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3. A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. De Strooper B; Annaert W; Cupers P; Saftig P; Craessaerts K; Mumm JS; Schroeter EH; Schrijvers V; Wolfe MS; Ray WJ; Goate A; Kopan R Nature; 1999 Apr; 398(6727):518-22. PubMed ID: 10206645 [TBL] [Abstract][Full Text] [Related]
4. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens. Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567 [TBL] [Abstract][Full Text] [Related]
5. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Wolfe MS; Xia W; Ostaszewski BL; Diehl TS; Kimberly WT; Selkoe DJ Nature; 1999 Apr; 398(6727):513-7. PubMed ID: 10206644 [TBL] [Abstract][Full Text] [Related]
6. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism. Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948 [TBL] [Abstract][Full Text] [Related]
7. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms. Bentahir M; Nyabi O; Verhamme J; Tolia A; Horré K; Wiltfang J; Esselmann H; De Strooper B J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513 [TBL] [Abstract][Full Text] [Related]
8. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein. De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F Nature; 1998 Jan; 391(6665):387-90. PubMed ID: 9450754 [TBL] [Abstract][Full Text] [Related]
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13. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation. Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; Nishimura M; Yanagisawa K; Komano H J Neurochem; 2004 Sep; 90(6):1402-13. PubMed ID: 15341524 [TBL] [Abstract][Full Text] [Related]
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18. Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane. Kaether C; Lammich S; Edbauer D; Ertl M; Rietdorf J; Capell A; Steiner H; Haass C J Cell Biol; 2002 Aug; 158(3):551-61. PubMed ID: 12147673 [TBL] [Abstract][Full Text] [Related]
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