BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 10956217)

  • 1. Synthesis and biological evaluation of 2'-carbamate-linked and 2'-carbonate-linked prodrugs of paclitaxel: selective activation by the tumor-associated protease plasmin.
    de Groot FM; van Berkom LW; Scheeren HW
    J Med Chem; 2000 Aug; 43(16):3093-102. PubMed ID: 10956217
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Elongated multiple electronic cascade and cyclization spacer systems in activatible anticancer prodrugs for enhanced drug release.
    de Groot FM; Loos WJ; Koekkoek R; van Berkom LW; Busscher GF; Seelen AE; Albrecht C; de Bruijn P; Scheeren HW
    J Org Chem; 2001 Dec; 66(26):8815-30. PubMed ID: 11749612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New Taxol (paclitaxel) prodrugs designed for ADEPT and PMT strategies in cancer chemotherapy.
    Alaoui AE; Saha N; Schmidt F; Monneret C; Florent JC
    Bioorg Med Chem; 2006 Jul; 14(14):5012-9. PubMed ID: 16554162
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of novel prodrugs of anthracyclines for selective activation by the tumor-associated protease plasmin.
    de Groot FM; de Bart AC; Verheijen JH; Scheeren HW
    J Med Chem; 1999 Dec; 42(25):5277-83. PubMed ID: 10602713
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heparin-paclitaxel conjugates as drug delivery system: synthesis, self-assembly property, drug release, and antitumor activity.
    Wang Y; Xin D; Liu K; Zhu M; Xiang J
    Bioconjug Chem; 2009 Dec; 20(12):2214-21. PubMed ID: 19950889
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of taxoids 5. Synthesis and evaluation of novel water-soluble prodrugs of a 3'-desphenyl-3'-cyclopropyl analogue of docetaxel.
    Yamaguchi T; Harada N; Ozaki K; Arakawa H; Oda K; Nakanishi N; Tsujihara K; Hashiyama T
    Bioorg Med Chem Lett; 1999 Jun; 9(12):1639-44. PubMed ID: 10397492
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and evaluation of water-soluble paclitaxel prodrugs.
    Feng X; Yuan YJ; Wu JC
    Bioorg Med Chem Lett; 2002 Nov; 12(22):3301-3. PubMed ID: 12392737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological activity of beta-glucuronyl carbamate-based prodrugs of paclitaxel as potential candidates for ADEPT.
    de Bont DB; Leenders RG; Haisma HJ; van der Meulen-Muileman I; Scheeren HW
    Bioorg Med Chem; 1997 Feb; 5(2):405-14. PubMed ID: 9061205
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Paclitaxel derivatives for targeted therapy of cancer: toward the development of smart taxanes.
    Safavy A; Raisch KP; Khazaeli MB; Buchsbaum DJ; Bonner JA
    J Med Chem; 1999 Nov; 42(23):4919-24. PubMed ID: 10579854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel 20-carbonate linked prodrugs of camptothecin and 9-aminocamptothecin designed for activation by tumour-associated plasmin.
    de Groot FM; Busscher GF; Aben RW; Scheeren HW
    Bioorg Med Chem Lett; 2002 Sep; 12(17):2371-6. PubMed ID: 12161136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of a dual tumor-specific motive containing integrin-targeted plasmin-cleavable doxorubicin prodrug.
    de Groot FM; Broxterman HJ; Adams HP; van Vliet A; Tesser GI; Elderkamp YW; Schraa AJ; Kok RJ; Molema G; Pinedo HM; Scheeren HW
    Mol Cancer Ther; 2002 Sep; 1(11):901-11. PubMed ID: 12481411
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulating paclitaxel bioavailability for targeting prostate cancer.
    Kumar SK; Williams SA; Isaacs JT; Denmeade SR; Khan SR
    Bioorg Med Chem; 2007 Jul; 15(14):4973-84. PubMed ID: 17502149
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A new prodrug of paclitaxel: synthesis of Protaxel.
    Seligson AL; Terry RC; Bressi JC; Douglass JG; Sovak M
    Anticancer Drugs; 2001 Apr; 12(4):305-13. PubMed ID: 11335786
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prodrugs of 4'-demethyl-4-deoxypodophyllotoxin: synthesis and evaluation of the antitumor activity.
    Kim Y; You YJ; Nam NH; Ahn BZ
    Bioorg Med Chem Lett; 2002 Dec; 12(23):3435-8. PubMed ID: 12419378
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of paclitaxel and vorinostat co-prodrugs for overcoming drug resistance in cancer therapy in vitro.
    Liu S; Zhang K; Zhu Q; Shen Q; Zhang Q; Yu J; Chen Y; Lu W
    Bioorg Med Chem; 2019 Apr; 27(7):1405-1413. PubMed ID: 30819618
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plasmin-activated prodrugs for cancer chemotherapy. 1. Synthesis and biological activity of peptidylacivicin and peptidylphenylenediamine mustard.
    Chakravarty PK; Carl PL; Weber MJ; Katzenellenbogen JA
    J Med Chem; 1983 May; 26(5):633-8. PubMed ID: 6221099
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
    Rango E; D'Antona L; Iovenitti G; Brai A; Mancini A; Zamperini C; Trivisani CI; Marianelli S; Fallacara AL; Molinari A; Cianciusi A; Schenone S; Perrotti N; Dreassi E; Botta M
    Eur J Med Chem; 2021 Nov; 223():113653. PubMed ID: 34161866
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluations of a monomethylauristatin E glucuronide prodrug for selective cancer chemotherapy.
    Legigan T; Clarhaut J; Renoux B; Tranoy-Opalinski I; Monvoisin A; Jayle C; Alsarraf J; Thomas M; Papot S
    Eur J Med Chem; 2013 Sep; 67():75-80. PubMed ID: 23845743
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and preclinical characterization of a paclitaxel prodrug with improved antitumor activity and water solubility.
    Niethammer A; Gaedicke G; Lode HN; Wrasidlo W
    Bioconjug Chem; 2001; 12(3):414-20. PubMed ID: 11353540
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and antitumor activity of novel C-7 paclitaxel ethers: discovery of BMS-184476.
    Altstadt TJ; Fairchild CR; Golik J; Johnston KA; Kadow JF; Lee FY; Long BH; Rose WC; Vyas DM; Wong H; Wu MJ; Wittman MD
    J Med Chem; 2001 Dec; 44(26):4577-83. PubMed ID: 11741476
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.