BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 10910034)

  • 1. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin.
    Thompson WJ; Piazza GA; Li H; Liu L; Fetter J; Zhu B; Sperl G; Ahnen D; Pamukcu R
    Cancer Res; 2000 Jul; 60(13):3338-42. PubMed ID: 10910034
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells.
    Liu L; Li H; Underwood T; Lloyd M; David M; Sperl G; Pamukcu R; Thompson WJ
    J Pharmacol Exp Ther; 2001 Nov; 299(2):583-92. PubMed ID: 11602670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis.
    Piazza GA; Thompson WJ; Pamukcu R; Alila HW; Whitehead CM; Liu L; Fetter JR; Gresh WE; Klein-Szanto AJ; Farnell DR; Eto I; Grubbs CJ
    Cancer Res; 2001 May; 61(10):3961-8. PubMed ID: 11358813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 down-regulation.
    Li H; Liu L; David ML; Whitehead CM; Chen M; Fetter JR; Sperl GJ; Pamukcu R; Thompson WJ
    Biochem Pharmacol; 2002 Nov; 64(9):1325-36. PubMed ID: 12392815
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling.
    Li N; Xi Y; Tinsley HN; Gurpinar E; Gary BD; Zhu B; Li Y; Chen X; Keeton AB; Abadi AH; Moyer MP; Grizzle WE; Chang WC; Clapper ML; Piazza GA
    Mol Cancer Ther; 2013 Sep; 12(9):1848-59. PubMed ID: 23804703
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.
    Whitt JD; Li N; Tinsley HN; Chen X; Zhang W; Li Y; Gary BD; Keeton AB; Xi Y; Abadi AH; Grizzle WE; Piazza GA
    Cancer Prev Res (Phila); 2012 Jun; 5(6):822-33. PubMed ID: 22556201
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
    Pitari GM; Li T; Baksh RI; Waldman SA
    Mol Cancer Ther; 2006 May; 5(5):1190-6. PubMed ID: 16731751
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vasodilator-stimulated phosphoprotein (VASP) phosphorylation provides a biomarker for the action of exisulind and related agents that activate protein kinase G.
    Deguchi A; Soh JW; Li H; Pamukcu R; Thompson WJ; Weinstein IB
    Mol Cancer Ther; 2002 Aug; 1(10):803-9. PubMed ID: 12492113
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.
    Tinsley HN; Gary BD; Keeton AB; Zhang W; Abadi AH; Reynolds RC; Piazza GA
    Mol Cancer Ther; 2009 Dec; 8(12):3331-40. PubMed ID: 19996273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.
    Whitehead CM; Earle KA; Fetter J; Xu S; Hartman T; Chan DC; Zhao TL; Piazza G; Klein-Szanto AJ; Pamukcu R; Alila H; Bunn PA; Thompson WJ
    Mol Cancer Ther; 2003 May; 2(5):479-88. PubMed ID: 12748310
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.
    Deguchi A; Xing SW; Shureiqi I; Yang P; Newman RA; Lippman SM; Feinmark SJ; Oehlen B; Weinstein IB
    Cancer Res; 2005 Sep; 65(18):8442-7. PubMed ID: 16166323
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin-mediated transcription in human breast tumor cells.
    Tinsley HN; Gary BD; Keeton AB; Lu W; Li Y; Piazza GA
    Cancer Prev Res (Phila); 2011 Aug; 4(8):1275-84. PubMed ID: 21505183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.
    Tinsley HN; Gary BD; Thaiparambil J; Li N; Lu W; Li Y; Maxuitenko YY; Keeton AB; Piazza GA
    Cancer Prev Res (Phila); 2010 Oct; 3(10):1303-13. PubMed ID: 20876730
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells.
    Deguchi A; Thompson WJ; Weinstein IB
    Cancer Res; 2004 Jun; 64(11):3966-73. PubMed ID: 15173009
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites.
    Rice PL; Goldberg RJ; Ray EC; Driggers LJ; Ahnen DJ
    Cancer Res; 2001 Feb; 61(4):1541-7. PubMed ID: 11245463
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression and activity of cGMP-dependent phosphodiesterases is up-regulated by lipopolysaccharide (LPS) in rat peritoneal macrophages.
    Witwicka H; Kobiałka M; Siednienko J; Mitkiewicz M; Gorczyca WA
    Biochim Biophys Acta; 2007 Feb; 1773(2):209-18. PubMed ID: 17141339
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potency and mechanism of action of E4021, a type 5 phosphodiesterase isozyme-selective inhibitor, on the photoreceptor phosphodiesterase depend on the state of activation of the enzyme.
    D'Amours MR; Granovsky AE; Artemyev NO; Cote RH
    Mol Pharmacol; 1999 Mar; 55(3):508-14. PubMed ID: 10051534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chemopreventive alteration of the cell-cell adhesion in head and neck squamous cell cancer.
    Naim R; Chang RC; Schultz J; Hormann K
    Oncol Rep; 2006 Aug; 16(2):273-7. PubMed ID: 16820902
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways.
    Rice PL; Peters SL; Beard KS; Ahnen DJ
    Mol Cancer Ther; 2006 Mar; 5(3):746-54. PubMed ID: 16546990
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells.
    Zhu B; Vemavarapu L; Thompson WJ; Strada SJ
    J Cell Biochem; 2005 Feb; 94(2):336-50. PubMed ID: 15526282
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.