor tyrosine kinase IGF-1R.
    de Munnik SM; van der Lee R; Velders DM; van Offenbeek J; Smits-de Vries L; Leurs R; Smit MJ; Vischer HF
    Cell Signal; 2016 Jun; 28(6):595-605. PubMed ID: 26931381
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse.
    Guo HG; Sadowska M; Reid W; Tschachler E; Hayward G; Reitz M
    J Virol; 2003 Feb; 77(4):2631-9. PubMed ID: 12552002
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74.
    Rosenkilde MM; Kledal TN; Bräuner-Osborne H; Schwartz TW
    J Biol Chem; 1999 Jan; 274(2):956-61. PubMed ID: 9873037
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Charged residues at the intracellular boundary of transmembrane helices 2 and 3 independently affect constitutive activity of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.
    Ho HH; Ganeshalingam N; Rosenhouse-Dantsker A; Osman R; Gershengorn MC
    J Biol Chem; 2001 Jan; 276(2):1376-82. PubMed ID: 11031271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis.
    Waldhoer M; Casarosa P; Rosenkilde MM; Smit MJ; Leurs R; Whistler JL; Schwartz TW
    J Biol Chem; 2003 May; 278(21):19473-82. PubMed ID: 12646575
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3.
    Rosenkilde MM; Kledal TN; Schwartz TW
    Mol Pharmacol; 2005 Jul; 68(1):11-9. PubMed ID: 15788740
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A G protein-coupled receptor encoded by rhesus rhadinovirus is similar to ORF74 of Kaposi's sarcoma-associated herpesvirus.
    Estep RD; Axthelm MK; Wong SW
    J Virol; 2003 Feb; 77(3):1738-46. PubMed ID: 12525607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins.
    Rosenkilde MM; McLean KA; Holst PJ; Schwartz TW
    J Biol Chem; 2004 Jul; 279(31):32524-33. PubMed ID: 15155729
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The N terminus of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor is necessary for high affinity chemokine binding but not for constitutive activity.
    Ho HH; Du D; Gershengorn MC
    J Biol Chem; 1999 Oct; 274(44):31327-32. PubMed ID: 10531332
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity.
    Holst PJ; Rosenkilde MM; Manfra D; Chen SC; Wiekowski MT; Holst B; Cifire F; Lipp M; Schwartz TW; Lira SA
    J Clin Invest; 2001 Dec; 108(12):1789-96. PubMed ID: 11748262
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Patterns of gene expression and a transactivation function exhibited by the vGCR (ORF74) chemokine receptor protein of Kaposi's sarcoma-associated herpesvirus.
    Chiou CJ; Poole LJ; Kim PS; Ciufo DM; Cannon JS; ap Rhys CM; Alcendor DJ; Zong JC; Ambinder RF; Hayward GS
    J Virol; 2002 Apr; 76(7):3421-39. PubMed ID: 11884567
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74.
    McLean KA; Holst PJ; Martini L; Schwartz TW; Rosenkilde MM
    Virology; 2004 Aug; 325(2):241-51. PubMed ID: 15246264
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kaposi's sarcoma-associated herpesvirus (KSHV) chemokine vMIP-II and human SDF-1alpha inhibit signaling by KSHV G protein-coupled receptor.
    Geras-Raaka E; Varma A; Clark-Lewis I; Gershengorn MC
    Biochem Biophys Res Commun; 1998 Dec; 253(3):725-7. PubMed ID: 9918794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.