BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 10901290)

  • 1. Synthesis and enantioselectivity of the antiviral effects of (R,Z)-,(S,Z)-methylenecyclopropane analogues of purine nucleosides and phosphoralaninate prodrugs: influence of heterocyclic base, type of virus and host cells.
    Qiu YL; Geiser F; Kira T; Gullen E; Cheng YC; Ptak RG; Breitenbach JM; Drach JC; Hartline CB; Kern ER; Zemlicka J
    Antivir Chem Chemother; 2000 May; 11(3):191-202. PubMed ID: 10901290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides.
    Zhou S; Breitenbach JM; Borysko KZ; Drach JC; Kern ER; Gullen E; Cheng YC; Zemlicka J
    J Med Chem; 2004 Jan; 47(3):566-75. PubMed ID: 14736238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antiviral activity of phosphoralaninate derivatives of methylenecyclopropane analogues of nucleosides.
    Qiu YL; Ptak RG; Breitenbach JM; Lin JS; Cheng YC; Drach JC; Kern ER; Zemlicka J
    Antiviral Res; 1999 Aug; 43(1):37-53. PubMed ID: 10480262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. (R)-(-)- and (S)-(+)-Synadenol: synthesis, absolute configuration, and enantioselectivity of antiviral effect.
    Qiu YL; Hempel A; Camerman N; Camerman A; Geiser F; Ptak RG; Breitenbach JM; Kira T; Li L; Gullen E; Cheng YC; Drach JC; Zemlicka J
    J Med Chem; 1998 Dec; 41(26):5257-64. PubMed ID: 9857093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. (Z)- and (E)-2-(hydroxymethylcyclopropylidene)-methylpurines and pyrimidines as antiviral agents.
    Qiu YL; Ptak RG; Breitenbach JM; Lin JS; Cheng YC; Kern ER; Drach JC; Zemlicka J
    Antivir Chem Chemother; 1998 Jul; 9(4):341-52. PubMed ID: 9875413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. (Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
    Qiu YL; Ksebati MB; Ptak RG; Fan BY; Breitenbach JM; Lin JS; Cheng YC; Kern ER; Drach JC; Zemlicka J
    J Med Chem; 1998 Jan; 41(1):10-23. PubMed ID: 9438017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of (Z)- and (E)-9-[(2-hydroxyethylidene)cyclopropyl]adenine--new methylenecyclopropane analogues of adenosine and their substrate activity for adenosine deaminase.
    Qui YL; Ksebati MB; Zemlicka J
    Nucleosides Nucleotides Nucleic Acids; 2000; 19(1-2):31-7. PubMed ID: 10772701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
    Ambrose A; Zemlicka J; Kern ER; Drach JC; Gullen E; Cheng YC
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(10-12):1763-74. PubMed ID: 16438046
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
    Zhou S; Kern ER; Gullen E; Cheng YC; Drach JC; Tamiya S; Mitsuya H; Zemlicka J
    J Med Chem; 2006 Oct; 49(20):6120-8. PubMed ID: 17004726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. (Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
    Zhou S; Kern ER; Gullen E; Cheng YC; Drach JC; Matsumi S; Mitsuya H; Zemlicka J
    J Med Chem; 2004 Dec; 47(27):6964-72. PubMed ID: 15615545
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro.
    Kushner NL; Williams SL; Hartline CB; Harden EA; Bidanset DJ; Chen X; Zemlicka J; Kern ER
    Nucleosides Nucleotides Nucleic Acids; 2003 Dec; 22(12):2105-19. PubMed ID: 14714760
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro activities of methylenecyclopropane analogues of nucleosides and their phosphoralaninate prodrugs against cytomegalovirus and other herpesvirus infections.
    Rybak RJ; Hartline CB; Qiu YL; Zemlicka J; Harden E; Marshall G; Sommadossi JP; Kern ER
    Antimicrob Agents Chemother; 2000 Jun; 44(6):1506-11. PubMed ID: 10817700
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylenecyclopropane analogues of nucleosides: synthesis, absolute configuration, and enantioselectivity of antiviral effect of (R)-(-)- and (S)-(+)-synadenol.
    Qiu YL; Hempel A; Camerman N; Camerman A; Geiser F; Ptak RG; Breitenbach JM; Kira T; Li L; Gullen E; Cheng YC; Drach JC; Zemlicka J
    Nucleosides Nucleotides; 1999; 18(4-5):597-8. PubMed ID: 10432651
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus.
    Chen X; Kern ER; Drach JC; Gullen E; Cheng YC; Zemlicka J
    J Med Chem; 2003 Apr; 46(8):1531-7. PubMed ID: 12672254
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of methylenecyclobutane analogues of nucleosides with axial chirality and their phosphoralaninates: a new pronucleotide effective against Epstein-Barr virus.
    Wang R; Kern ER; Zemlicka J
    Antivir Chem Chemother; 2002 Jul; 13(4):251-62. PubMed ID: 12495213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir.
    Li C; Quenelle DC; Prichard MN; Drach JC; Zemlicka J
    Bioorg Med Chem; 2012 Apr; 20(8):2669-74. PubMed ID: 22417649
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antiviral activities of methylenecyclopropane analogs with 6-alkoxy and 6-alkylthio substitutions that exhibit broad-spectrum antiviral activity against human herpesviruses.
    Prichard MN; Williams JD; Komazin-Meredith G; Khan AR; Price NB; Jefferson GM; Harden EA; Hartline CB; Peet NP; Bowlin TL
    Antimicrob Agents Chemother; 2013 Aug; 57(8):3518-27. PubMed ID: 23669381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antiviral activity of 2'-deoxy-4'-thio purine nucleosides.
    Van Draanen NA; Freeman GA; Short SA; Harvey R; Jansen R; Szczech G; Koszalka GW
    J Med Chem; 1996 Jan; 39(2):538-42. PubMed ID: 8558524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The enantiomers of carbocyclic 5'-norguanosine: activity towards Epstein-Barr virus.
    Rajappan V; Schneller SW; Williams SL; Kern ER
    Bioorg Med Chem; 2002 Apr; 10(4):883-6. PubMed ID: 11836094
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Spiropentane mimics of nucleosides: analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, isomeric assignment, and biological activity.
    Guan HP; Ksebati MB; Cheng YC; Drach JC; Kern ER; Zemlicka J
    J Org Chem; 2000 Mar; 65(5):1280-90. PubMed ID: 10814087
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.