BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 10890168)

  • 1. Synthesis and resolution of racemic eliprodil and evaluation of the enantiomers of eliprodil as NMDA receptor antagonists.
    Pabel J; Höfner G; Wanner KT
    Bioorg Med Chem Lett; 2000 Jun; 10(12):1377-80. PubMed ID: 10890168
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of (R)-1-[2-hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: a novel NR1/2B subtype selective NMDA receptor antagonist.
    Pinard E; Alanine A; Bourson A; Büttelmann B; Gill R; Heitz M; Jaeschke G; Mutel V; Trube G; Wyler R
    Bioorg Med Chem Lett; 2001 Aug; 11(16):2173-6. PubMed ID: 11514163
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Anticonvulsant effects of eliprodil alone or combined with the glycineB receptor antagonist L-701,324 or the competitive NMDA antagonist CGP 40116 in the amygdala kindling model in rats.
    Wlaź P; Ebert U; Löscher W
    Neuropharmacology; 1999 Feb; 38(2):243-51. PubMed ID: 10218865
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antagonist properties of eliprodil and other NMDA receptor antagonists at rat NR1A/NR2A and NR1A/NR2B receptors expressed in Xenopus oocytes.
    Avenet P; Léonardon J; Besnard F; Graham D; Depoortere H; Scatton B
    Neurosci Lett; 1997 Feb; 223(2):133-6. PubMed ID: 9089691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.
    Guzikowski AP; Tamiz AP; Acosta-Burruel M; Hong-Bae S; Cai SX; Hawkinson JE; Keana JF; Kesten SR; Shipp CT; Tran M; Whittemore ER; Woodward RM; Wright JL; Zhou ZL
    J Med Chem; 2000 Mar; 43(5):984-94. PubMed ID: 10715162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.
    Gregory TF; Wright JL; Wise LD; Meltzer LT; Serpa KA; Konkoy CS; Whittemore ER; Woodward RM
    Bioorg Med Chem Lett; 2000 Mar; 10(6):527-9. PubMed ID: 10741546
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chiral synthesis and pharmacological evaluation of NPS 1407: a potent, stereoselective NMDA receptor antagonist.
    Moe ST; Smith DL; DelMar EG; Shimizu SM; Van Wagenen BC; Balandrin MF; Chien YE; Raszkiewicz JL; Artman LD; White HS; Mueller AL
    Bioorg Med Chem Lett; 2000 Nov; 10(21):2411-5. PubMed ID: 11078190
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Place conditioning of mice with the NMDA receptor antagonists, eliprodil and dizocilpine.
    Sukhotina I; Dravolina O; Bespalov A
    Eur J Pharmacol; 1998 Dec; 362(2-3):103-10. PubMed ID: 9874159
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Eliprodil, a non-competitive, NR2B-selective NMDA antagonist, protects pyramidal neurons in hippocampal slices from hypoxic/ischemic damage.
    Reyes M; Reyes A; Opitz T; Kapin MA; Stanton PK
    Brain Res; 1998 Jan; 782(1-2):212-8. PubMed ID: 9519265
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of a series of γ-amino alcohols comprising an N-methyl isoindoline moiety and their evaluation as NMDA receptor antagonists.
    Müller A; Höfner G; Renukappa-Gutke T; Parsons CG; Wanner KT
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5795-9. PubMed ID: 21875803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subtype-selective N-methyl-D-aspartate receptor antagonists: synthesis and biological evaluation of 1-(arylalkynyl)-4-benzylpiperidines.
    Wright JL; Gregory TF; Bigge CF; Boxer PA; Serpa K; Meltzer LT; Wise LD; Cai SX; Hawkinson JE; Konkoy CS; Whittemore ER; Woodward RM; Zhou ZL
    J Med Chem; 1999 Jul; 42(13):2469-77. PubMed ID: 10395488
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.
    Zhou ZL; Cai SX; Whittemore ER; Konkoy CS; Espitia SA; Tran M; Rock DM; Coughenour LL; Hawkinson JE; Boxer PA; Bigge CF; Wise LD; Weber E; Woodward RM; Keana JF
    J Med Chem; 1999 Jul; 42(15):2993-3000. PubMed ID: 10425109
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.
    Wang CX; Shuaib A
    Curr Drug Targets CNS Neurol Disord; 2005 Apr; 4(2):143-51. PubMed ID: 15857299
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists.
    Banerjee A; Schepmann D; Köhler J; Würthwein EU; Wünsch B
    Bioorg Med Chem; 2010 Nov; 18(22):7855-67. PubMed ID: 20965735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes.
    Pahk AJ; Williams K
    Neurosci Lett; 1997 Mar; 225(1):29-32. PubMed ID: 9143010
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Syntheses, activity and modeling studies of 3- and 4-(sulfo- and sulfonamidoalkyl)pyridine and piperidine-2-carboxylic acid derivatives as analogs of NMDA receptor antagonists.
    el Hadri A; Maldivi P; Leclerc G; Rocher JP
    Bioorg Med Chem; 1995 Sep; 3(9):1183-201. PubMed ID: 8564410
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Block of P-type Ca2+ channels by the NMDA receptor antagonist eliprodil in acutely dissociated rat Purkinje cells.
    Biton B; Granger P; Depoortere H; Scatton B; Avenet P
    Eur J Pharmacol; 1995 Dec; 294(1):91-100. PubMed ID: 8788420
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Pharmacological Evaluation of Enantiomerically Pure GluN2B Selective NMDA Receptor Antagonists.
    Börgel F; Szermerski M; Schreiber JA; Temme L; Strutz-Seebohm N; Lehmkuhl K; Schepmann D; Ametamey SM; Seebohm G; Schmidt TJ; Wünsch B
    ChemMedChem; 2018 Aug; 13(15):1580-1587. PubMed ID: 29806151
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antagonists selective for NMDA receptors containing the NR2B subunit.
    Chenard BL; Menniti FS
    Curr Pharm Des; 1999 May; 5(5):381-404. PubMed ID: 10213801
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia.
    Bath CP; Farrell LN; Gilmore J; Ward MA; Hicks CA; O'Neill MJ; Bleakman D
    Eur J Pharmacol; 1996 Mar; 299(1-3):103-12. PubMed ID: 8901012
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.