BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 10945319)

  • 41. Phenotyping CYP3A using midazolam in cancer and noncancer Asian patients.
    Lee HS; Goh BC; Fan L; Khoo YM; Wang L; Lim R; Ong AB; Chua C
    Br J Clin Pharmacol; 2003 Mar; 55(3):270-7. PubMed ID: 12630977
    [TBL] [Abstract][Full Text] [Related]  

  • 42. An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A).
    Palmer JL; Scott RJ; Gibson A; Dickins M; Pleasance S
    Br J Clin Pharmacol; 2001 Nov; 52(5):555-61. PubMed ID: 11736864
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics.
    Liangpunsakul S; Kolwankar D; Pinto A; Gorski JC; Hall SD; Chalasani N
    Hepatology; 2005 May; 41(5):1144-50. PubMed ID: 15841467
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Disposition and miotic effects of oral alfentanil: a potential noninvasive probe for first-pass cytochrome P4503A activity.
    Kharasch ED; Hoffer C; Walker A; Sheffels P
    Clin Pharmacol Ther; 2003 Mar; 73(3):199-208. PubMed ID: 12621385
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
    Lepper ER; Baker SD; Permenter M; Ries N; van Schaik RH; Schenk PW; Price DK; Ahn D; Smith NF; Cusatis G; Ingersoll RG; Bates SE; Mathijssen RH; Verweij J; Figg WD; Sparreboom A
    Clin Cancer Res; 2005 Oct; 11(20):7398-404. PubMed ID: 16243813
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Open-label, nonrandomized study of the effects of gatifloxacin on the pharmacokinetics of midazolam in healthy male volunteers.
    Grasela DM; LaCreta FP; Kollia GD; Randall DM; Uderman HD
    Pharmacotherapy; 2000 Mar; 20(3):330-5. PubMed ID: 10730688
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Genotype of CYP3AP1 associated with CYP3A activity in Chinese Han population.
    Zhu B; Chen GL; Chen XP; He N; Liu ZQ; Jiang CH; Wang D; Zhou HH
    Acta Pharmacol Sin; 2002 Jun; 23(6):567-72. PubMed ID: 12060534
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects.
    Darwish M; Kirby M; Robertson P; Hellriegel ET
    Clin Pharmacokinet; 2008; 47(1):61-74. PubMed ID: 18076219
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Single plasma sampling to predict oral clearance of CYP3A probe midazolam.
    Zhu B; Ou-Yang DS; Cheng ZN; Huang SL; Zhou HH
    Acta Pharmacol Sin; 2001 Jul; 22(7):634-8. PubMed ID: 11749829
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice.
    Greenblatt DJ; von Moltke LL; Harmatz JS; Chen G; Weemhoff JL; Jen C; Kelley CJ; LeDuc BW; Zinny MA
    Clin Pharmacol Ther; 2003 Aug; 74(2):121-9. PubMed ID: 12891222
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers.
    Yeh RF; Gaver VE; Patterson KB; Rezk NL; Baxter-Meheux F; Blake MJ; Eron JJ; Klein CE; Rublein JC; Kashuba AD
    J Acquir Immune Defic Syndr; 2006 May; 42(1):52-60. PubMed ID: 16639344
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Prediction of cyclosporine clearance in liver transplant recipients by the use of midazolam as a cytochrome P450 3A probe.
    Villeneuve JP; L'Ecuyer L; De Maeght S; Bannon P
    Clin Pharmacol Ther; 2000 Mar; 67(3):242-8. PubMed ID: 10741627
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism.
    Paine MF; Khalighi M; Fisher JM; Shen DD; Kunze KL; Marsh CL; Perkins JD; Thummel KE
    J Pharmacol Exp Ther; 1997 Dec; 283(3):1552-62. PubMed ID: 9400033
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries.
    van Dyk M; Marshall JC; Sorich MJ; Wood LS; Rowland A
    Eur J Clin Pharmacol; 2018 Jul; 74(7):913-920. PubMed ID: 29572563
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populations.
    Schirmer M; Toliat MR; Haberl M; Suk A; Kamdem LK; Klein K; Brockmöller J; Nürnberg P; Zanger UM; Wojnowski L
    Pharmacogenet Genomics; 2006 Jan; 16(1):59-71. PubMed ID: 16344723
    [TBL] [Abstract][Full Text] [Related]  

  • 56. In-vivo and in-vitro metabolic clearance of midazolam, a cytochrome P450 3A substrate, by the liver under normal and increased enzyme activity in rats.
    Higashikawa F; Murakami T; Kaneda T; Takano M
    J Pharm Pharmacol; 1999 Apr; 51(4):405-10. PubMed ID: 10385212
    [TBL] [Abstract][Full Text] [Related]  

  • 57. CYP3A4-V and prostate cancer in African Americans: causal or confounding association because of population stratification?
    Kittles RA; Chen W; Panguluri RK; Ahaghotu C; Jackson A; Adebamowo CA; Griffin R; Williams T; Ukoli F; Adams-Campbell L; Kwagyan J; Isaacs W; Freeman V; Dunston GM
    Hum Genet; 2002 Jun; 110(6):553-60. PubMed ID: 12107441
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug-drug interaction model rats.
    Kanazu T; Okamura N; Yamaguchi Y; Baba T; Koike M
    Xenobiotica; 2005 Apr; 35(4):305-17. PubMed ID: 16019953
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Associations of the CYP3A5*3 and CYP3A4*1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese.
    Chan SW; Xiao Y; Hu M; Yin OQ; Chu TT; Fok BS; Lee VH; Tomlinson B
    J Clin Pharm Ther; 2016 Oct; 41(5):552-8. PubMed ID: 27511886
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Cisapride: a potential model substrate to assess cytochrome P4503A4 activity in vivo.
    Lowry JA; Kearns GL; Abdel-Rahman SM; Nafziger AN; Khan IS; Kashuba AD; Schuetz EG; Bertino JS; van den Anker JN; Leeder JS
    Clin Pharmacol Ther; 2003 Mar; 73(3):209-22. PubMed ID: 12621386
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.