BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 10984496)

  • 1. Energetic and functional contribution of residues in the core binding factor beta (CBFbeta ) subunit to heterodimerization with CBFalpha.
    Tang YY; Shi J; Zhang L; Davis A; Bravo J; Warren AJ; Speck NA; Bushweller JH
    J Biol Chem; 2000 Dec; 275(50):39579-88. PubMed ID: 10984496
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutagenesis of the Runt domain defines two energetic hot spots for heterodimerization with the core binding factor beta subunit.
    Zhang L; Li Z; Yan J; Pradhan P; Corpora T; Cheney MD; Bravo J; Warren AJ; Bushweller JH; Speck NA
    J Biol Chem; 2003 Aug; 278(35):33097-104. PubMed ID: 12807883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.
    Tahirov TH; Inoue-Bungo T; Morii H; Fujikawa A; Sasaki M; Kimura K; Shiina M; Sato K; Kumasaka T; Yamamoto M; Ishii S; Ogata K
    Cell; 2001 Mar; 104(5):755-67. PubMed ID: 11257229
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Energetic contribution of residues in the Runx1 Runt domain to DNA binding.
    Li Z; Yan J; Matheny CJ; Corpora T; Bravo J; Warren AJ; Bushweller JH; Speck NA
    J Biol Chem; 2003 Aug; 278(35):33088-96. PubMed ID: 12807882
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biophysical characterization of interactions between the core binding factor alpha and beta subunits and DNA.
    Tang YY; Crute BE; Kelley JJ; Huang X; Yan J; Shi J; Hartman KL; Laue TM; Speck NA; Bushweller JH
    FEBS Lett; 2000 Mar; 470(2):167-72. PubMed ID: 10734228
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD; Stacy T; Liu PP; Speck NA
    Blood; 2001 Apr; 97(8):2248-56. PubMed ID: 11290585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CBFbeta allosterically regulates the Runx1 Runt domain via a dynamic conformational equilibrium.
    Yan J; Liu Y; Lukasik SM; Speck NA; Bushweller JH
    Nat Struct Mol Biol; 2004 Sep; 11(9):901-6. PubMed ID: 15322525
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The RUNX1 Runt domain at 1.25A resolution: a structural switch and specifically bound chloride ions modulate DNA binding.
    Bäckström S; Wolf-Watz M; Grundström C; Härd T; Grundström T; Sauer UH
    J Mol Biol; 2002 Sep; 322(2):259-72. PubMed ID: 12217689
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional mutagenesis of AML1/RUNX1 and PEBP2 beta/CBF beta define distinct, non-overlapping sites for DNA recognition and heterodimerization by the Runt domain.
    Nagata T; Werner MH
    J Mol Biol; 2001 Apr; 308(2):191-203. PubMed ID: 11327761
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure and backbone dynamics of Apo-CBFbeta in solution.
    Wolf-Watz M; Grundström T; Härd T
    Biochemistry; 2001 Sep; 40(38):11423-32. PubMed ID: 11560490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperative binding of DNA and CBFbeta to the Runt domain of the CBFalpha studied via MD simulations.
    Habtemariam B; Anisimov VM; MacKerell AD
    Nucleic Acids Res; 2005; 33(13):4212-22. PubMed ID: 16049027
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1).
    Gu TL; Goetz TL; Graves BJ; Speck NA
    Mol Cell Biol; 2000 Jan; 20(1):91-103. PubMed ID: 10594012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction of CBF alpha/AML/PEBP2 alpha transcription factors with nucleosomes containing promoter sequences requires flexibility in the translational positioning of the histone octamer and exposure of the CBF alpha site.
    Gutiérrez J; Sierra J; Medina R; Puchi M; Imschenetzky M; van Wijnen A; Lian J; Stein G; Stein J; Montecino M
    Biochemistry; 2000 Nov; 39(44):13565-74. PubMed ID: 11063594
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Core-binding factor beta interacts with Runx2 and is required for skeletal development.
    Yoshida CA; Furuichi T; Fujita T; Fukuyama R; Kanatani N; Kobayashi S; Satake M; Takada K; Komori T
    Nat Genet; 2002 Dec; 32(4):633-8. PubMed ID: 12434152
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo.
    Wang Q; Stacy T; Miller JD; Lewis AF; Gu TL; Huang X; Bushweller JH; Bories JC; Alt FW; Ryan G; Liu PP; Wynshaw-Boris A; Binder M; Marín-Padilla M; Sharpe AH; Speck NA
    Cell; 1996 Nov; 87(4):697-708. PubMed ID: 8929538
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystallization and preliminary X-ray analyses of quaternary, ternary and binary protein-DNA complexes with involvement of AML1/Runx-1/CBFalpha Runt domain, CBFbeta and the C/EBPbeta bZip region.
    Tahirov TH; Inoue-Bungo T; Sasaki M; Shiina M; Kimura K; Sato K; Kumasaka T; Yamamoto M; Kamiya N; Ogata K
    Acta Crystallogr D Biol Crystallogr; 2001 Jun; 57(Pt 6):850-3. PubMed ID: 11375505
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mutation in the S-switch region of the Runt domain alters the dynamics of an allosteric network responsible for CBFbeta regulation.
    Li Z; Lukasik SM; Liu Y; Grembecka J; Bielnicka I; Bushweller JH; Speck NA
    J Mol Biol; 2006 Dec; 364(5):1073-83. PubMed ID: 17059830
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates.
    Adya N; Stacy T; Speck NA; Liu PP
    Mol Cell Biol; 1998 Dec; 18(12):7432-43. PubMed ID: 9819429
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cbfbeta interacts with Runx2 and has a critical role in bone development.
    Kundu M; Javed A; Jeon JP; Horner A; Shum L; Eckhaus M; Muenke M; Lian JB; Yang Y; Nuckolls GH; Stein GS; Liu PP
    Nat Genet; 2002 Dec; 32(4):639-44. PubMed ID: 12434156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation.
    Kanno Y; Kanno T; Sakakura C; Bae SC; Ito Y
    Mol Cell Biol; 1998 Jul; 18(7):4252-61. PubMed ID: 9632809
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.