149 related articles for article (PubMed ID: 10864928)
1. Location of the glucuronosyltransferase domain in the heparan sulfate copolymerase EXT1 by analysis of Chinese hamster ovary cell mutants.
Wei G; Bai X; Gabb MM; Bame KJ; Koshy TI; Spear PG; Esko JD
J Biol Chem; 2000 Sep; 275(36):27733-40. PubMed ID: 10864928
[TBL] [Abstract][Full Text] [Related]
2. Etiological point mutations in the hereditary multiple exostoses gene EXT1: a functional analysis of heparan sulfate polymerase activity.
Cheung PK; McCormick C; Crawford BE; Esko JD; Tufaro F; Duncan G
Am J Hum Genet; 2001 Jul; 69(1):55-66. PubMed ID: 11391482
[TBL] [Abstract][Full Text] [Related]
3. Biosynthesis of heparin/heparan sulfate. Identification of a 70-kDa protein catalyzing both the D-glucuronosyl- and the N-acetyl-D-glucosaminyltransferase reactions.
Lind T; Lindahl U; Lidholt K
J Biol Chem; 1993 Oct; 268(28):20705-8. PubMed ID: 8407890
[TBL] [Abstract][Full Text] [Related]
4. The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate.
Lind T; Tufaro F; McCormick C; Lindahl U; Lidholt K
J Biol Chem; 1998 Oct; 273(41):26265-8. PubMed ID: 9756849
[TBL] [Abstract][Full Text] [Related]
5. The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis.
Senay C; Lind T; Muguruma K; Tone Y; Kitagawa H; Sugahara K; Lidholt K; Lindahl U; Kusche-Gullberg M
EMBO Rep; 2000 Sep; 1(3):282-6. PubMed ID: 11256613
[TBL] [Abstract][Full Text] [Related]
6. Hereditary multiple exostoses and heparan sulfate polymerization.
Zak BM; Crawford BE; Esko JD
Biochim Biophys Acta; 2002 Dec; 1573(3):346-55. PubMed ID: 12417417
[TBL] [Abstract][Full Text] [Related]
7. The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.
McCormick C; Duncan G; Goutsos KT; Tufaro F
Proc Natl Acad Sci U S A; 2000 Jan; 97(2):668-73. PubMed ID: 10639137
[TBL] [Abstract][Full Text] [Related]
8. Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.
Busse M; Feta A; Presto J; Wilén M; Grønning M; Kjellén L; Kusche-Gullberg M
J Biol Chem; 2007 Nov; 282(45):32802-10. PubMed ID: 17761672
[TBL] [Abstract][Full Text] [Related]
9. Biosynthesis of heparan sulfate in EXT1-deficient cells.
Okada M; Nadanaka S; Shoji N; Tamura J; Kitagawa H
Biochem J; 2010 May; 428(3):463-71. PubMed ID: 20377530
[TBL] [Abstract][Full Text] [Related]
10. Accumulation of a pentasaccharide terminating in alpha-N-acetylglucosamine in an animal cell mutant defective in heparan sulfate biosynthesis.
Zhang L; Esko JD
J Biol Chem; 1995 May; 270(21):12557-62. PubMed ID: 7759502
[TBL] [Abstract][Full Text] [Related]
11. Haploinsufficiency of EXT1 and Heparan Sulphate Deficiency Associated with Hereditary Multiple Exostoses in a Pakistani Family.
Ajmal M; Muhammad H; Nasir M; Shoaib M; Malik SA; Ullah I
Medicina (Kaunas); 2022 Dec; 59(1):. PubMed ID: 36676722
[No Abstract] [Full Text] [Related]
12. Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.
Aikawa J; Esko JD
J Biol Chem; 1999 Jan; 274(5):2690-5. PubMed ID: 9915799
[TBL] [Abstract][Full Text] [Related]
13. A single mutation affects both N-acetylglucosaminyltransferase and glucuronosyltransferase activities in a Chinese hamster ovary cell mutant defective in heparan sulfate biosynthesis.
Lidholt K; Weinke JL; Kiser CS; Lugemwa FN; Bame KJ; Cheifetz S; Massagué J; Lindahl U; Esko JD
Proc Natl Acad Sci U S A; 1992 Mar; 89(6):2267-71. PubMed ID: 1532254
[TBL] [Abstract][Full Text] [Related]
14. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
[TBL] [Abstract][Full Text] [Related]
15. The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.
Kitagawa H; Shimakawa H; Sugahara K
J Biol Chem; 1999 May; 274(20):13933-7. PubMed ID: 10318803
[TBL] [Abstract][Full Text] [Related]
16. In vitro polymerization of heparan sulfate backbone by the EXT proteins.
Busse M; Kusche-Gullberg M
J Biol Chem; 2003 Oct; 278(42):41333-7. PubMed ID: 12907669
[TBL] [Abstract][Full Text] [Related]
17. Loss of function in heparan sulfate elongation genes EXT1 and EXT 2 results in improved nitric oxide bioavailability and endothelial function.
Mooij HL; Cabrales P; Bernelot Moens SJ; Xu D; Udayappan SD; Tsai AG; van der Sande MA; de Groot E; Intaglietta M; Kastelein JJ; Dallinga-Thie GM; Esko JD; Stroes ES; Nieuwdorp M
J Am Heart Assoc; 2014 Dec; 3(6):e001274. PubMed ID: 25468659
[TBL] [Abstract][Full Text] [Related]
18. Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
Kim BT; Kitagawa H; Tamura J; Saito T; Kusche-Gullberg M; Lindahl U; Sugahara K
Proc Natl Acad Sci U S A; 2001 Jun; 98(13):7176-81. PubMed ID: 11390981
[TBL] [Abstract][Full Text] [Related]
19. Glucuronyltransferase activity of KfiC from Escherichia coli strain K5 requires association of KfiA: KfiC and KfiA are essential enzymes for production of K5 polysaccharide, N-acetylheparosan.
Sugiura N; Baba Y; Kawaguchi Y; Iwatani T; Suzuki K; Kusakabe T; Yamagishi K; Kimata K; Kakuta Y; Watanabe H
J Biol Chem; 2010 Jan; 285(3):1597-606. PubMed ID: 19915003
[TBL] [Abstract][Full Text] [Related]
20. Association of EXT1 and EXT2, hereditary multiple exostoses gene products, in Golgi apparatus.
Kobayashi S; Morimoto K; Shimizu T; Takahashi M; Kurosawa H; Shirasawa T
Biochem Biophys Res Commun; 2000 Feb; 268(3):860-7. PubMed ID: 10679296
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]