BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 10969088)

  • 1. Kinetic characterization of glutathione reductase from the malarial parasite Plasmodium falciparum. Comparison with the human enzyme.
    Bohme CC; Arscott LD; Becker K; Schirmer RH; Williams CH
    J Biol Chem; 2000 Dec; 275(48):37317-23. PubMed ID: 10969088
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion of the parasite-specific insertions and mutation of the catalytic triad in glutathione reductase from chloroquine-sensitive Plasmodium falciparum 3D7.
    Gilberger TW; Schirmer RH; Walter RD; Müller S
    Mol Biochem Parasitol; 2000 Apr; 107(2):169-79. PubMed ID: 10779594
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development.
    Sarma GN; Savvides SN; Becker K; Schirmer M; Schirmer RH; Karplus PA
    J Mol Biol; 2003 May; 328(4):893-907. PubMed ID: 12729762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Double-drug development against antioxidant enzymes from Plasmodium falciparum.
    Biot C; Dessolin J; Grellier P; Davioud-Charvet E
    Redox Rep; 2003; 8(5):280-3. PubMed ID: 14962365
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria.
    Krauth-Siegel RL; Müller JG; Lottspeich F; Schirmer RH
    Eur J Biochem; 1996 Jan; 235(1-2):345-50. PubMed ID: 8631352
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Plasmodium falciparum glutathione reductase exhibits sequence similarities with the human host enzyme in the core structure but differs at the ligand-binding sites.
    Müller S; Becker K; Bergmann B; Schirmer RH; Walter RD
    Mol Biochem Parasitol; 1995 Oct; 74(1):11-8. PubMed ID: 8719241
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline.
    Davioud-Charvet E; Delarue S; Biot C; Schwöbel B; Boehme CC; Müssigbrodt A; Maes L; Sergheraert C; Grellier P; Schirmer RH; Becker K
    J Med Chem; 2001 Nov; 44(24):4268-76. PubMed ID: 11708927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from Plasmodium falciparum.
    Färber PM; Becker K; Müller S; Schirmer RH; Franklin RM
    Eur J Biochem; 1996 Aug; 239(3):655-61. PubMed ID: 8774709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.
    Haynes RK; Chan WC; Wong HN; Li KY; Wu WK; Fan KM; Sung HH; Williams ID; Prosperi D; Melato S; Coghi P; Monti D
    ChemMedChem; 2010 Aug; 5(8):1282-99. PubMed ID: 20629071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development of a functional assay to detect inhibitors of Plasmodium falciparum glutathione reductase utilizing liquid chromatography-mass spectrometry.
    Burkard L; Scheuermann A; Simithy J; Calderón AI
    Biomed Chromatogr; 2016 Apr; 30(4):543-7. PubMed ID: 26257195
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reductive and oxidative half-reactions of glutathione reductase from Escherichia coli.
    Rietveld P; Arscott LD; Berry A; Scrutton NS; Deonarain MP; Perham RN; Williams CH
    Biochemistry; 1994 Nov; 33(46):13888-95. PubMed ID: 7947797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on
    Marozienė A; Lesanavičius M; Davioud-Charvet E; Aliverti A; Grellier P; Šarlauskas J; Čėnas N
    Molecules; 2019 Dec; 24(24):. PubMed ID: 31835450
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the intersubunit cavity of Plasmodium falciparum glutathione reductase by a novel natural inhibitor: computational and experimental evidence.
    Tyagi C; Bathke J; Goyal S; Fischer M; Dahse HM; Chacko S; Becker K; Grover A
    Int J Biochem Cell Biol; 2015 Apr; 61():72-80. PubMed ID: 25660424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A biophysically based mathematical model for the catalytic mechanism of glutathione reductase.
    Pannala VR; Bazil JN; Camara AKS; Dash RK
    Free Radic Biol Med; 2013 Dec; 65():1385-1397. PubMed ID: 24120751
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiplasmodial activity of quinones: roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase.
    Grellier P; Maroziene A; Nivinskas H; Sarlauskas J; Aliverti A; Cenas N
    Arch Biochem Biophys; 2010 Feb; 494(1):32-9. PubMed ID: 19919822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The mechanism of high Mr thioredoxin reductase from Drosophila melanogaster.
    Bauer H; Massey V; Arscott LD; Schirmer RH; Ballou DP; Williams CH
    J Biol Chem; 2003 Aug; 278(35):33020-8. PubMed ID: 12816954
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanistic studies on a novel, highly potent gold-phosphole inhibitor of human glutathione reductase.
    Deponte M; Urig S; Arscott LD; Fritz-Wolf K; Réau R; Herold-Mende C; Koncarevic S; Meyer M; Davioud-Charvet E; Ballou DP; Williams CH; Becker K
    J Biol Chem; 2005 May; 280(21):20628-37. PubMed ID: 15792952
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mixed disulfide with glutathione as an intermediate in the reaction catalyzed by glutathione reductase from yeast and as a major form of the enzyme in the cell.
    Arscott LD; Veine DM; Williams CH
    Biochemistry; 2000 Apr; 39(16):4711-21. PubMed ID: 10769127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agents.
    Belorgey D; Lanfranchi DA; Davioud-Charvet E
    Curr Pharm Des; 2013; 19(14):2512-28. PubMed ID: 23116403
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Electrophiles modulate glutathione reductase activity via alkylation and upregulation of glutathione biosynthesis.
    Jobbagy S; Vitturi DA; Salvatore SR; Turell L; Pires MF; Kansanen E; Batthyany C; Lancaster JR; Freeman BA; Schopfer FJ
    Redox Biol; 2019 Feb; 21():101050. PubMed ID: 30654300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.