BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 10921914)

  • 1. ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.
    Mochida Y; Takeda K; Saitoh M; Nishitoh H; Amagasa T; Ninomiya-Tsuji J; Matsumoto K; Ichijo H
    J Biol Chem; 2000 Oct; 275(42):32747-52. PubMed ID: 10921914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Receptor activator of NF-kappaB ligand (RANKL) activates TAK1 mitogen-activated protein kinase kinase kinase through a signaling complex containing RANK, TAB2, and TRAF6.
    Mizukami J; Takaesu G; Akatsuka H; Sakurai H; Ninomiya-Tsuji J; Matsumoto K; Sakurai N
    Mol Cell Biol; 2002 Feb; 22(4):992-1000. PubMed ID: 11809792
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling.
    Shi L; Zhang Z; Fang S; Xu J; Liu J; Shen J; Fang F; Luo L; Yin Z
    Mol Immunol; 2009 Feb; 46(4):541-50. PubMed ID: 18950863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reciprocal inhibition between the transforming growth factor-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1.
    Kim SY; Shim JH; Chun E; Lee KY
    J Biol Chem; 2012 Jan; 287(5):3381-91. PubMed ID: 22167179
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway.
    Takaesu G; Kishida S; Hiyama A; Yamaguchi K; Shibuya H; Irie K; Ninomiya-Tsuji J; Matsumoto K
    Mol Cell; 2000 Apr; 5(4):649-58. PubMed ID: 10882101
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaB.
    Lee SW; Han SI; Kim HH; Lee ZH
    J Biochem Mol Biol; 2002 Jul; 35(4):371-6. PubMed ID: 12296995
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Thioredoxin inhibits tumor necrosis factor- or interleukin-1-induced NF-kappaB activation at a level upstream of NF-kappaB-inducing kinase.
    Takeuchi J; Hirota K; Itoh T; Shinkura R; Kitada K; Yodoi J; Namba T; Fukuda K
    Antioxid Redox Signal; 2000; 2(1):83-92. PubMed ID: 11232604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol.
    Jiang Z; Ninomiya-Tsuji J; Qian Y; Matsumoto K; Li X
    Mol Cell Biol; 2002 Oct; 22(20):7158-67. PubMed ID: 12242293
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway.
    Ninomiya-Tsuji J; Kishimoto K; Hiyama A; Inoue J; Cao Z; Matsumoto K
    Nature; 1999 Mar; 398(6724):252-6. PubMed ID: 10094049
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The MAPK kinase kinase TAK1 plays a central role in coupling the interleukin-1 receptor to both transcriptional and RNA-targeted mechanisms of gene regulation.
    Holtmann H; Enninga J; Kalble S; Thiefes A; Dorrie A; Broemer M; Winzen R; Wilhelm A; Ninomiya-Tsuji J; Matsumoto K; Resch K; Kracht M
    J Biol Chem; 2001 Feb; 276(5):3508-16. PubMed ID: 11050078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1-mediated NF-kappa B and AP-1 activation.
    Funakoshi M; Sonoda Y; Tago K; Tominaga S; Kasahara T
    Int Immunopharmacol; 2001 Mar; 1(3):595-604. PubMed ID: 11367542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo.
    Shim JH; Xiao C; Paschal AE; Bailey ST; Rao P; Hayden MS; Lee KY; Bussey C; Steckel M; Tanaka N; Yamada G; Akira S; Matsumoto K; Ghosh S
    Genes Dev; 2005 Nov; 19(22):2668-81. PubMed ID: 16260493
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide-dependent kinase-1 inhibits TRAF6 ubiquitination by interrupting the formation of TAK1-TAB2 complex in TLR4 signaling.
    Moon G; Kim J; Min Y; Wi SM; Shim JH; Chun E; Lee KY
    Cell Signal; 2015 Dec; 27(12):2524-33. PubMed ID: 26432169
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential roles of ASK1 and TAK1 in Helicobacter pylori-induced cellular responses.
    Hayakawa Y; Hirata Y; Kinoshita H; Sakitani K; Nakagawa H; Nakata W; Takahashi R; Sakamoto K; Maeda S; Koike K
    Infect Immun; 2013 Dec; 81(12):4551-60. PubMed ID: 24082073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TRAF6 and TAK1 Contribute to SAMHD1-Mediated Negative Regulation of NF-κB Signaling.
    Espada CE; St Gelais C; Bonifati S; Maksimova VV; Cahill MP; Kim SH; Wu L
    J Virol; 2021 Jan; 95(3):. PubMed ID: 33177202
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling.
    Yamazaki K; Gohda J; Kanayama A; Miyamoto Y; Sakurai H; Yamamoto M; Akira S; Hayashi H; Su B; Inoue J
    Sci Signal; 2009 Oct; 2(93):ra66. PubMed ID: 19843958
    [TBL] [Abstract][Full Text] [Related]  

  • 17. WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-kappaB activation pathway.
    Gao D; Wang R; Li B; Yang Y; Zhai Z; Chen DY
    Cell Mol Life Sci; 2009 Aug; 66(15):2573-84. PubMed ID: 19521662
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Euscaphic acid isolated from roots of Rosa rugosa inhibits LPS-induced inflammatory responses via TLR4-mediated NF-κB inactivation in RAW 264.7 macrophages.
    Kim IT; Ryu S; Shin JS; Choi JH; Park HJ; Lee KT
    J Cell Biochem; 2012 Jun; 113(6):1936-46. PubMed ID: 22234926
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K; Kobayashi N; Inazawa Y; Zhang H; Nishitoh H; Ichijo H; Saeki K; Isemura M; Yuo A
    Biochem J; 2002 Dec; 368(Pt 3):705-20. PubMed ID: 12206715
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MiR-345-3p attenuates apoptosis and inflammation caused by oxidized low-density lipoprotein by targeting TRAF6 via TAK1/p38/NF-kB signaling in endothelial cells.
    Wei Q; Tu Y; Zuo L; Zhao J; Chang Z; Zou Y; Qiu J
    Life Sci; 2020 Jan; 241():117142. PubMed ID: 31825793
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.