246 related articles for article (PubMed ID: 10961859)
1. Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.
Williams DA; Tao W; Yang F; Kim C; Gu Y; Mansfield P; Levine JE; Petryniak B; Derrow CW; Harris C; Jia B; Zheng Y; Ambruso DR; Lowe JB; Atkinson SJ; Dinauer MC; Boxer L
Blood; 2000 Sep; 96(5):1646-54. PubMed ID: 10961859
[TBL] [Abstract][Full Text] [Related]
2. Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency.
Gu Y; Jia B; Yang FC; D'Souza M; Harris CE; Derrow CW; Zheng Y; Williams DA
J Biol Chem; 2001 May; 276(19):15929-38. PubMed ID: 11278678
[TBL] [Abstract][Full Text] [Related]
3. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.
Debreceni B; Gao Y; Guo F; Zhu K; Jia B; Zheng Y
J Biol Chem; 2004 Jan; 279(5):3777-86. PubMed ID: 14597635
[TBL] [Abstract][Full Text] [Related]
4. Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.
Yamauchi A; Marchal CC; Molitoris J; Pech N; Knaus U; Towe J; Atkinson SJ; Dinauer MC
J Biol Chem; 2005 Jan; 280(2):953-64. PubMed ID: 15504745
[TBL] [Abstract][Full Text] [Related]
5. Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions.
Li S; Yamauchi A; Marchal CC; Molitoris JK; Quilliam LA; Dinauer MC
J Immunol; 2002 Nov; 169(9):5043-51. PubMed ID: 12391220
[TBL] [Abstract][Full Text] [Related]
6. Hematopoietic cell regulation by Rac1 and Rac2 guanosine triphosphatases.
Gu Y; Filippi MD; Cancelas JA; Siefring JE; Williams EP; Jasti AC; Harris CE; Lee AW; Prabhakar R; Atkinson SJ; Kwiatkowski DJ; Williams DA
Science; 2003 Oct; 302(5644):445-9. PubMed ID: 14564009
[TBL] [Abstract][Full Text] [Related]
7. Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.
Filippi MD; Harris CE; Meller J; Gu Y; Zheng Y; Williams DA
Nat Immunol; 2004 Jul; 5(7):744-51. PubMed ID: 15170212
[TBL] [Abstract][Full Text] [Related]
8. RAC2 GTPase deficiency and myeloid cell dysfunction in human and mouse.
Gu Y; Williams DA
J Pediatr Hematol Oncol; 2002 Dec; 24(9):791-4. PubMed ID: 12468931
[TBL] [Abstract][Full Text] [Related]
9. Cloning and characterization of bovine low molecular weight GTPases (Rac1 and Rac2) and rho GDP-dissociation inhibitor 2 (D4-GDI).
Davis AR; Clements MK; Bunger PL; Siemsen DW; Quinn MT
Vet Immunol Immunopathol; 2000 May; 74(3-4):285-301. PubMed ID: 10802295
[TBL] [Abstract][Full Text] [Related]
10. Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles.
Yamauchi A; Kim C; Li S; Marchal CC; Towe J; Atkinson SJ; Dinauer MC
J Immunol; 2004 Nov; 173(10):5971-9. PubMed ID: 15528331
[TBL] [Abstract][Full Text] [Related]
11. Rac2, a hematopoiesis-specific Rho GTPase, specifically regulates mast cell protease gene expression in bone marrow-derived mast cells.
Gu Y; Byrne MC; Paranavitana NC; Aronow B; Siefring JE; D'Souza M; Horton HF; Quilliam LA; Williams DA
Mol Cell Biol; 2002 Nov; 22(21):7645-57. PubMed ID: 12370311
[TBL] [Abstract][Full Text] [Related]
12. Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages.
Abell AN; DeCathelineau AM; Weed SA; Ambruso DR; Riches DW; Johnson GL
J Cell Sci; 2004 Jan; 117(Pt 2):243-55. PubMed ID: 14676277
[TBL] [Abstract][Full Text] [Related]
13. Clinical and functional spectrum of RAC2-related immunodeficiency.
Donkó Á; Sharapova SO; Kabat J; Ganesan S; Hauck FH; Bergerson JRE; Marois L; Abbott J; Moshous D; Williams KW; Campbell N; Martin PL; Lagresle-Peyrou C; Trojan T; Kuzmenko NB; Deordieva EA; Raykina EV; Abers MS; Abolhassani H; Barlogis V; Milla C; Hall G; Mousallem T; Church J; Kapoor N; Cros G; Chapdelaine H; Franco-Jarava C; Lopez-Lerma I; Miano M; Leiding JW; Klein C; Stasia MJ; Fischer A; Hsiao KC; Martelius T; Sepännen MRJ; Barmettler S; Walter J; Masmas TN; Mukhina AA; Falcone EL; Kracker S; Shcherbina A; Holland SM; Leto TL; Hsu AP
Blood; 2024 Apr; 143(15):1476-1487. PubMed ID: 38194689
[TBL] [Abstract][Full Text] [Related]
14. The TRQQKRP motif located near the C-terminus of Rac2 is essential for Rac2 biologic functions and intracellular localization.
Tao W; Filippi MD; Bailey JR; Atkinson SJ; Connors B; Evan A; Williams DA
Blood; 2002 Sep; 100(5):1679-88. PubMed ID: 12176888
[TBL] [Abstract][Full Text] [Related]
15. Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation.
Ambruso DR; Knall C; Abell AN; Panepinto J; Kurkchubasche A; Thurman G; Gonzalez-Aller C; Hiester A; deBoer M; Harbeck RJ; Oyer R; Johnson GL; Roos D
Proc Natl Acad Sci U S A; 2000 Apr; 97(9):4654-9. PubMed ID: 10758162
[TBL] [Abstract][Full Text] [Related]
16. Rac2 Functions in Both Neutrophils and Macrophages To Mediate Motility and Host Defense in Larval Zebrafish.
Rosowski EE; Deng Q; Keller NP; Huttenlocher A
J Immunol; 2016 Dec; 197(12):4780-4790. PubMed ID: 27837107
[TBL] [Abstract][Full Text] [Related]
17. DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.
Mavrakis KJ; McKinlay KJ; Jones P; Sablitzky F
Exp Cell Res; 2004 Apr; 294(2):335-44. PubMed ID: 15023524
[TBL] [Abstract][Full Text] [Related]
18. The role of Rac1 and Rac2 in bacterial killing.
Koh AL; Sun CX; Zhu F; Glogauer M
Cell Immunol; 2005 Jun; 235(2):92-7. PubMed ID: 16157315
[TBL] [Abstract][Full Text] [Related]
19. Rac1 and Rac2 GTPases in haematopoiesis.
Weston VJ; Stankovic T
Bioessays; 2004 Mar; 26(3):221-4. PubMed ID: 14988923
[TBL] [Abstract][Full Text] [Related]
20. Specific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophages.
Kuncewicz T; Balakrishnan P; Snuggs MB; Kone BC
Am J Physiol Renal Physiol; 2001 Aug; 281(2):F326-36. PubMed ID: 11457725
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
