These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 10871858)

  • 1. Cdk inhibitors, roscovitine and olomoucine, synergize with farnesyltransferase inhibitor (FTI) to induce efficient apoptosis of human cancer cell lines.
    Edamatsu H; Gau CL; Nemoto T; Guo L; Tamanoi F
    Oncogene; 2000 Jun; 19(27):3059-68. PubMed ID: 10871858
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C; Rahmani M; Dai Y; Conrad D; Krystal G; Dent P; Grant S
    Cancer Res; 2003 Apr; 63(8):1822-33. PubMed ID: 12702569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity.
    Alessi F; Quarta S; Savio M; Riva F; Rossi L; Stivala LA; Scovassi AI; Meijer L; Prosperi E
    Exp Cell Res; 1998 Nov; 245(1):8-18. PubMed ID: 9828096
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells.
    Suzuki N; Urano J; Tamanoi F
    Proc Natl Acad Sci U S A; 1998 Dec; 95(26):15356-61. PubMed ID: 9860973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Apoptosis of metastatic prostate cancer cells by a combination of cyclin-dependent kinase and AKT inhibitors.
    Mohapatra S; Chu B; Zhao X; Djeu J; Cheng JQ; Pledger WJ
    Int J Biochem Cell Biol; 2009 Mar; 41(3):595-602. PubMed ID: 18708158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK inhibitors induce mitochondria-mediated apoptosis through the activation of polyamine catabolic pathway in LNCaP, DU145 and PC3 prostate cancer cells.
    Arisan ED; Obakan P; Coker-Gurkan A; Calcabrini A; Agostinelli E; Unsal NP
    Curr Pharm Des; 2014; 20(2):180-8. PubMed ID: 23701543
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roscovitine, olomoucine, purvalanol: inducers of apoptosis in maturing cerebellar granule neurons.
    Monaco EA; Beaman-Hall CM; Mathur A; Vallano ML
    Biochem Pharmacol; 2004 May; 67(10):1947-64. PubMed ID: 15130771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effect of the cyclin-dependent kinase inhibitor olomoucine on cell cycle kinetics.
    Schutte B; Nieland L; van Engeland M; Henfling ME; Meijer L; Ramaekers FC
    Exp Cell Res; 1997 Oct; 236(1):4-15. PubMed ID: 9344580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclin-dependent kinase inhibitors block proliferation of human gastric cancer cells.
    Iseki H; Ko TC; Xue XY; Seapan A; Hellmich MR; Townsend CM
    Surgery; 1997 Aug; 122(2):187-94; discussion 194-5. PubMed ID: 9288122
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell differentiation, caspase inhibition, and macromolecular synthesis blockage, but not BCL-2 or BCL-XL proteins, protect SH-SY5Y cells from apoptosis triggered by two CDK inhibitory drugs.
    Ribas J; Boix J
    Exp Cell Res; 2004 Apr; 295(1):9-24. PubMed ID: 15051486
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of human immunodeficiency virus type 1 transcription by chemical cyclin-dependent kinase inhibitors.
    Wang D; de la Fuente C; Deng L; Wang L; Zilberman I; Eadie C; Healey M; Stein D; Denny T; Harrison LE; Meijer L; Kashanchi F
    J Virol; 2001 Aug; 75(16):7266-79. PubMed ID: 11461999
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of polyamine oxidase prevented cyclin-dependent kinase inhibitor-induced apoptosis in HCT 116 colon carcinoma cells.
    Gürkan AC; Arisan ED; Obakan P; Palavan-Ünsal N
    Apoptosis; 2013 Dec; 18(12):1536-47. PubMed ID: 23892915
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caspase 8/10 are not mediating apoptosis in neuroblastoma cells treated with CDK inhibitory drugs.
    Ribas J; Gomez-Arbones X; Boix J
    Eur J Pharmacol; 2005 Nov; 524(1-3):49-52. PubMed ID: 16243312
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cell cycle arrest induced in human breast cancer cells by cyclin-dependent kinase inhibitors: a comparison of the effects exerted by roscovitine and olomoucine.
    Wesierska-Gadek J; Gueorguieva M; Wojciechowski J; Horky M
    Pol J Pharmacol; 2004; 56(5):635-41. PubMed ID: 15591654
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel strategy for inhibiting growth of human pancreatic cancer cells by blocking cyclin-dependent kinase activity.
    Iseki H; Ko TC; Xue XY; Seapan A; Townsend CM
    J Gastrointest Surg; 1998; 2(1):36-43. PubMed ID: 9841966
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced roscovitine-induced apoptosis is mediated by a caspase-3-like activity in deoxyadenosine-resistant mouse leukemia L1210 cells.
    Somerville L; Cory JG
    Anticancer Res; 2000; 20(5B):3347-55. PubMed ID: 11131634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors.
    Maas JW; Horstmann S; Borasio GD; Anneser JM; Shooter EM; Kahle PJ
    J Neurochem; 1998 Apr; 70(4):1401-10. PubMed ID: 9523556
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of autophagy by 3-MA potentiates purvalanol-induced apoptosis in Bax deficient HCT 116 colon cancer cells.
    Coker-Gurkan A; Arisan ED; Obakan P; Guvenir E; Unsal NP
    Exp Cell Res; 2014 Oct; 328(1):87-98. PubMed ID: 25088259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential.
    Lahusen T; De Siervi A; Kunick C; Senderowicz AM
    Mol Carcinog; 2003 Apr; 36(4):183-94. PubMed ID: 12669310
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Early inhibition of DNA synthesis in the developing rat cerebral cortex by the purine analogues olomoucine and roscovitine.
    Yakisich JS; Sidén A; Idoyaga Vargas V; Eneroth P; Cruz M
    Biochem Biophys Res Commun; 1998 Feb; 243(3):674-7. PubMed ID: 9500988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.