180 related articles for article (PubMed ID: 10948191)
1. An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling.
Small KM; Forbes SL; Brown KM; Liggett SB
J Biol Chem; 2000 Dec; 275(49):38518-23. PubMed ID: 10948191
[TBL] [Abstract][Full Text] [Related]
2. Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch.
Liang M; Freedman NJ; Theiss CT; Liggett SB
Biochemistry; 2001 Dec; 40(49):15031-7. PubMed ID: 11732925
[TBL] [Abstract][Full Text] [Related]
3. A four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectors.
Small KM; Forbes SL; Rahman FF; Bridges KM; Liggett SB
J Biol Chem; 2000 Jul; 275(30):23059-64. PubMed ID: 10801795
[TBL] [Abstract][Full Text] [Related]
4. Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s).
Brink CB; Wade SM; Neubig RR
J Pharmacol Exp Ther; 2000 Aug; 294(2):539-47. PubMed ID: 10900230
[TBL] [Abstract][Full Text] [Related]
5. Role of the amino terminus of the third intracellular loop in agonist-promoted downregulation of the alpha2A-adrenergic receptor.
Jewell-Motz EA; Donnelly ET; Eason MG; Liggett SB
Biochemistry; 1997 Jul; 36(29):8858-63. PubMed ID: 9220972
[TBL] [Abstract][Full Text] [Related]
6. Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling.
Eason MG; Liggett SB
J Biol Chem; 1995 Oct; 270(42):24753-60. PubMed ID: 7559592
[TBL] [Abstract][Full Text] [Related]
7. An acidic motif within the third intracellular loop of the alpha2C2 adrenergic receptor is required for agonist-promoted phosphorylation and desensitization.
Jewell-Motz EA; Liggett SB
Biochemistry; 1995 Sep; 34(37):11946-53. PubMed ID: 7547931
[TBL] [Abstract][Full Text] [Related]
8. Four consecutive serines in the third intracellular loop are the sites for beta-adrenergic receptor kinase-mediated phosphorylation and desensitization of the alpha 2A-adrenergic receptor.
Eason MG; Moreira SP; Liggett SB
J Biol Chem; 1995 Mar; 270(9):4681-8. PubMed ID: 7876239
[TBL] [Abstract][Full Text] [Related]
9. Mechanisms regulating the cell surface residence time of the alpha 2A-adrenergic receptor.
Wilson MH; Limbird LE
Biochemistry; 2000 Feb; 39(4):693-700. PubMed ID: 10651634
[TBL] [Abstract][Full Text] [Related]
10. Polymorphic deletion of three intracellular acidic residues of the alpha 2B-adrenergic receptor decreases G protein-coupled receptor kinase-mediated phosphorylation and desensitization.
Small KM; Brown KM; Forbes SL; Liggett SB
J Biol Chem; 2001 Feb; 276(7):4917-22. PubMed ID: 11056163
[TBL] [Abstract][Full Text] [Related]
11. Agonist-mediated downregulation of G alpha i via the alpha 2-adrenergic receptor is targeted by receptor-Gi interaction and is independent of receptor signaling and regulation.
Jewell-Motz EA; Donnelly ET; Eason MG; Liggett SB
Biochemistry; 1998 Nov; 37(45):15720-5. PubMed ID: 9843377
[TBL] [Abstract][Full Text] [Related]
12. Partial agonist clonidine mediates alpha(2)-AR subtypes specific regulation of cAMP accumulation in adenylyl cyclase II transfected DDT1-MF2 cells.
Limon-Boulez I; Bouet-Alard R; Gettys TW; Lanier SM; Maltier JP; Legrand C
Mol Pharmacol; 2001 Feb; 59(2):331-8. PubMed ID: 11160870
[TBL] [Abstract][Full Text] [Related]
13. Enhanced stability of wild-type and constitutively active alpha(2A)-adrenoceptors by ligands with agonist, silent and inverse agonist properties.
Pauwels PJ; Tardif S
Naunyn Schmiedebergs Arch Pharmacol; 2002 Aug; 366(2):134-41. PubMed ID: 12122500
[TBL] [Abstract][Full Text] [Related]
14. G(i) activator region of alpha(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation.
Wade SM; Lim WK; Lan KL; Chung DA; Nanamori M; Neubig RR
Mol Pharmacol; 1999 Nov; 56(5):1005-13. PubMed ID: 10531407
[TBL] [Abstract][Full Text] [Related]
15. Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2.
Eason MG; Liggett SB
J Biol Chem; 1992 Dec; 267(35):25473-9. PubMed ID: 1334095
[TBL] [Abstract][Full Text] [Related]
16. Chimeric mutagenesis of putative G-protein coupling domains of the alpha2A-adrenergic receptor. Localization of two redundant and fully competent gi coupling domains.
Eason MG; Liggett SB
J Biol Chem; 1996 May; 271(22):12826-32. PubMed ID: 8662784
[TBL] [Abstract][Full Text] [Related]
17. alpha 2A/alpha 2C-adrenergic receptor third loop chimera show that agonist interaction with receptor subtype backbone establishes G protein-coupled receptor kinase phosphorylation.
Jewell-Motz EA; Small KM; Theiss CT; Liggett SB
J Biol Chem; 2000 Sep; 275(37):28989-93. PubMed ID: 10893245
[TBL] [Abstract][Full Text] [Related]
18. The palmitoylated cysteine of the cytoplasmic tail of alpha 2A-adrenergic receptors confers subtype-specific agonist-promoted downregulation.
Eason MG; Jacinto MT; Theiss CT; Liggett SB
Proc Natl Acad Sci U S A; 1994 Nov; 91(23):11178-82. PubMed ID: 7972030
[TBL] [Abstract][Full Text] [Related]
19. Differential coupling of beta3A- and beta3B-adrenergic receptors to endogenous and chimeric Galphas and Galphai.
Lenard NR; Prpic V; Adamson AW; Rogers RC; Gettys TW
Am J Physiol Endocrinol Metab; 2006 Oct; 291(4):E704-15. PubMed ID: 16705062
[TBL] [Abstract][Full Text] [Related]
20. Reciprocal mutations of highly conserved residues in transmembrane helices 2 and 7 of the alpha(2A)-adrenoceptor restore agonist activation of G(i1)alpha.
Ward RJ; Milligan G
Cell Signal; 2002 Feb; 14(2):139-44. PubMed ID: 11781138
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
