BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 10894884)

  • 21. In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice.
    Cho SH; Guengerich FP
    Chem Res Toxicol; 2013 Nov; 26(11):1765-74. PubMed ID: 24191644
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Human O(6)-alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes.
    Abril N; Luque-Romero FL; Christians FC; Encell LP; Loeb LA; Pueyo C
    Carcinogenesis; 1999 Nov; 20(11):2089-94. PubMed ID: 10545410
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.
    Crone TM; Pegg AE
    Cancer Res; 1993 Oct; 53(20):4750-3. PubMed ID: 8402653
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Repair of oligodeoxyribonucleotides by O(6)-alkylguanine-DNA alkyltransferase.
    Luu KX; Kanugula S; Pegg AE; Pauly GT; Moschel RC
    Biochemistry; 2002 Jul; 41(27):8689-97. PubMed ID: 12093287
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy.
    Davis BM; Roth JC; Liu L; Xu-Welliver M; Pegg AE; Gerson SL
    Hum Gene Ther; 1999 Nov; 10(17):2769-78. PubMed ID: 10584923
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Characterization of a mutagenic DNA adduct formed from 1,2-dibromoethane by O6-alkylguanine-DNA alkyltransferase.
    Liu L; Hachey DL; Valadez G; Williams KM; Guengerich FP; Loktionova NA; Kanugula S; Pegg AE
    J Biol Chem; 2004 Feb; 279(6):4250-9. PubMed ID: 14645247
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Activation of bis-electrophiles to mutagenic conjugates by human O6-alkylguanine-DNA alkyltransferase.
    Valadez JG; Liu L; Loktionova NA; Pegg AE; Guengerich FP
    Chem Res Toxicol; 2004 Jul; 17(7):972-82. PubMed ID: 15257623
    [TBL] [Abstract][Full Text] [Related]  

  • 28. ogt alkyltransferase enhances dibromoalkane mutagenicity in excision repair-deficient Escherichia coli K-12.
    Abril N; Luque-Romero FL; Prieto-Alamo MJ; Margison GP; Pueyo C
    Mol Carcinog; 1995 Feb; 12(2):110-7. PubMed ID: 7662116
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine.
    Crone TM; Goodtzova K; Edara S; Pegg AE
    Cancer Res; 1994 Dec; 54(23):6221-7. PubMed ID: 7954470
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Degradation of the alkylated form of the DNA repair protein, O(6)-alkylguanine-DNA alkyltransferase.
    Xu-Welliver M; Pegg AE
    Carcinogenesis; 2002 May; 23(5):823-30. PubMed ID: 12016156
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The repair of the tobacco specific nitrosamine derived adduct O6-[4-Oxo-4-(3-pyridyl)butyl]guanine by O6-alkylguanine-DNA alkyltransferase variants.
    Mijal RS; Thomson NM; Fleischer NL; Pauly GT; Moschel RC; Kanugula S; Fang Q; Pegg AE; Peterson LA
    Chem Res Toxicol; 2004 Mar; 17(3):424-34. PubMed ID: 15025514
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Lack of evidence for a polymorphism at codon 160 of human O6-alkylguanine-DNA alkyltransferase gene in normal tissue and cancer.
    Wu MH; Lohrbach KE; Olopade OI; Kokkinakis DM; Friedman HS; Dolan ME
    Clin Cancer Res; 1999 Jan; 5(1):209-13. PubMed ID: 9918221
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
    Liu L; Schwartz S; Davis BM; Gerson SL
    Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Genetic polymorphism of human O6-alkylguanine-DNA alkyltransferase: identification of a missense variation in the active site region.
    Deng C; Xie D; Capasso H; Zhao Y; Wang LD; Hong JY
    Pharmacogenetics; 1999 Feb; 9(1):81-7. PubMed ID: 10208646
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mutations in the Ada O6-alkylguanine-DNA alkyltransferase conferring sensitivity to inactivation by O6-benzylguanine and 2,4-diamino-6-benzyloxy-5-nitrosopyrimidine.
    Crone TM; Kanugula S; Pegg AE
    Carcinogenesis; 1995 Aug; 16(8):1687-92. PubMed ID: 7634390
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Distinct pathways for repairing mutagenic lesions induced by methylating and ethylating agents.
    Taira K; Kaneto S; Nakano K; Watanabe S; Takahashi E; Arimoto S; Okamoto K; Schaaper RM; Negishi K; Negishi T
    Mutagenesis; 2013 May; 28(3):341-50. PubMed ID: 23446177
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Point mutations in human O6-alkylguanine-DNA alkyltransferase prevent the sensitization by O6-benzylguanine to killing by N,N'-bis (2-chloroethyl)-N-nitrosourea.
    Loktionova NA; Pegg AE
    Cancer Res; 1996 Apr; 56(7):1578-83. PubMed ID: 8603405
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Function of domains of human O6-alkylguanine-DNA alkyltransferase.
    Fang Q; Kanugula S; Pegg AE
    Biochemistry; 2005 Nov; 44(46):15396-405. PubMed ID: 16285744
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    Maze R; Kurpad C; Pegg AE; Erickson LC; Williams DA
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1467-74. PubMed ID: 10454526
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine].
    Wan Y; Wu D; Gao H
    Zhonghua Zhong Liu Za Zhi; 2000 Jul; 22(4):290-3. PubMed ID: 11778552
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.