BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 10842342)

  • 21. Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA.
    Skarzynski T; Kim DH; Lees WJ; Walsh CT; Duncan K
    Biochemistry; 1998 Feb; 37(8):2572-7. PubMed ID: 9485407
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin.
    Olesen SH; Ingles DJ; Yang Y; Schönbrunn E
    J Basic Microbiol; 2014 Apr; 54(4):322-6. PubMed ID: 23686727
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin.
    Schönbrunn E; Sack S; Eschenburg S; Perrakis A; Krekel F; Amrhein N; Mandelkow E
    Structure; 1996 Sep; 4(9):1065-75. PubMed ID: 8805592
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Evidence that the reaction of the UDP-N-acetylglucosamine 1-carboxyvinyltransferase proceeds through the O-phosphothioketal of pyruvic acid bound to Cys115 of the enzyme.
    Wanke C; Amrhein N
    Eur J Biochem; 1993 Dec; 218(3):861-70. PubMed ID: 8281938
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp.
    Jiang S; Gilpin ME; Attia M; Ting YL; Berti PJ
    Biochemistry; 2011 Mar; 50(12):2205-12. PubMed ID: 21294548
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural basis for the interaction of the fluorescence probe 8-anilino-1-naphthalene sulfonate (ANS) with the antibiotic target MurA.
    Schonbrunn E; Eschenburg S; Luger K; Kabsch W; Amrhein N
    Proc Natl Acad Sci U S A; 2000 Jun; 97(12):6345-9. PubMed ID: 10823915
    [TBL] [Abstract][Full Text] [Related]  

  • 27. UDP-N-Acetylglucosamine enolpyruvyl transferase (MurA) of Acinetobacter baumannii (AbMurA): Structural and functional properties.
    Sonkar A; Shukla H; Shukla R; Kalita J; Pandey T; Tripathi T
    Int J Biol Macromol; 2017 Apr; 97():106-114. PubMed ID: 28064057
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Inhibition of the MurA enzyme in Fusobacterium nucleatum by potential inhibitors identified through computational and in vitro approaches.
    Kumar A; Saranathan R; Prashanth K; Tiwary BK; Krishna R
    Mol Biosyst; 2017 May; 13(5):939-954. PubMed ID: 28358152
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Thermodynamic characterization of ligand-induced conformational changes in UDP-N-acetylglucosamine enolpyruvyl transferase.
    Samland AK; Jelesarov I; Kuhn R; Amrhein N; Macheroux P
    Biochemistry; 2001 Aug; 40(33):9950-6. PubMed ID: 11502190
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Crystallization and preliminary X-ray diffraction analysis of UDP-N-acetylglucosamine enolpyruvyltransferase of Enterobacter cloacae.
    Sack S; Dauter Z; Wanke C; Amrhein N; Mandelkow E; Schönbrunn E
    J Struct Biol; 1996; 117(1):73-6. PubMed ID: 8776890
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Comprehensive structural and functional characterization of Mycobacterium tuberculosis UDP-NAG enolpyruvyl transferase (Mtb-MurA) and prediction of its accurate binding affinities with inhibitors.
    Babajan B; Chaitanya M; Rajsekhar C; Gowsia D; Madhusudhana P; Naveen M; Chitta SK; Anuradha CM
    Interdiscip Sci; 2011 Sep; 3(3):204-16. PubMed ID: 21956743
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibitory mechanism of the Qβ lysis protein A2.
    Reed CA; Langlais C; Kuznetsov V; Young R
    Mol Microbiol; 2012 Nov; 86(4):836-44. PubMed ID: 22934834
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of a novel fosfomycin-resistant UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) from a soil metagenome.
    Cheng G; Hu Y; Lu N; Li J; Wang Z; Chen Q; Zhu B
    Biotechnol Lett; 2013 Feb; 35(2):273-8. PubMed ID: 23143172
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Catalytic Mechanism and Covalent Inhibition of UDP-
    Mihalovits LM; Ferenczy GG; Keserű GM
    J Chem Inf Model; 2019 Dec; 59(12):5161-5173. PubMed ID: 31715096
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.
    Okada K; Hirotsu K; Hayashi H; Kagamiyama H
    Biochemistry; 2001 Jun; 40(25):7453-63. PubMed ID: 11412098
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structures of Qβ virions, virus-like particles, and the Qβ-MurA complex reveal internal coat proteins and the mechanism of host lysis.
    Cui Z; Gorzelnik KV; Chang JY; Langlais C; Jakana J; Young R; Zhang J
    Proc Natl Acad Sci U S A; 2017 Oct; 114(44):11697-11702. PubMed ID: 29078304
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Farnesyltransferase--new insights into the zinc-coordination sphere paradigm: evidence for a carboxylate-shift mechanism.
    Sousa SF; Fernandes PA; Ramos MJ
    Biophys J; 2005 Jan; 88(1):483-94. PubMed ID: 15501930
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes.
    Lokanath NK; Pampa KJ; Takio K; Kunishima N
    J Mol Biol; 2008 Jan; 375(4):1013-25. PubMed ID: 18062990
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure and mechanism of the genomically encoded fosfomycin resistance protein, FosX, from Listeria monocytogenes.
    Fillgrove KL; Pakhomova S; Schaab MR; Newcomer ME; Armstrong RN
    Biochemistry; 2007 Jul; 46(27):8110-20. PubMed ID: 17567049
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state.
    Mayer ML; Olson R; Gouaux E
    J Mol Biol; 2001 Aug; 311(4):815-36. PubMed ID: 11518533
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.