BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 10921923)

  • 1. Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization.
    Wu K; Chen A; Pan ZQ
    J Biol Chem; 2000 Oct; 275(41):32317-24. PubMed ID: 10921923
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation.
    Wu K; Fuchs SY; Chen A; Tan P; Gomez C; Ronai Z; Pan ZQ
    Mol Cell Biol; 2000 Feb; 20(4):1382-93. PubMed ID: 10648623
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1.
    Furukawa M; Zhang Y; McCarville J; Ohta T; Xiong Y
    Mol Cell Biol; 2000 Nov; 20(21):8185-97. PubMed ID: 11027288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability.
    Morimoto M; Nishida T; Nagayama Y; Yasuda H
    Biochem Biophys Res Commun; 2003 Feb; 301(2):392-8. PubMed ID: 12565873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34.
    Wu K; Chen A; Tan P; Pan ZQ
    J Biol Chem; 2002 Jan; 277(1):516-27. PubMed ID: 11675391
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts.
    Wirbelauer C; Sutterlüty H; Blondel M; Gstaiger M; Peter M; Reymond F; Krek W
    EMBO J; 2000 Oct; 19(20):5362-75. PubMed ID: 11032804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NEDD8 recruits E2-ubiquitin to SCF E3 ligase.
    Kawakami T; Chiba T; Suzuki T; Iwai K; Yamanaka K; Minato N; Suzuki H; Shimbara N; Hidaka Y; Osaka F; Omata M; Tanaka K
    EMBO J; 2001 Aug; 20(15):4003-12. PubMed ID: 11483504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro ubiquitination of cyclin D1 by ROC1-CUL1 and ROC1-CUL3.
    Maeda I; Ohta T; Koizumi H; Fukuda M
    FEBS Lett; 2001 Apr; 494(3):181-5. PubMed ID: 11311237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.
    Tan P; Fuchs SY; Chen A; Wu K; Gomez C; Ronai Z; Pan ZQ
    Mol Cell; 1999 Apr; 3(4):527-33. PubMed ID: 10230406
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4.
    Strack P; Caligiuri M; Pelletier M; Boisclair M; Theodoras A; Beer-Romero P; Glass S; Parsons T; Copeland RA; Auger KR; Benfield P; Brizuela L; Rolfe M
    Oncogene; 2000 Jul; 19(31):3529-36. PubMed ID: 10918611
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail.
    Yamoah K; Oashi T; Sarikas A; Gazdoiu S; Osman R; Pan ZQ
    Proc Natl Acad Sci U S A; 2008 Aug; 105(34):12230-5. PubMed ID: 18723677
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The conserved RING-H2 finger of ROC1 is required for ubiquitin ligation.
    Chen A; Wu K; Fuchs SY; Tan P; Gomez C; Pan ZQ
    J Biol Chem; 2000 May; 275(20):15432-9. PubMed ID: 10748083
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha.
    Read MA; Brownell JE; Gladysheva TB; Hottelet M; Parent LA; Coggins MB; Pierce JW; Podust VN; Luo RS; Chau V; Palombella VJ
    Mol Cell Biol; 2000 Apr; 20(7):2326-33. PubMed ID: 10713156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.
    Liu J; Furukawa M; Matsumoto T; Xiong Y
    Mol Cell; 2002 Dec; 10(6):1511-8. PubMed ID: 12504025
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
    Ohta T; Michel JJ; Schottelius AJ; Xiong Y
    Mol Cell; 1999 Apr; 3(4):535-41. PubMed ID: 10230407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination.
    Podust VN; Brownell JE; Gladysheva TB; Luo RS; Wang C; Coggins MB; Pierce JW; Lightcap ES; Chau V
    Proc Natl Acad Sci U S A; 2000 Apr; 97(9):4579-84. PubMed ID: 10781063
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).
    Morimoto M; Nishida T; Honda R; Yasuda H
    Biochem Biophys Res Commun; 2000 Apr; 270(3):1093-6. PubMed ID: 10772955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of processing of the NF-kappa B2 p100 precursor: identification of the specific polyubiquitin chain-anchoring lysine residue and analysis of the role of NEDD8-modification on the SCF(beta-TrCP) ubiquitin ligase.
    Amir RE; Haecker H; Karin M; Ciechanover A
    Oncogene; 2004 Apr; 23(14):2540-7. PubMed ID: 14676825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases.
    Goldenberg SJ; Cascio TC; Shumway SD; Garbutt KC; Liu J; Xiong Y; Zheng N
    Cell; 2004 Nov; 119(4):517-28. PubMed ID: 15537541
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
    Kim AY; Bommeljé CC; Lee BE; Yonekawa Y; Choi L; Morris LG; Huang G; Kaufman A; Ryan RJ; Hao B; Ramanathan Y; Singh B
    J Biol Chem; 2008 Nov; 283(48):33211-20. PubMed ID: 18826954
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.