207 related articles for article (PubMed ID: 10887202)
1. Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.
Haniu M; Denis P; Young Y; Mendiaz EA; Fuller J; Hui JO; Bennett BD; Kahn S; Ross S; Burgess T; Katta V; Rogers G; Vassar R; Citron M
J Biol Chem; 2000 Jul; 275(28):21099-106. PubMed ID: 10887202
[TBL] [Abstract][Full Text] [Related]
2. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
3. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
[TBL] [Abstract][Full Text] [Related]
4. Maturation and endosomal targeting of beta-site amyloid precursor protein-cleaving enzyme. The Alzheimer's disease beta-secretase.
Huse JT; Pijak DS; Leslie GJ; Lee VM; Doms RW
J Biol Chem; 2000 Oct; 275(43):33729-37. PubMed ID: 10924510
[TBL] [Abstract][Full Text] [Related]
5. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
Sauder JM; Arthur JW; Dunbrack RL
J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
[TBL] [Abstract][Full Text] [Related]
6. Substrate and inhibitor profile of BACE (beta-secretase) and comparison with other mammalian aspartic proteases.
Grüninger-Leitch F; Schlatter D; Küng E; Nelböck P; Döbeli H
J Biol Chem; 2002 Feb; 277(7):4687-93. PubMed ID: 11741910
[TBL] [Abstract][Full Text] [Related]
7. Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production.
Benjannet S; Elagoz A; Wickham L; Mamarbachi M; Munzer JS; Basak A; Lazure C; Cromlish JA; Sisodia S; Checler F; Chrétien M; Seidah NG
J Biol Chem; 2001 Apr; 276(14):10879-87. PubMed ID: 11152688
[TBL] [Abstract][Full Text] [Related]
8. A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
Bennett BD; Denis P; Haniu M; Teplow DB; Kahn S; Louis JC; Citron M; Vassar R
J Biol Chem; 2000 Dec; 275(48):37712-7. PubMed ID: 10956649
[TBL] [Abstract][Full Text] [Related]
9. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
10. Characterization of recombinant, soluble beta-secretase from an insect cell expression system.
Mallender WD; Yager D; Onstead L; Nichols MR; Eckman C; Sambamurti K; Kopcho LM; Marcinkeviciene J; Copeland RA; Rosenberry TL
Mol Pharmacol; 2001 Mar; 59(3):619-26. PubMed ID: 11179458
[TBL] [Abstract][Full Text] [Related]
11. Maturation and pro-peptide cleavage of beta-secretase.
Capell A; Steiner H; Willem M; Kaiser H; Meyer C; Walter J; Lammich S; Multhaup G; Haass C
J Biol Chem; 2000 Oct; 275(40):30849-54. PubMed ID: 10801872
[TBL] [Abstract][Full Text] [Related]
12. The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity.
Fischer F; Molinari M; Bodendorf U; Paganetti P
J Neurochem; 2002 Mar; 80(6):1079-88. PubMed ID: 11953458
[TBL] [Abstract][Full Text] [Related]
13. Recombinant insect cell expression and purification of human beta-secretase (BACE-1) for X-ray crystallography.
Bruinzeel W; Yon J; Giovannelli S; Masure S
Protein Expr Purif; 2002 Oct; 26(1):139-48. PubMed ID: 12356481
[TBL] [Abstract][Full Text] [Related]
14. Beta-amyloid peptide in regulated secretory vesicles of chromaffin cells: evidence for multiple cysteine proteolytic activities in distinct pathways for beta-secretase activity in chromaffin vesicles.
Hook VY; Toneff T; Aaron W; Yasothornsrikul S; Bundey R; Reisine T
J Neurochem; 2002 Apr; 81(2):237-56. PubMed ID: 12064471
[TBL] [Abstract][Full Text] [Related]
15. A non-amyloidogenic function of BACE-2 in the secretory pathway.
Fluhrer R; Capell A; Westmeyer G; Willem M; Hartung B; Condron MM; Teplow DB; Haass C; Walter J
J Neurochem; 2002 Jun; 81(5):1011-20. PubMed ID: 12065613
[TBL] [Abstract][Full Text] [Related]
16. Amyloid precursor protein compartmentalization restricts beta-amyloid production: therapeutic targets based on BACE compartmentalization.
Gandhi S; Refolo LM; Sambamurti K
J Mol Neurosci; 2004; 24(1):137-43. PubMed ID: 15314262
[TBL] [Abstract][Full Text] [Related]
17. Cysteine proteases are the major beta-secretase in the regulated secretory pathway that provides most of the beta-amyloid in Alzheimer's disease: role of BACE 1 in the constitutive secretory pathway.
Hook VY; Reisine TD
J Neurosci Res; 2003 Nov; 74(3):393-405. PubMed ID: 14598316
[TBL] [Abstract][Full Text] [Related]
18. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
Vassar R
J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
[TBL] [Abstract][Full Text] [Related]
19. Characterization of the glycosylation profiles of Alzheimer's beta -secretase protein Asp-2 expressed in a variety of cell lines.
Charlwood J; Dingwall C; Matico R; Hussain I; Johanson K; Moore S; Powell DJ; Skehel JM; Ratcliffe S; Clarke B; Trill J; Sweitzer S; Camilleri P
J Biol Chem; 2001 May; 276(20):16739-48. PubMed ID: 11278492
[TBL] [Abstract][Full Text] [Related]
20. Endoproteolysis of beta-secretase (beta-site amyloid precursor protein-cleaving enzyme) within its catalytic domain. A potential mechanism for regulation.
Huse JT; Byant D; Yang Y; Pijak DS; D'Souza I; Lah JJ; Lee VM; Doms RW; Cook DG
J Biol Chem; 2003 May; 278(19):17141-9. PubMed ID: 12551920
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
