These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1122 related articles for article (PubMed ID: 10973989)

  • 1. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.
    Kapoor TM; Mayer TU; Coughlin ML; Mitchison TJ
    J Cell Biol; 2000 Sep; 150(5):975-88. PubMed ID: 10973989
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint.
    Chin GM; Herbst R
    Mol Cancer Ther; 2006 Oct; 5(10):2580-91. PubMed ID: 17041103
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transient exposure to the Eg5 kinesin inhibitor monastrol leads to syntelic orientation of chromosomes and aneuploidy in mouse oocytes.
    Mailhes JB; Mastromatteo C; Fuseler JW
    Mutat Res; 2004 Apr; 559(1-2):153-67. PubMed ID: 15066583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis.
    Khodjakov A; Copenagle L; Gordon MB; Compton DA; Kapoor TM
    J Cell Biol; 2003 Mar; 160(5):671-83. PubMed ID: 12604591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.
    DeBonis S; Simorre JP; Crevel I; Lebeau L; Skoufias DA; Blangy A; Ebel C; Gans P; Cross R; Hackney DD; Wade RH; Kozielski F
    Biochemistry; 2003 Jan; 42(2):338-49. PubMed ID: 12525161
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix.
    Kapoor TM; Mitchison TJ
    J Cell Biol; 2001 Sep; 154(6):1125-33. PubMed ID: 11564753
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5.
    Maliga Z; Kapoor TM; Mitchison TJ
    Chem Biol; 2002 Sep; 9(9):989-96. PubMed ID: 12323373
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Monastrol inhibition of the mitotic kinesin Eg5.
    Cochran JC; Gatial JE; Kapoor TM; Gilbert SP
    J Biol Chem; 2005 Apr; 280(13):12658-67. PubMed ID: 15665380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes.
    O'Connell CB; Loncarek J; Hergert P; Kourtidis A; Conklin DS; Khodjakov A
    J Cell Biol; 2008 Oct; 183(1):29-36. PubMed ID: 18824563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of mitotic motors, dynein and kinesin, in the induction of abnormal centrosome integrity and multipolar spindles in cultured V79 cells exposed to dimethylarsinic acid.
    Ochi T
    Mutat Res; 2002 Jan; 499(1):73-84. PubMed ID: 11804606
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
    Mayer TU; Kapoor TM; Haggarty SJ; King RW; Schreiber SL; Mitchison TJ
    Science; 1999 Oct; 286(5441):971-4. PubMed ID: 10542155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of chromosomes in assembly of meiotic and mitotic spindles.
    Tournebize R; Heald R; Hyman A
    Prog Cell Cycle Res; 1997; 3():271-84. PubMed ID: 9552422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A role for metaphase spindle elongation forces in correction of merotelic kinetochore attachments.
    Choi SH; McCollum D
    Curr Biol; 2012 Feb; 22(3):225-30. PubMed ID: 22264609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.
    Walczak CE; Vernos I; Mitchison TJ; Karsenti E; Heald R
    Curr Biol; 1998 Jul 30-Aug 13; 8(16):903-13. PubMed ID: 9707401
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mitotic slippage and expression of survivin are linked to differential sensitivity of human cancer cell-lines to the Kinesin-5 inhibitor monastrol.
    Asraf H; Avunie-Masala R; Hershfinkel M; Gheber L
    PLoS One; 2015; 10(6):e0129255. PubMed ID: 26035434
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of the mitotic kinesin Eg5 inhibitor monastrol with P-glycoprotein.
    Peters T; Lindenmaier H; Haefeli WE; Weiss J
    Naunyn Schmiedebergs Arch Pharmacol; 2006 Jan; 372(4):291-9. PubMed ID: 16365780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of polo-like kinase 1 in the assembly of functional mitotic spindles.
    Sumara I; Giménez-Abián JF; Gerlich D; Hirota T; Kraft C; de la Torre C; Ellenberg J; Peters JM
    Curr Biol; 2004 Oct; 14(19):1712-22. PubMed ID: 15458642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles.
    Miyamoto DT; Perlman ZE; Burbank KS; Groen AC; Mitchison TJ
    J Cell Biol; 2004 Dec; 167(5):813-8. PubMed ID: 15583027
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells.
    Howell BJ; Hoffman DB; Fang G; Murray AW; Salmon ED
    J Cell Biol; 2000 Sep; 150(6):1233-50. PubMed ID: 10995431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The rate of bipolar spindle assembly depends on the microtubule-gliding velocity of the mitotic kinesin Eg5.
    Kwok BH; Yang JG; Kapoor TM
    Curr Biol; 2004 Oct; 14(19):1783-8. PubMed ID: 15458652
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 57.