These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases. Yao Q; Nishiuchi R; Li Q; Kumar AR; Hudson WA; Kersey JH Clin Cancer Res; 2003 Oct; 9(12):4483-93. PubMed ID: 14555522 [TBL] [Abstract][Full Text] [Related]
23. Degradation of heterotrimeric Galpha(o) subunits via the proteosome pathway is induced by the hsp90-specific compound geldanamycin. Busconi L; Guan J; Denker BM J Biol Chem; 2000 Jan; 275(3):1565-9. PubMed ID: 10636845 [TBL] [Abstract][Full Text] [Related]
24. Natural product origins of Hsp90 inhibitors. Uehara Y Curr Cancer Drug Targets; 2003 Oct; 3(5):325-30. PubMed ID: 14529384 [TBL] [Abstract][Full Text] [Related]
25. HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells. Rao R; Fiskus W; Yang Y; Lee P; Joshi R; Fernandez P; Mandawat A; Atadja P; Bradner JE; Bhalla K Blood; 2008 Sep; 112(5):1886-93. PubMed ID: 18591380 [TBL] [Abstract][Full Text] [Related]
26. Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins. Bohen SP Mol Cell Biol; 1998 Jun; 18(6):3330-9. PubMed ID: 9584173 [TBL] [Abstract][Full Text] [Related]
27. Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation. Yun BG; Matts RL Exp Cell Res; 2005 Jul; 307(1):212-23. PubMed ID: 15922741 [TBL] [Abstract][Full Text] [Related]
28. Molecular characterization and sensitivity of STI-571 (imatinib mesylate, Gleevec)-resistant, Bcr-Abl-positive, human acute leukemia cells to SRC kinase inhibitor PD180970 and 17-allylamino-17-demethoxygeldanamycin. Nimmanapalli R; O'Bryan E; Huang M; Bali P; Burnette PK; Loughran T; Tepperberg J; Jove R; Bhalla K Cancer Res; 2002 Oct; 62(20):5761-9. PubMed ID: 12384536 [TBL] [Abstract][Full Text] [Related]
29. Geldanamycin induces heat shock protein expression through activation of HSF1 in K562 erythroleukemic cells. Kim HR; Kang HS; Kim HD IUBMB Life; 1999 Oct; 48(4):429-33. PubMed ID: 10632574 [TBL] [Abstract][Full Text] [Related]
30. Kinase-addiction and bi-phasic sensitivity-resistance of Bcr-Abl- and Raf-1-expressing cells to imatinib and geldanamycin. Demidenko ZN; An WG; Lee JT; Romanova LY; McCubrey JA; Blagosklonny MV Cancer Biol Ther; 2005 Apr; 4(4):484-90. PubMed ID: 15846067 [TBL] [Abstract][Full Text] [Related]
31. The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase. Stancato LF; Silverstein AM; Owens-Grillo JK; Chow YH; Jove R; Pratt WB J Biol Chem; 1997 Feb; 272(7):4013-20. PubMed ID: 9020108 [TBL] [Abstract][Full Text] [Related]
32. G protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. Luo J; Benovic JL J Biol Chem; 2003 Dec; 278(51):50908-14. PubMed ID: 14557268 [TBL] [Abstract][Full Text] [Related]
33. Retrograde transport of the glucocorticoid receptor in neurites requires dynamic assembly of complexes with the protein chaperone hsp90 and is linked to the CHIP component of the machinery for proteasomal degradation. Galigniana MD; Harrell JM; Housley PR; Patterson C; Fisher SK; Pratt WB Brain Res Mol Brain Res; 2004 Apr; 123(1-2):27-36. PubMed ID: 15046863 [TBL] [Abstract][Full Text] [Related]
34. Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells. Whitesell L; Cook P Mol Endocrinol; 1996 Jun; 10(6):705-12. PubMed ID: 8776730 [TBL] [Abstract][Full Text] [Related]
35. Binding of p23 and hsp90 during assembly with the progesterone receptor. Johnson JL; Toft DO Mol Endocrinol; 1995 Jun; 9(6):670-8. PubMed ID: 8592513 [TBL] [Abstract][Full Text] [Related]
36. Activation of Src kinases p53/56lyn and p59hck by p210bcr/abl in myeloid cells. Danhauser-Riedl S; Warmuth M; Druker BJ; Emmerich B; Hallek M Cancer Res; 1996 Aug; 56(15):3589-96. PubMed ID: 8758931 [TBL] [Abstract][Full Text] [Related]
37. Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability. Boudeau J; Deak M; Lawlor MA; Morrice NA; Alessi DR Biochem J; 2003 Mar; 370(Pt 3):849-57. PubMed ID: 12489981 [TBL] [Abstract][Full Text] [Related]
38. The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin. Segnitz B; Gehring U J Biol Chem; 1997 Jul; 272(30):18694-701. PubMed ID: 9228040 [TBL] [Abstract][Full Text] [Related]
39. Binding of immunophilins to the 90 kDa heat shock protein (hsp90) via a tetratricopeptide repeat domain is a conserved protein interaction in plants. Owens-Grillo JK; Stancato LF; Hoffmann K; Pratt WB; Krishna P Biochemistry; 1996 Dec; 35(48):15249-55. PubMed ID: 8952474 [TBL] [Abstract][Full Text] [Related]
40. Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents. Miyata Y Curr Pharm Des; 2005; 11(9):1131-8. PubMed ID: 15853661 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]