These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

357 related articles for article (PubMed ID: 10939589)

  • 1. The heat shock protein 90 antagonist geldanamycin alters chaperone association with p210bcr-abl and v-src proteins before their degradation by the proteasome.
    An WG; Schulte TW; Neckers LM
    Cell Growth Differ; 2000 Jul; 11(7):355-60. PubMed ID: 10939589
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Geldanamycin and its analogue 17-allylamino-17-demethoxygeldanamycin lowers Bcr-Abl levels and induces apoptosis and differentiation of Bcr-Abl-positive human leukemic blasts.
    Nimmanapalli R; O'Bryan E; Bhalla K
    Cancer Res; 2001 Mar; 61(5):1799-804. PubMed ID: 11280726
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel oxime derivatives of radicicol induce erythroid differentiation associated with preferential G(1) phase accumulation against chronic myelogenous leukemia cells through destabilization of Bcr-Abl with Hsp90 complex.
    Shiotsu Y; Neckers LM; Wortman I; An WG; Schulte TW; Soga S; Murakata C; Tamaoki T; Akinaga S
    Blood; 2000 Sep; 96(6):2284-91. PubMed ID: 10979978
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of geldanamycin, a heat-shock protein 90-binding agent, on T cell function and T cell nonreceptor protein tyrosine kinases.
    Yorgin PD; Hartson SD; Fellah AM; Scroggins BT; Huang W; Katsanis E; Couchman JM; Matts RL; Whitesell L
    J Immunol; 2000 Mar; 164(6):2915-23. PubMed ID: 10706677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent.
    Whitesell L; Sutphin PD; Pulcini EJ; Martinez JD; Cook PH
    Mol Cell Biol; 1998 Mar; 18(3):1517-24. PubMed ID: 9488468
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.
    Whitesell L; Mimnaugh EG; De Costa B; Myers CE; Neckers LM
    Proc Natl Acad Sci U S A; 1994 Aug; 91(18):8324-8. PubMed ID: 8078881
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A cell-based screen for inhibitors of protein folding and degradation.
    Boschelli F; Golas JM; Petersen R; Lau V; Chen L; Tkach D; Zhao Q; Fruhling DS; Liu H; Nam C; Arndt KT
    Cell Stress Chaperones; 2010 Nov; 15(6):913-27. PubMed ID: 20717760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Geldanamycin-induced destabilization of Raf-1 involves the proteasome.
    Schulte TW; An WG; Neckers LM
    Biochem Biophys Res Commun; 1997 Oct; 239(3):655-9. PubMed ID: 9367823
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome.
    Loo MA; Jensen TJ; Cui L; Hou Y; Chang XB; Riordan JR
    EMBO J; 1998 Dec; 17(23):6879-87. PubMed ID: 9843494
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin.
    Wu LX; Xu JH; Zhang KZ; Lin Q; Huang XW; Wen CX; Chen YZ
    Leukemia; 2008 Jul; 22(7):1402-9. PubMed ID: 18418407
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Caspase-dependent, geldanamycin-enhanced cleavage of co-chaperone p23 in leukemic apoptosis.
    Gausdal G; Gjertsen BT; Fladmark KE; Demol H; Vandekerckhove J; Døskeland SO
    Leukemia; 2004 Dec; 18(12):1989-96. PubMed ID: 15483679
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ubiquitination and proteasomal degradation of nucleophosmin-anaplastic lymphoma kinase induced by 17-allylamino-demethoxygeldanamycin: role of the co-chaperone carboxyl heat shock protein 70-interacting protein.
    Bonvini P; Dalla Rosa H; Vignes N; Rosolen A
    Cancer Res; 2004 May; 64(9):3256-64. PubMed ID: 15126367
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of geldanamycin on the kinetics of chaperone-mediated renaturation of firefly luciferase in rabbit reticulocyte lysate.
    Thulasiraman V; Matts RL
    Biochemistry; 1996 Oct; 35(41):13443-50. PubMed ID: 8873613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90.
    Goasduff T; Cederbaum AI
    Arch Biochem Biophys; 2000 Jul; 379(2):321-30. PubMed ID: 10898951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Labeling of v-Src and BCR-ABL tyrosine kinases with [14C]herbimycin A and its use in the elucidation of the kinase inactivation mechanism.
    Fukazawa H; Uehara Y; Murakami Y; Mizuno S; Hamada M; Takeuchi T
    FEBS Lett; 1994 Mar; 340(3):155-8. PubMed ID: 8131836
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzoquinoid ansamycins (herbimycin A and geldanamycin) interfere with the maturation of growth factor receptor tyrosine kinases.
    Sakagami M; Morrison P; Welch WJ
    Cell Stress Chaperones; 1999 Mar; 4(1):19-28. PubMed ID: 10467105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily.
    Miyata Y; Ikawa Y; Shibuya M; Nishida E
    J Biol Chem; 2001 Jun; 276(24):21841-8. PubMed ID: 11278794
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Progesterone receptor deficient in chromatin binding has an altered cellular state.
    Botos J; Xian W; Smith DF; Smith CL
    J Biol Chem; 2004 Apr; 279(15):15231-9. PubMed ID: 14744870
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin.
    Schulte TW; Neckers LM
    Cancer Chemother Pharmacol; 1998; 42(4):273-9. PubMed ID: 9744771
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase.
    Ochel HJ; Schulte TW; Nguyen P; Trepel J; Neckers L
    Mol Genet Metab; 1999 Jan; 66(1):24-30. PubMed ID: 9973544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.