BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 10941801)

  • 1. Expression and characterization of E. coli-produced soluble, functional human dihydroorotate dehydrogenase: a potential target for immunosuppression.
    Neidhardt EA; Punreddy SR; McLean JE; Hedstrom L; Grossman TH
    J Mol Microbiol Biotechnol; 1999 Aug; 1(1):183-8. PubMed ID: 10941801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression, purification, and characterization of histidine-tagged rat and human flavoenzyme dihydroorotate dehydrogenase.
    Bader B; Knecht W; Fries M; Löffler M
    Protein Expr Purif; 1998 Aug; 13(3):414-22. PubMed ID: 9693067
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rat dihydroorotate dehydrogenase: isolation of the recombinant enzyme from mitochondria of insect cells.
    Knecht W; Altekruse D; Rotgeri A; Gonski S; Löffler M
    Protein Expr Purif; 1997 Jun; 10(1):89-99. PubMed ID: 9179295
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A second dihydroorotate dehydrogenase (Type A) of the human pathogen Enterococcus faecalis: expression, purification, and steady-state kinetic mechanism.
    Marcinkeviciene J; Jiang W; Locke G; Kopcho LM; Rogers MJ; Copeland RA
    Arch Biochem Biophys; 2000 May; 377(1):178-86. PubMed ID: 10775458
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recombinant human dihydroorotate dehydrogenase: expression, purification, and characterization of a catalytically functional truncated enzyme.
    Copeland RA; Davis JP; Dowling RL; Lombardo D; Murphy KB; Patterson TA
    Arch Biochem Biophys; 1995 Oct; 323(1):79-86. PubMed ID: 7487077
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction.
    Inaoka DK; Sakamoto K; Shimizu H; Shiba T; Kurisu G; Nara T; Aoki T; Kita K; Harada S
    Biochemistry; 2008 Oct; 47(41):10881-91. PubMed ID: 18808149
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase.
    McLean JE; Neidhardt EA; Grossman TH; Hedstrom L
    Biochemistry; 2001 Feb; 40(7):2194-200. PubMed ID: 11329288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cloning, expression, purification, and characterization of Leishmania major dihydroorotate dehydrogenase.
    Feliciano PR; Cordeiro AT; Costa-Filho AJ; Nonato MC
    Protein Expr Purif; 2006 Jul; 48(1):98-103. PubMed ID: 16600626
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified recombinant enzyme.
    Knecht W; Bergjohann U; Gonski S; Kirschbaum B; Löffler M
    Eur J Biochem; 1996 Aug; 240(1):292-301. PubMed ID: 8925840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recombinant expression of N-terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase. A versatile tool to rate inhibitor effects?
    Ullrich A; Knecht W; Fries M; Löffler M
    Eur J Biochem; 2001 Mar; 268(6):1861-8. PubMed ID: 11248707
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis.
    Björnberg O; Jordan DB; Palfey BA; Jensen KF
    Arch Biochem Biophys; 2001 Jul; 391(2):286-94. PubMed ID: 11437361
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of dihydroorotate dehydrogenase activity by brequinar sodium.
    Chen SF; Perrella FW; Behrens DL; Papp LM
    Cancer Res; 1992 Jul; 52(13):3521-7. PubMed ID: 1617622
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Active site of dihydroorotate dehydrogenase A from Lactococcus lactis investigated by chemical modification and mutagenesis.
    Björnberg O; Rowland P; Larsen S; Jensen KF
    Biochemistry; 1997 Dec; 36(51):16197-205. PubMed ID: 9405053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.
    Walse B; Dufe VT; Svensson B; Fritzson I; Dahlberg L; Khairoullina A; Wellmar U; Al-Karadaghi S
    Biochemistry; 2008 Aug; 47(34):8929-36. PubMed ID: 18672895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity.
    Baldwin J; Farajallah AM; Malmquist NA; Rathod PK; Phillips MA
    J Biol Chem; 2002 Nov; 277(44):41827-34. PubMed ID: 12189151
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drosophila melanogaster dihydroorotate dehydrogenase: the N-terminus is important for biological function in vivo but not for catalytic properties in vitro.
    Löffler M; Knecht W; Rawls J; Ullrich A; Dietz C
    Insect Biochem Mol Biol; 2002 Sep; 32(9):1159-69. PubMed ID: 12213251
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases.
    Fagan RL; Nelson MN; Pagano PM; Palfey BA
    Biochemistry; 2006 Dec; 45(50):14926-32. PubMed ID: 17154530
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives.
    Knecht W; Löffler M
    Biochem Pharmacol; 1998 Nov; 56(9):1259-64. PubMed ID: 9802339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insight into the chemistry of flavin reduction and oxidation in Escherichia coli dihydroorotate dehydrogenase obtained by rapid reaction studies.
    Palfey BA; Björnberg O; Jensen KF
    Biochemistry; 2001 Apr; 40(14):4381-90. PubMed ID: 11284694
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site directed spin labeling studies of Escherichia coli dihydroorotate dehydrogenase N-terminal extension.
    Couto SG; Cristina Nonato M; Costa-Filho AJ
    Biochem Biophys Res Commun; 2011 Oct; 414(3):487-92. PubMed ID: 21986535
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.