BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 10954593)

  • 1. Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.
    Shen JC; Loeb LA
    Nucleic Acids Res; 2000 Sep; 28(17):3260-8. PubMed ID: 10954593
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domains.
    Machwe A; Xiao L; Orren DK
    BMC Mol Biol; 2006 Feb; 7():6. PubMed ID: 16503984
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA secondary structure of the released strand stimulates WRN helicase action on forked duplexes without coordinate action of WRN exonuclease.
    Ahn B; Bohr VA
    Biochem Biophys Res Commun; 2011 Aug; 411(4):684-9. PubMed ID: 21763283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein.
    Choudhary S; Sommers JA; Brosh RM
    J Biol Chem; 2004 Aug; 279(33):34603-13. PubMed ID: 15187093
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
    Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
    J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.
    Shen JC; Gray MD; Oshima J; Kamath-Loeb AS; Fry M; Loeb LA
    J Biol Chem; 1998 Dec; 273(51):34139-44. PubMed ID: 9852073
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Werner syndrome helicase/exonuclease (WRN) disrupts and degrades D-loops in vitro.
    Orren DK; Theodore S; Machwe A
    Biochemistry; 2002 Nov; 41(46):13483-8. PubMed ID: 12427008
    [TBL] [Abstract][Full Text] [Related]  

  • 8. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enzymatic mechanism of the WRN helicase/nuclease.
    Brosh RM; Opresko PL; Bohr VA
    Methods Enzymol; 2006; 409():52-85. PubMed ID: 16793395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence.
    Kamath-Loeb AS; Loeb LA; Johansson E; Burgers PM; Fry M
    J Biol Chem; 2001 May; 276(19):16439-46. PubMed ID: 11279038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
    von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA
    Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
    Friedemann J; Grosse F; Zhang S
    J Biol Chem; 2005 Sep; 280(35):31303-13. PubMed ID: 15995249
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.
    Li B; Comai L
    J Biol Chem; 2001 Mar; 276(13):9896-902. PubMed ID: 11152456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNase I footprinting and enhanced exonuclease function of the bipartite Werner syndrome protein (WRN) bound to partially melted duplex DNA.
    Machwe A; Xiao L; Theodore S; Orren DK
    J Biol Chem; 2002 Feb; 277(6):4492-504. PubMed ID: 11717307
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unwinding the molecular basis of the Werner syndrome.
    Shen J; Loeb LA
    Mech Ageing Dev; 2001 Jul; 122(9):921-44. PubMed ID: 11348659
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.
    Shen JC; Loeb LA
    Trends Genet; 2000 May; 16(5):213-20. PubMed ID: 10782115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.
    Kamath-Loeb AS; Welcsh P; Waite M; Adman ET; Loeb LA
    J Biol Chem; 2004 Dec; 279(53):55499-505. PubMed ID: 15489508
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease.
    Kamath-Loeb AS; Shen JC; Loeb LA; Fry M
    J Biol Chem; 1998 Dec; 273(51):34145-50. PubMed ID: 9852074
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Werner syndrome helicase contains a 5'-->3' exonuclease activity that digests DNA and RNA strands in DNA/DNA and RNA/DNA duplexes dependent on unwinding.
    Suzuki N; Shiratori M; Goto M; Furuichi Y
    Nucleic Acids Res; 1999 Jun; 27(11):2361-8. PubMed ID: 10325426
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.