These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

207 related articles for article (PubMed ID: 10974306)

  • 1. Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective.
    Bruno V; Ksiazek I; Battaglia G; Lukic S; Leonhardt T; Sauer D; Gasparini F; Kuhn R; Nicoletti F; Flor PJ
    Neuropharmacology; 2000 Sep; 39(12):2223-30. PubMed ID: 10974306
    [TBL] [Abstract][Full Text] [Related]  

  • 2. mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors.
    Movsesyan VA; O'Leary DM; Fan L; Bao W; Mullins PG; Knoblach SM; Faden AI
    J Pharmacol Exp Ther; 2001 Jan; 296(1):41-7. PubMed ID: 11123360
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors.
    Lea PM; Movsesyan VA; Faden AI
    Br J Pharmacol; 2005 Jun; 145(4):527-34. PubMed ID: 15821750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 receptors.
    Bruno V; Battaglia G; Kingston A; O'Neill MJ; Catania MV; Di Grezia R; Nicoletti F
    Neuropharmacology; 1999 Feb; 38(2):199-207. PubMed ID: 10218860
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.
    Battaglia G; Busceti CL; Molinaro G; Biagioni F; Storto M; Fornai F; Nicoletti F; Bruno V
    J Neurosci; 2004 Jan; 24(4):828-35. PubMed ID: 14749427
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity.
    Popoli P; Pintor A; Tebano MT; Frank C; Pepponi R; Nazzicone V; Grieco R; Pèzzola A; Reggio R; Minghetti L; De Berardinis MA; Martire A; Potenza RL; Domenici MR; Massotti M
    J Neurochem; 2004 Jun; 89(6):1479-89. PubMed ID: 15189351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.
    Vernon AC; Zbarsky V; Datla KP; Croucher MJ; Dexter DT
    J Neurochem; 2007 Nov; 103(3):1075-91. PubMed ID: 17714448
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices.
    Fazal A; Parker F; Palmer AM; Croucher MJ
    J Neurochem; 2003 Sep; 86(6):1346-58. PubMed ID: 12950444
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against acetaminophen hepatotoxicity in mice.
    Storto M; Ngomba RT; Battaglia G; Freitas I; Griffini P; Richelmi P; Nicoletti F; Vairetti M
    J Hepatol; 2003 Feb; 38(2):179-87. PubMed ID: 12547406
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SIB-1757 and SIB-1893: selective, noncompetitive antagonists of metabotropic glutamate receptor type 5.
    Varney MA; Cosford ND; Jachec C; Rao SP; Sacaan A; Lin FF; Bleicher L; Santori EM; Flor PJ; Allgeier H; Gasparini F; Kuhn R; Hess SD; Veliçelebi G; Johnson EC
    J Pharmacol Exp Ther; 1999 Jul; 290(1):170-81. PubMed ID: 10381773
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuroprotective activity of N-acetylaspartylglutamate in cultured cortical cells.
    Bruno V; Wroblewska B; Wroblewski JT; Fiore L; Nicoletti F
    Neuroscience; 1998 Aug; 85(3):751-7. PubMed ID: 9639269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors.
    Bruno V; Battaglia G; Copani A; Cespédes VM; Galindo MF; Ceña V; Sánchez-Prieto J; Gasparini F; Kuhn R; Flor PJ; Nicoletti F
    Eur J Neurosci; 2001 Apr; 13(8):1469-78. PubMed ID: 11328342
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism.
    O'Leary DM; Movsesyan V; Vicini S; Faden AI
    Br J Pharmacol; 2000 Dec; 131(7):1429-37. PubMed ID: 11090117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission.
    Battaglia G; Bruno V; Pisani A; Centonze D; Catania MV; Calabresi P; Nicoletti F
    Mol Cell Neurosci; 2001 Jun; 17(6):1071-83. PubMed ID: 11414795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death.
    D'Antoni S; Berretta A; Seminara G; Longone P; Giuffrida-Stella AM; Battaglia G; Sortino MA; Nicoletti F; Catania MV
    Neurobiol Dis; 2011 Jun; 42(3):252-64. PubMed ID: 21232601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats.
    Jesse CR; Savegnago L; Rocha JB; Nogueira CW
    Brain Res; 2008 Mar; 1198():197-203. PubMed ID: 18242586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia.
    Bao WL; Williams AJ; Faden AI; Tortella FC
    Brain Res; 2001 Dec; 922(2):173-9. PubMed ID: 11743947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents.
    Blaabjerg M; Fang L; Zimmer J; Baskys A
    Exp Neurol; 2003 Oct; 183(2):573-80. PubMed ID: 14552898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MGLuR5 activation reduces beta-amyloid-induced cell death in primary neuronal cultures and attenuates translocation of cytochrome c and apoptosis-inducing factor.
    Movsesyan VA; Stoica BA; Faden AI
    J Neurochem; 2004 Jun; 89(6):1528-36. PubMed ID: 15189356
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo.
    Meli E; Picca R; Attucci S; Cozzi A; Peruginelli F; Moroni F; Pellegrini-Giampietro DE
    Pharmacol Biochem Behav; 2002 Sep; 73(2):439-46. PubMed ID: 12117599
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.