BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 10966076)

  • 1. Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668. I. Taxonomy, fermentation, and biological activities.
    Omura S; Arai N; Yamaguchi Y; Masuma R; Iwai Y; Namikoshi M; Turberg A; Kölbl H; Shiomi K
    J Antibiot (Tokyo); 2000 Jun; 53(6):603-8. PubMed ID: 10966076
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Argadin, a new chitinase inhibitor, produced by Clonostachys sp. FO-7314.
    Arai N; Shiomi K; Yamaguchi Y; Masuma R; Iwai Y; Turberg A; Kölbl H; Omura S
    Chem Pharm Bull (Tokyo); 2000 Oct; 48(10):1442-6. PubMed ID: 11045447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668. II. Isolation, physico-chemical properties, and structure elucidation.
    Arai N; Shiomi K; Iwai Y; Omura S
    J Antibiot (Tokyo); 2000 Jun; 53(6):609-14. PubMed ID: 10966077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computer-aided rational molecular design of argifin-derivatives with increased inhibitory activity against chitinase B from Serratia marcescens.
    Gouda H; Sunazuka T; Iguchi K; Sugawara A; Hirose T; Noguchi Y; Saito Y; Yanai Y; Yamamoto T; Watanabe T; Shiomi K; Omura S; Hirono S
    Bioorg Med Chem Lett; 2009 May; 19(10):2630-3. PubMed ID: 19395258
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Roselipins, inhibitors of diacylglycerol acyltransferase, produced by Gliocladium roseum KF-1040.
    Tomoda H; Ohyama Y; Abe T; Tabata N; Namikoshi M; Yamaguchi Y; Masuma R; Omura S
    J Antibiot (Tokyo); 1999 Aug; 52(8):689-94. PubMed ID: 10580381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms.
    Hirose T; Sunazuka T; Omura S
    Proc Jpn Acad Ser B Phys Biol Sci; 2010; 86(2):85-102. PubMed ID: 20154467
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Natural product-guided discovery of a fungal chitinase inhibitor.
    Rush CL; Schüttelkopf AW; Hurtado-Guerrero R; Blair DE; Ibrahim AF; Desvergnes S; Eggleston IM; van Aalten DM
    Chem Biol; 2010 Dec; 17(12):1275-81. PubMed ID: 21168763
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chitinase inhibitors: extraction of the active framework from natural argifin and use of in situ click chemistry.
    Hirose T; Sunazuka T; Sugawara A; Endo A; Iguchi K; Yamamoto T; Ui H; Shiomi K; Watanabe T; Sharpless KB; Omura S
    J Antibiot (Tokyo); 2009 May; 62(5):277-82. PubMed ID: 19329983
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase.
    Sugawara A; Maita N; Gouda H; Yamamoto T; Hirose T; Kimura S; Saito Y; Nakano H; Kasai T; Nakano H; Shiomi K; Hirono S; Watanabe T; Taniguchi H; Omura S; Sunazuka T
    J Med Chem; 2015 Jun; 58(12):4984-97. PubMed ID: 26030312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SPPS of the natural product chitinase inhibitor argifin: library generation and biological evaluation.
    Dixon MJ; Andersen OA; van Aalten DM; Eggleston IM
    Adv Exp Med Biol; 2009; 611():143-4. PubMed ID: 19400131
    [No Abstract]   [Full Text] [Related]  

  • 11. Molecular modeling of human acidic mammalian chitinase in complex with the natural-product cyclopentapeptide chitinase inhibitor argifin.
    Gouda H; Terashima S; Iguchi K; Sugawara A; Saito Y; Yamamoto T; Hirose T; Shiomi K; Sunazuka T; Omura S; Hirono S
    Bioorg Med Chem; 2009 Sep; 17(17):6270-8. PubMed ID: 19666229
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.
    Rao FV; Houston DR; Boot RG; Aerts JM; Hodkinson M; Adams DJ; Shiomi K; Omura S; van Aalten DM
    Chem Biol; 2005 Jan; 12(1):65-76. PubMed ID: 15664516
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NMR spectroscopy and computational analysis of interaction between Serratia marcescens chitinase B and a dipeptide derived from natural-product cyclopentapeptide chitinase inhibitor argifin.
    Gouda H; Sunazuka T; Hirose T; Iguchi K; Yamaotsu N; Sugawara A; Noguchi Y; Saito Y; Yamamoto T; Watanabe T; Shiomi K; Omura S; Hirono S
    Bioorg Med Chem; 2010 Aug; 18(16):5835-44. PubMed ID: 20667742
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A potent insect chitinase inhibitor of fungal origin.
    Nitoda T; Usuki H; Kanzaki H
    Z Naturforsch C J Biosci; 2003; 58(11-12):891-4. PubMed ID: 14713171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel chitinase inhibitor from a marine bacterium, Pseudomonas sp.
    Izumida H; Imamura N; Sano H
    J Antibiot (Tokyo); 1996 Jan; 49(1):76-80. PubMed ID: 8609091
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TMC-95A, B, C, and D, novel proteasome inhibitors produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, production, isolation, and biological activities.
    Koguchi Y; Kohno J; Nishio M; Takahashi K; Okuda T; Ohnuki T; Komatsubara S
    J Antibiot (Tokyo); 2000 Feb; 53(2):105-9. PubMed ID: 10805568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An efficient synthesis of argifin: a natural product chitinase inhibitor with chemotherapeutic potential.
    Dixon MJ; Andersen OA; van Aalten DM; Eggleston IM
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4717-21. PubMed ID: 16153835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.
    Andersen OA; Nathubhai A; Dixon MJ; Eggleston IM; van Aalten DM
    Chem Biol; 2008 Mar; 15(3):295-301. PubMed ID: 18355729
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969.
    Tomoda H; Yamaguchi Y; Tabata N; Kobayashi T; Masuma R; Tanaka H; Omura S
    J Antibiot (Tokyo); 1996 Sep; 49(9):929-31. PubMed ID: 8931727
    [No Abstract]   [Full Text] [Related]  

  • 20. Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold.
    Dixon MJ; Nathubhai A; Andersen OA; van Aalten DM; Eggleston IM
    Org Biomol Chem; 2009 Jan; 7(2):259-68. PubMed ID: 19109670
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.