BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 10903801)

  • 1. Lck is involved in interleukin-2 induced proliferation but not cell survival in human T cells through a MAP kinase-independent pathway.
    Brockdorff J; Nielsen M; Kaltoft K; Mustelin T; Röpke C; Svejaard A; Geisler C; Odum N
    Eur Cytokine Netw; 2000 Jun; 11(2):225-31. PubMed ID: 10903801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lck associates with and is activated by Kit in a small cell lung cancer cell line: inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1.
    Krystal GW; DeBerry CS; Linnekin D; Litz J
    Cancer Res; 1998 Oct; 58(20):4660-6. PubMed ID: 9788619
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lactoferrin upregulates the expression of CD4 antigen through the stimulation of the mitogen-activated protein kinase in the human lymphoblastic T Jurkat cell line.
    Dhennin-Duthille I; Masson M; Damiens E; Fillebeen C; Spik G; Mazurier J
    J Cell Biochem; 2000 Sep; 79(4):583-93. PubMed ID: 10996849
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vivo association between p56lck and MAP kinase during IL-2-mediated lymphocyte proliferation.
    Taieb J; Blanchard DA; Auffredou MT; Chaouchi N; Vazquez A
    J Immunol; 1995 Dec; 155(12):5623-30. PubMed ID: 7499846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of caspase or FADD function blocks proliferation but not MAP kinase-activation and interleukin-2-production during primary stimulation of T cells.
    Mack A; Häcker G
    Eur J Immunol; 2002 Jul; 32(7):1986-92. PubMed ID: 12115619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for the involvement of LCK and MAP kinase (ERK-1) in the signal transduction mechanism of interleukin-15.
    Adunyah SE; Wheeler BJ; Cooper RS
    Biochem Biophys Res Commun; 1997 Mar; 232(3):754-8. PubMed ID: 9126349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of src family lck tyrosine kinase following interleukin-12 activation of human natural killer cells.
    Pignata C; Prasad KV; Hallek M; Druker B; Rudd CE; Robertson MJ; Ritz J
    Cell Immunol; 1995 Oct; 165(2):211-6. PubMed ID: 7553885
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-18 induces activation and association of p56(lck) and MAPK in a murine TH1 clone.
    Tsuji-Takayama K; Matsumoto S; Koide K; Takeuchi M; Ikeda M; Ohta T; Kurimoto M
    Biochem Biophys Res Commun; 1997 Aug; 237(1):126-30. PubMed ID: 9266843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
    DiMauro EF; Newcomb J; Nunes JJ; Bemis JE; Boucher C; Chai L; Chaffee SC; Deak HL; Epstein LF; Faust T; Gallant P; Gore A; Gu Y; Henkle B; Hsieh F; Huang X; Kim JL; Lee JH; Martin MW; McGowan DC; Metz D; Mohn D; Morgenstern KA; Oliveira-dos-Santos A; Patel VF; Powers D; Rose PE; Schneider S; Tomlinson SA; Tudor YY; Turci SM; Welcher AA; Zhao H; Zhu L; Zhu X
    J Med Chem; 2008 Mar; 51(6):1681-94. PubMed ID: 18321037
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IL-2 stimulation of T lymphocytes induces sequential activation of mitogen-activated protein kinases and phosphorylation of p56lck at serine-59.
    Watts JD; Welham MJ; Kalt L; Schrader JW; Aebersold R
    J Immunol; 1993 Dec; 151(12):6862-71. PubMed ID: 8258696
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of human T cell activation by novel Src kinase inhibitors is dependent upon the complexity of the signal delivered to the cell.
    Rapecki S; Allen R
    J Pharmacol Exp Ther; 2002 Dec; 303(3):1325-33. PubMed ID: 12438558
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection.
    Stachlewitz RF; Hart MA; Bettencourt B; Kebede T; Schwartz A; Ratnofsky SE; Calderwood DJ; Waegell WO; Hirst GC
    J Pharmacol Exp Ther; 2005 Oct; 315(1):36-41. PubMed ID: 16014572
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphatidylinositol 3-kinase participates in p56(lck)/CD4-dependent down-regulation of LFA-1-mediated T cell adhesion.
    Mazerolles F; Barbat C; Hivroz C; Fischer A
    J Immunol; 1996 Dec; 157(11):4844-54. PubMed ID: 8943387
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation.
    Shi M; Cooper JC; Yu CL
    Mol Cancer Res; 2006 Jan; 4(1):39-45. PubMed ID: 16446405
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Conversion of p56(lck) to p60(lck) in human peripheral blood T lymphocytes is dependent on co- stimulation through accessory receptors: involvement of phospholipase C, protein kinase C and MAP-kinases in vivo.
    Schröder AJ; Quehl P; Müller J; Samstag Y
    Eur J Immunol; 2000 Feb; 30(2):635-43. PubMed ID: 10671221
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases.
    McRae BL; Wallace C; Dixon KF; Roux A; Mohan S; Jia Y; Presky DH; Tracey DE; Hirst GC
    Int Immunopharmacol; 2005 Apr; 5(4):667-77. PubMed ID: 15710336
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.
    Methi T; Ngai J; Vang T; Torgersen KM; Taskén K
    Eur J Immunol; 2007 Sep; 37(9):2539-48. PubMed ID: 17683112
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Src family kinase activity is required for Kit-mediated mitogen-activated protein (MAP) kinase activation, however loss of functional retinoblastoma protein makes MAP kinase activation unnecessary for growth of small cell lung cancer cells.
    Bondzi C; Litz J; Dent P; Krystal GW
    Cell Growth Differ; 2000 Jun; 11(6):305-14. PubMed ID: 10910097
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.
    DiMauro EF; Newcomb J; Nunes JJ; Bemis JE; Boucher C; Buchanan JL; Buckner WH; Cee VJ; Chai L; Deak HL; Epstein LF; Faust T; Gallant P; Geuns-Meyer SD; Gore A; Gu Y; Henkle B; Hodous BL; Hsieh F; Huang X; Kim JL; Lee JH; Martin MW; Masse CE; McGowan DC; Metz D; Mohn D; Morgenstern KA; Oliveira-dos-Santos A; Patel VF; Powers D; Rose PE; Schneider S; Tomlinson SA; Tudor YY; Turci SM; Welcher AA; White RD; Zhao H; Zhu L; Zhu X
    J Med Chem; 2006 Sep; 49(19):5671-86. PubMed ID: 16970394
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lck tyrosine kinase is important for activation of the CD11a/CD18-integrins in human T lymphocytes.
    Fagerholm S; Hilden TJ; Gahmberg CG
    Eur J Immunol; 2002 Jun; 32(6):1670-8. PubMed ID: 12115650
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.