BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

423 related articles for article (PubMed ID: 10866039)

  • 1. Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation.
    Bossenmaier B; Strack V; Stoyanov B; Krützfeldt J; Beck A; Lehmann R; Kellerer M; Klein H; Ullrich A; Lammers R; Häring HU
    Diabetes; 2000 Jun; 49(6):889-95. PubMed ID: 10866039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A 973 valine to methionine mutation of the human insulin receptor: interaction with insulin-receptor substrate-1 and Shc in HEK 293 cells.
    Strack V; Bossenmaier B; Stoyanov B; Mushack J; Häring HU
    Diabetologia; 1997 Oct; 40(10):1135-40. PubMed ID: 9349593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta.
    Strack V; Hennige AM; Krützfeldt J; Bossenmaier B; Klein HH; Kellerer M; Lammers R; Häring HU
    Diabetologia; 2000 Apr; 43(4):443-9. PubMed ID: 10819237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
    Cengel KA; Kason RE; Freund GG
    Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):397-404. PubMed ID: 9761740
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.
    Tobe K; Matuoka K; Tamemoto H; Ueki K; Kaburagi Y; Asai S; Noguchi T; Matsuda M; Tanaka S; Hattori S
    J Biol Chem; 1993 May; 268(15):11167-71. PubMed ID: 8388384
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteins.
    Solow BT; Harada S; Goldstein BJ; Smith JA; White MF; Jarett L
    Mol Endocrinol; 1999 Oct; 13(10):1784-98. PubMed ID: 10517679
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human insulin receptor juxtamembrane domain independent insulin signaling.
    Sattar AA; Berhanu C; Gebreselassie S; Berhanu P
    Cell Biol Int; 2007 Aug; 31(8):815-24. PubMed ID: 17344070
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

  • 9. IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85.
    Myers MG; Backer JM; Sun XJ; Shoelson S; Hu P; Schlessinger J; Yoakim M; Schaffhausen B; White MF
    Proc Natl Acad Sci U S A; 1992 Nov; 89(21):10350-4. PubMed ID: 1332046
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling.
    Goalstone ML; Leitner JW; Berhanu P; Sharma PM; Olefsky JM; Draznin B
    J Biol Chem; 2001 Apr; 276(16):12805-12. PubMed ID: 11278505
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of the NPXY motif in the insulin receptor in tyrosine phosphorylation of insulin receptor substrate-1 and Shc.
    Kaburagi Y; Yamamoto-Honda R; Tobe K; Ueki K; Yachi M; Akanuma Y; Stephens RM; Kaplan D; Yazaki Y; Kadowaki T
    Endocrinology; 1995 Aug; 136(8):3437-43. PubMed ID: 7543044
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin signal transduction by a mutant human insulin receptor lacking the NPEY sequence. Evidence for an alternate mitogenic signaling pathway that is independent of Shc phosphorylation.
    Berhanu P; Anderson C; Hickman M; Ciaraldi TP
    J Biol Chem; 1997 Sep; 272(36):22884-90. PubMed ID: 9278451
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Growth hormone stimulates the tyrosine kinase activity of JAK2 and induces tyrosine phosphorylation of insulin receptor substrates and Shc in rat tissues.
    Thirone AC; Carvalho CR; Saad MJ
    Endocrinology; 1999 Jan; 140(1):55-62. PubMed ID: 9886807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals.
    Esposito DL; Blakesley VA; Koval AP; Scrimgeour AG; LeRoith D
    Endocrinology; 1997 Jul; 138(7):2979-88. PubMed ID: 9202243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein kinase C isoforms alpha, delta and theta require insulin receptor substrate-1 to inhibit the tyrosine kinase activity of the insulin receptor in human kidney embryonic cells (HEK 293 cells).
    Kellerer M; Mushack J; Seffer E; Mischak H; Ullrich A; Häring HU
    Diabetologia; 1998 Jul; 41(7):833-8. PubMed ID: 9686926
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L; Zhou T; Jiang J; Pierce JH; Gustafson TA; Frank SJ
    Endocrinology; 1999 May; 140(5):1972-83. PubMed ID: 10218944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of insulin receptor substrate-1 (IRS-1) with phosphatidylinositol 3-kinase: effect of substitution of serine for alanine in potential IRS-1 serine phosphorylation sites.
    Delahaye L; Mothe-Satney I; Myers MG; White MF; Van Obberghen E
    Endocrinology; 1998 Dec; 139(12):4911-9. PubMed ID: 9832428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of insulin-stimulated glycogen synthesis by Src Homology Phosphatase 2.
    Ouwens DM; van der Zon GC; Maassen JA
    Mol Cell Endocrinol; 2001 Apr; 175(1-2):131-40. PubMed ID: 11325523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects.
    Krook A; Whitehead JP; Dobson SP; Griffiths MR; Ouwens M; Baker C; Hayward AC; Sen SK; Maassen JA; Siddle K; Tavaré JM; O'Rahilly S
    J Biol Chem; 1997 Nov; 272(48):30208-14. PubMed ID: 9374504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.
    Hers I; Bell CJ; Poole AW; Jiang D; Denton RM; Schaefer E; Tavaré JM
    Biochem J; 2002 Dec; 368(Pt 3):875-84. PubMed ID: 12220227
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.