BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

322 related articles for article (PubMed ID: 10874126)

  • 1. Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation.
    McSorley LC; Daly AK
    Biochem Pharmacol; 2000 Aug; 60(4):517-26. PubMed ID: 10874126
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H; Shimada T
    Xenobiotica; 1999 Mar; 29(3):231-41. PubMed ID: 10219964
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone.
    Baldwin SJ; Clarke SE; Chenery RJ
    Br J Clin Pharmacol; 1999 Sep; 48(3):424-32. PubMed ID: 10510156
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro.
    Chang SY; Li W; Traeger SC; Wang B; Cui D; Zhang H; Wen B; Rodrigues AD
    Drug Metab Dispos; 2008 Dec; 36(12):2513-22. PubMed ID: 18787056
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor.
    Tang C; Shou M; Mei Q; Rushmore TH; Rodrigues AD
    J Pharmacol Exp Ther; 2000 May; 293(2):453-9. PubMed ID: 10773015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of CYP2C in the in vitro bioactivation of the contraceptive steroid desogestrel.
    Gentile DM; Verhoeven CH; Shimada T; Back DJ
    J Pharmacol Exp Ther; 1998 Dec; 287(3):975-82. PubMed ID: 9864282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively.
    Wen X; Wang JS; Backman JT; Laitila J; Neuvonen PJ
    Drug Metab Dispos; 2002 Jun; 30(6):631-5. PubMed ID: 12019187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X; Wang JS; Kivistö KT; Neuvonen PJ; Backman JT
    Br J Clin Pharmacol; 2001 Nov; 52(5):547-53. PubMed ID: 11736863
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5.
    Huang Z; Guengerich FP; Kaminsky LS
    Carcinogenesis; 1998 May; 19(5):867-72. PubMed ID: 9635876
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of human cytochrome P450 1A1, 1A2, 1B1, and 3A4 in the 2-, 4-, and 16alpha-hydroxylation of 17beta-estradiol.
    Badawi AF; Cavalieri EL; Rogan EG
    Metabolism; 2001 Sep; 50(9):1001-3. PubMed ID: 11555828
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Drug Metab Dispos; 2002 May; 30(5):602-7. PubMed ID: 11950794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4.
    Feierman DE; Lasker JM
    Drug Metab Dispos; 1996 Sep; 24(9):932-9. PubMed ID: 8886601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R; Roe EG; Jones BC; Smith DA
    Br J Clin Pharmacol; 2001 Mar; 51(3):239-48. PubMed ID: 11298070
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of CYP2C19 and CYP2C9 from human liver: respective roles in microsomal tolbutamide, S-mephenytoin, and omeprazole hydroxylations.
    Lasker JM; Wester MR; Aramsombatdee E; Raucy JL
    Arch Biochem Biophys; 1998 May; 353(1):16-28. PubMed ID: 9578596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.
    Transon C; Lecoeur S; Leemann T; Beaune P; Dayer P
    Eur J Clin Pharmacol; 1996; 51(1):79-85. PubMed ID: 8880056
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms.
    Stresser DM; Kupfer D
    Biochem Pharmacol; 1998 Jun; 55(11):1861-71. PubMed ID: 9714305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR; Lasker JM; Johnson EF; Raucy JL
    Drug Metab Dispos; 2000 Mar; 28(3):354-9. PubMed ID: 10681382
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Progesterone and testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes.
    Yamazaki H; Shimada T
    Arch Biochem Biophys; 1997 Oct; 346(1):161-9. PubMed ID: 9328296
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro.
    Ufer M; Svensson JO; Krausz KW; Gelboin HV; Rane A; Tybring G
    Eur J Clin Pharmacol; 2004 May; 60(3):173-82. PubMed ID: 15054565
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.