BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

822 related articles for article (PubMed ID: 10976074)

  • 1. Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat.
    Mankodi A; Logigian E; Callahan L; McClain C; White R; Henderson D; Krym M; Thornton CA
    Science; 2000 Sep; 289(5485):1769-73. PubMed ID: 10976074
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities.
    Seznec H; Agbulut O; Sergeant N; Savouret C; Ghestem A; Tabti N; Willer JC; Ourth L; Duros C; Brisson E; Fouquet C; Butler-Browne G; Delacourte A; Junien C; Gourdon G
    Hum Mol Genet; 2001 Nov; 10(23):2717-26. PubMed ID: 11726559
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.
    Mahadevan MS; Yadava RS; Yu Q; Balijepalli S; Frenzel-McCardell CD; Bourne TD; Phillips LH
    Nat Genet; 2006 Sep; 38(9):1066-70. PubMed ID: 16878132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deconstructing myotonic dystrophy.
    Tapscott SJ
    Science; 2000 Sep; 289(5485):1701-2. PubMed ID: 11001736
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy.
    Wang GS; Kearney DL; De Biasi M; Taffet G; Cooper TA
    J Clin Invest; 2007 Oct; 117(10):2802-11. PubMed ID: 17823658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNA interference targeting CUG repeats in a mouse model of myotonic dystrophy.
    Sobczak K; Wheeler TM; Wang W; Thornton CA
    Mol Ther; 2013 Feb; 21(2):380-7. PubMed ID: 23183533
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy.
    Leger AJ; Mosquea LM; Clayton NP; Wu IH; Weeden T; Nelson CA; Phillips L; Roberts E; Piepenhagen PA; Cheng SH; Wentworth BM
    Nucleic Acid Ther; 2013 Apr; 23(2):109-17. PubMed ID: 23308382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting nuclear RNA for in vivo correction of myotonic dystrophy.
    Wheeler TM; Leger AJ; Pandey SK; MacLeod AR; Nakamori M; Cheng SH; Wentworth BM; Bennett CF; Thornton CA
    Nature; 2012 Aug; 488(7409):111-5. PubMed ID: 22859208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features.
    Dansithong W; Wolf CM; Sarkar P; Paul S; Chiang A; Holt I; Morris GE; Branco D; Sherwood MC; Comai L; Berul CI; Reddy S
    PLoS One; 2008; 3(12):e3968. PubMed ID: 19092997
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence.
    Kim DH; Langlois MA; Lee KB; Riggs AD; Puymirat J; Rossi JJ
    Nucleic Acids Res; 2005; 33(12):3866-74. PubMed ID: 16027111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).
    Gladman JT; Mandal M; Srinivasan V; Mahadevan MS
    PLoS One; 2013; 8(9):e72907. PubMed ID: 24039817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Myotonic dystrophy associated expanded CUG repeat muscleblind positive ribonuclear foci are not toxic to Drosophila.
    Houseley JM; Wang Z; Brock GJ; Soloway J; Artero R; Perez-Alonso M; O'Dell KM; Monckton DG
    Hum Mol Genet; 2005 Mar; 14(6):873-83. PubMed ID: 15703191
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The myotonic dystrophy expanded CUG repeat tract is necessary but not sufficient to disrupt C2C12 myoblast differentiation.
    Amack JD; Mahadevan MS
    Hum Mol Genet; 2001 Sep; 10(18):1879-87. PubMed ID: 11555624
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy.
    Philips AV; Timchenko LT; Cooper TA
    Science; 1998 May; 280(5364):737-41. PubMed ID: 9563950
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy.
    Mankodi A; Takahashi MP; Jiang H; Beck CL; Bowers WJ; Moxley RT; Cannon SC; Thornton CA
    Mol Cell; 2002 Jul; 10(1):35-44. PubMed ID: 12150905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tackling the pathogenesis of RNA nuclear retention in myotonic dystrophy.
    Mastroyiannopoulos NP; Shammas C; Phylactou LA
    Biol Cell; 2010 Jul; 102(9):515-23. PubMed ID: 20690904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DDX6 regulates sequestered nuclear CUG-expanded DMPK-mRNA in dystrophia myotonica type 1.
    Pettersson OJ; Aagaard L; Andrejeva D; Thomsen R; Jensen TG; Damgaard CK
    Nucleic Acids Res; 2014 Jun; 42(11):7186-200. PubMed ID: 24792155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of myogenesis in transgenic mice expressing the human DMPK 3'-UTR.
    Storbeck CJ; Drmanic S; Daniel K; Waring JD; Jirik FR; Parry DJ; Ahmed N; Sabourin LA; Ikeda JE; Korneluk RG
    Hum Mol Genet; 2004 Mar; 13(6):589-600. PubMed ID: 14734627
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systemic therapy in an RNA toxicity mouse model with an antisense oligonucleotide therapy targeting a non-CUG sequence within the DMPK 3'UTR RNA.
    Yadava RS; Yu Q; Mandal M; Rigo F; Bennett CF; Mahadevan MS
    Hum Mol Genet; 2020 Jun; 29(9):1440-1453. PubMed ID: 32242217
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hammerhead ribozyme-mediated destruction of nuclear foci in myotonic dystrophy myoblasts.
    Langlois MA; Lee NS; Rossi JJ; Puymirat J
    Mol Ther; 2003 May; 7(5 Pt 1):670-80. PubMed ID: 12718910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 42.