BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 10933827)

  • 1. Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: understanding precursor effects.
    Leaf T; Cadapan L; Carreras C; Regentin R; Ou S; Woo E; Ashley G; Licari P
    Biotechnol Prog; 2000; 16(4):553-6. PubMed ID: 10933827
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combining classical, genetic, and process strategies for improved precursor-directed production of 6-deoxyerythronolide B analogues.
    Desai RP; Leaf T; Hu Z; Hutchinson CR; Hong A; Byng G; Galazzo J; Licari P
    Biotechnol Prog; 2004; 20(1):38-43. PubMed ID: 14763821
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemobiosynthesis of novel 6-deoxyerythronolide B analogues by mutation of the loading module of 6-deoxyerythronolide B synthase 1.
    Murli S; MacMillan KS; Hu Z; Ashley GW; Dong SD; Kealey JT; Reeves CD; Kennedy J
    Appl Environ Microbiol; 2005 Aug; 71(8):4503-9. PubMed ID: 16085842
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase.
    Ward SL; Desai RP; Hu Z; Gramajo H; Katz L
    J Ind Microbiol Biotechnol; 2007 Jan; 34(1):9-15. PubMed ID: 17033784
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Precursor-directed production of erythromycin analogs by Saccharopolyspora erythraea.
    Frykman S; Leaf T; Carreras C; Licari P
    Biotechnol Bioeng; 2001 Dec; 76(4):303-10. PubMed ID: 11745157
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Saccharopolyspora erythraea-catalyzed bioconversion of 6-deoxyerythronolide B analogs for production of novel erythromycins.
    Carreras C; Frykman S; Ou S; Cadapan L; Zavala S; Woo E; Leaf T; Carney J; Burlingame M; Patel S; Ashley G; Licari P
    J Biotechnol; 2002 Jan; 92(3):217-28. PubMed ID: 11689246
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of domains within megalomicin and erythromycin polyketide synthase modules responsible for differences in polyketide production levels in Escherichia coli.
    Murli S; Piagentini M; McDaniel R; Hutchinson CR
    Biochemistry; 2004 Dec; 43(50):15884-90. PubMed ID: 15595843
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Precursor-directed biosynthesis of 16-membered macrolides by the erythromycin polyketide synthase.
    Kinoshita K; Williard PG; Khosla C; Cane DE
    J Am Chem Soc; 2001 Mar; 123(11):2495-502. PubMed ID: 11456917
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Precursor-directed biosynthesis of novel triketide lactones.
    Regentin R; Kennedy J; Wu N; Carney JR; Licari P; Galazzo J; Desai R
    Biotechnol Prog; 2004; 20(1):122-7. PubMed ID: 14763833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Erythromycin biosynthesis: kinetic studies on a fully active modular polyketide synthase using natural and unnatural substrates.
    Pieper R; Ebert-Khosla S; Cane D; Khosla C
    Biochemistry; 1996 Feb; 35(7):2054-60. PubMed ID: 8652546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 6-Deoxyerythronolide B analogue production in Escherichia coli through metabolic pathway engineering.
    Kennedy J; Murli S; Kealey JT
    Biochemistry; 2003 Dec; 42(48):14342-8. PubMed ID: 14640703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell-free synthesis of polyketides by recombinant erythromycin polyketide synthases.
    Pieper R; Luo G; Cane DE; Khosla C
    Nature; 1995 Nov; 378(6554):263-6. PubMed ID: 7477343
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Precursor-directed biosynthesis of 12-ethyl erythromycin.
    Jacobsen JR; Keatinge-Clay AT; Cane DE; Khosla C
    Bioorg Med Chem; 1998 Aug; 6(8):1171-7. PubMed ID: 9784859
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of a high cell-density fed-batch bioprocess for the heterologous production of 6-deoxyerythronolide B in Escherichia coli.
    Lau J; Tran C; Licari P; Galazzo J
    J Biotechnol; 2004 May; 110(1):95-103. PubMed ID: 15099909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preparation of erythromycin analogs having functional groups at C-15.
    Ashley GW; Burlingame M; Desai R; Fu H; Leaf T; Licari PJ; Tran C; Abbanat D; Bush K; Macielag M
    J Antibiot (Tokyo); 2006 Jul; 59(7):392-401. PubMed ID: 17025015
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase.
    Jacobsen JR; Hutchinson CR; Cane DE; Khosla C
    Science; 1997 Jul; 277(5324):367-9. PubMed ID: 9219693
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improving heterologous polyketide production in Escherichia coli by overexpression of an S-adenosylmethionine synthetase gene.
    Wang Y; Boghigian BA; Pfeifer BA
    Appl Microbiol Biotechnol; 2007 Nov; 77(2):367-73. PubMed ID: 17876579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Erythromycin biosynthesis. Highly efficient incorporation of polyketide chain elongation intermediates into 6-deoxyerythronolide B in an engineered Streptomyces host.
    Cane DE; Luo G; Khosla C; Kao CM; Katz L
    J Antibiot (Tokyo); 1995 Jul; 48(7):647-51. PubMed ID: 7649863
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Towards a characterization of the structural determinants of specificity in the macrocyclizing thioesterase for deoxyerythronolide B biosynthesis.
    Argyropoulos P; Bergeret F; Pardin C; Reimer JM; Pinto A; Boddy CN; Schmeing TM
    Biochim Biophys Acta; 2016 Mar; 1860(3):486-97. PubMed ID: 26592346
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Erythromycin biosynthesis: exploiting the catalytic versatility of the modular polyketide synthase.
    Luo G; Pieper R; Rosa A; Khosla C; Cane DE
    Bioorg Med Chem; 1996 Jul; 4(7):995-9. PubMed ID: 8831969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.