These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 10866142)

  • 1. Bioavailable acyl-CoA: cholesterol acyltransferase inhibitor with anti-peroxidative activity: synthesis and biological activity of novel indolinyl amide and urea derivatives.
    Kamiya S; Shirahase H; Yoshimi A; Nakamura S; Kanda M; Matsui H; Kasai M; Takahashi K; Kurahashi K
    Chem Pharm Bull (Tokyo); 2000 Jun; 48(6):817-27. PubMed ID: 10866142
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel tetrahydroisoquinoline derivatives with inhibitory activities against acyl-CoA: cholesterol acyltransferase and lipid peroxidation.
    Ohta M; Takahashi K; Kasai M; Shoji Y; Kunishiro K; Miike T; Kanda M; Mukai C; Shirahase H
    Chem Pharm Bull (Tokyo); 2010 Aug; 58(8):1066-76. PubMed ID: 20686261
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
    Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
    Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypolipidemic and antioxidant activity of the novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor KY-455 in rabbits and hamsters.
    Nakamura S; Kamiya S; Shirahase H; Kanda M; Yoshimi A; Tarumi T; Kurahashi K
    Arzneimittelforschung; 2004; 54(2):102-8. PubMed ID: 15038459
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel indoline-based acyl-CoA:cholesterol acyltransferase inhibitor with antiperoxidative activity: improvement of physicochemical properties and biological activities by introduction of carboxylic acid.
    Takahashi K; Kasai M; Ohta M; Shoji Y; Kunishiro K; Kanda M; Kurahashi K; Shirahase H
    J Med Chem; 2008 Aug; 51(15):4823-33. PubMed ID: 18620381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activities.
    Shoji Y; Takahashi K; Ohta M; Kasai M; Kunishiro K; Kanda M; Yogai S; Takeuchi Y; Shirahase H
    Bioorg Med Chem; 2009 Aug; 17(16):6020-31. PubMed ID: 19608421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
    Kataoka K; Shiota T; Takeyasu T; Minoshima T; Watanabe K; Tanaka H; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
    J Med Chem; 1996 Mar; 39(6):1262-70. PubMed ID: 8632433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol.
    Riddell D; Bright CP; Burton BJ; Bush RC; Harris NV; Hele D; Moore UM; Naik K; Parrott DP; Smith C; Williams RJ
    Biochem Pharmacol; 1996 Oct; 52(8):1177-86. PubMed ID: 8937424
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acyl-CoA:Cholesterol O-acyltransferase (ACAT) inhibitors. 2. 2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT.
    Astles PC; Ashton MJ; Bridge AW; Harris NV; Hart TW; Parrott DP; Porter B; Riddell D; Smith C; Williams RJ
    J Med Chem; 1996 Mar; 39(7):1423-32. PubMed ID: 8691472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas.
    Tanaka A; Terasawa T; Hagihara H; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
    J Med Chem; 1998 Jun; 41(13):2390-410. PubMed ID: 9632372
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. synthesis and pharmacological activity of (+/-)-2-dodecyl-alpha-phenyl-N-(2,4,6-trimethoxyphenyl)-2H-tetrazole-5- acetamide and structurally related tetrazole amide derivatives.
    O'Brien PM; Sliskovic DR; Picard JA; Lee HT; Purchase CF; Roth BD; White AD; Anderson M; Mueller SB; Bocan T; Bousley R; Hamelehle KL; Homan R; Lee P; Krause BR; Reindel JF; Stanfield RL; Turluck D
    J Med Chem; 1996 Jun; 39(12):2354-66. PubMed ID: 8691430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides.
    Kataoka K; Shiota T; Takeyasu T; Mochizuki T; Taneda K; Ota M; Tanabe H; Yamaguchi H
    J Med Chem; 1995 Aug; 38(16):3174-86. PubMed ID: 7636880
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacological properties of R-755, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in cholesterol-fed rats, hamsters and rabbits.
    Matsui Y; Horiuchi K; Yamamoto K; Kanai K
    Jpn J Pharmacol; 2001 Apr; 85(4):423-33. PubMed ID: 11388647
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of SMP-500, a novel acyl-coA:cholesterol acyltransferase inhibitor, on the cholesterol esterification and its hypocholesterolemic properties.
    Ioriya K; Noguchi T; Muraoka M; Fujita K; Shimizu H; Ohashi N
    Pharmacology; 2002 May; 65(1):18-25. PubMed ID: 11901297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, X-ray crystal structure, and biological activity of FR186054, a novel, potent, orally active inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) bearing a pyrazole ring.
    Tanaka A; Terasawa T; Hagihara H; Kinoshita T; Sakuma Y; Ishibe N; Sawada M; Takasugi H; Tanaka H
    Bioorg Med Chem Lett; 1998 Jan; 8(1):81-6. PubMed ID: 9871633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RP 64477: a potent inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase with low systemic bioavailability.
    Bello AA; Bright C; Burton BJ; Bush RC; Casey JH; Dron DI; Facchini V; Joannou PP; Parrott DP; Riddell D; Roberts SA; Williams RJ
    Biochem Pharmacol; 1996 Feb; 51(4):413-21. PubMed ID: 8619885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Divergent pharmacologic activities of PD 132301-2 and CL 277,082, urea inhibitors of acyl-CoA:cholesterol acyltransferase.
    Krause BR; Black A; Bousley R; Essenburg A; Cornicelli J; Holmes A; Homan R; Kieft K; Sekerke C; Shaw-Hes MK
    J Pharmacol Exp Ther; 1993 Nov; 267(2):734-43. PubMed ID: 8246149
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of novel 4,5-diphenylthiazole derivatives as potential acyl-CoA:cholesterol O-acyltransferase inhibitors.
    Romeo G; Salerno L; Milla P; Siracusa M; Cattel L; Russo F
    Pharmazie; 1999 Jan; 54(1):19-23. PubMed ID: 9987793
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters.
    Sugiyama Y; Ishikawa E; Odaka H; Miki N; Tawada H; Ikeda H
    Atherosclerosis; 1995 Feb; 113(1):71-8. PubMed ID: 7755657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine and analogues as inhibitors of acyl-CoA: cholesterol O-acyltransferase.
    Ohishi K; Aiyama R; Hatano H; Yoshida Y; Wada Y; Yokoi W; Sawada H; Watanabe T; Yokokura T
    Chem Pharm Bull (Tokyo); 2001 Jul; 49(7):830-9. PubMed ID: 11456087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.