BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

472 related articles for article (PubMed ID: 10993727)

  • 1. Analysis of protein dimerization and ligand binding of orphan receptor HNF4alpha.
    Bogan AA; Dallas-Yang Q; Ruse MD; Maeda Y; Jiang G; Nepomuceno L; Scanlan TS; Cohen FE; Sladek FM
    J Mol Biol; 2000 Sep; 302(4):831-51. PubMed ID: 10993727
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Critical role of charged residues in helix 7 of the ligand binding domain in Hepatocyte Nuclear Factor 4alpha dimerisation and transcriptional activity.
    Eeckhoute J; Oxombre B; Formstecher P; Lefebvre P; Laine B
    Nucleic Acids Res; 2003 Nov; 31(22):6640-50. PubMed ID: 14602925
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MODY1 mutation Q268X in hepatocyte nuclear factor 4alpha allows for dimerization in solution but causes abnormal subcellular localization.
    Sladek FM; Dallas-Yang Q; Nepomuceno L
    Diabetes; 1998 Jun; 47(6):985-90. PubMed ID: 9604881
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand.
    Dhe-Paganon S; Duda K; Iwamoto M; Chi YI; Shoelson SE
    J Biol Chem; 2002 Oct; 277(41):37973-6. PubMed ID: 12193589
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of critical residues for heterodimerization within the ligand-binding domain of retinoid X receptor.
    Lee SK; Na SY; Kim HJ; Soh J; Choi HS; Lee JW
    Mol Endocrinol; 1998 Mar; 12(3):325-32. PubMed ID: 9514150
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conserved amino acids in the ligand-binding and tau(i) domains of the peroxisome proliferator-activated receptor alpha are necessary for heterodimerization with RXR.
    Gorla-Bajszczak A; Juge-Aubry C; Pernin A; Burger AG; Meier CA
    Mol Cell Endocrinol; 1999 Jan; 147(1-2):37-47. PubMed ID: 10195690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dimerization defective MODY mutations of hepatocyte nuclear factor 4α.
    Singh P; Tung SP; Han EH; Lee IK; Chi YI
    Mutat Res; 2019 Mar; 814():1-6. PubMed ID: 30648609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain.
    Ruse MD; Privalsky ML; Sladek FM
    Mol Cell Biol; 2002 Mar; 22(6):1626-38. PubMed ID: 11865043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Polyamines modulate the interaction between nuclear receptors and vitamin D receptor-interacting protein 205.
    Maeda Y; Rachez C; Hawel L; Byus CV; Freedman LP; Sladek FM
    Mol Endocrinol; 2002 Jul; 16(7):1502-10. PubMed ID: 12089346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator.
    Eeckhoute J; Formstecher P; Laine B
    Mol Endocrinol; 2001 Jul; 15(7):1200-10. PubMed ID: 11435618
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding specificity and modulation of the human ApoCIII promoter activity by heterodimers of ligand-dependent nuclear receptors.
    Lavrentiadou SN; Hadzopoulou-Cladaras M; Kardassis D; Zannis VI
    Biochemistry; 1999 Jan; 38(3):964-75. PubMed ID: 9893992
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical role of residues defining the ligand binding pocket in hepatocyte nuclear factor-4alpha.
    Aggelidou E; Iordanidou P; Tsantili P; Papadopoulos G; Hadzopoulou-Cladaras M
    J Biol Chem; 2004 Jul; 279(29):30680-8. PubMed ID: 15123688
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutations in hepatocyte nuclear factor 4alpha (HNF4alpha) gene associated with diabetes result in greater loss of HNF4alpha function in pancreatic beta-cells than in nonpancreatic beta-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells.
    Oxombre B; Moerman E; Eeckhoute J; Formstecher P; Laine B
    J Mol Med (Berl); 2002 Jul; 80(7):423-30. PubMed ID: 12110948
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The dimerization domain of HNF-1alpha: structure and plasticity of an intertwined four-helix bundle with application to diabetes mellitus.
    Narayana N; Hua Q; Weiss MA
    J Mol Biol; 2001 Jul; 310(3):635-58. PubMed ID: 11439029
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of hinge domain in heterodimerization and specific DNA recognition by nuclear receptors.
    Miyamoto T; Kakizawa T; Ichikawa K; Nishio S; Takeda T; Suzuki S; Kaneko A; Kumagai M; Mori J; Yamashita K; Sakuma T; Hashizume K
    Mol Cell Endocrinol; 2001 Jul; 181(1-2):229-38. PubMed ID: 11476956
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Developmentally regulated N-terminal variants of the nuclear receptor hepatocyte nuclear factor 4alpha mediate multiple interactions through coactivator and corepressor-histone deacetylase complexes.
    Torres-Padilla ME; Sladek FM; Weiss MC
    J Biol Chem; 2002 Nov; 277(47):44677-87. PubMed ID: 12205093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of ligand binding on the association properties and conformation in solution of retinoic acid receptors RXR and RAR.
    Egea PF; Rochel N; Birck C; Vachette P; Timmins PA; Moras D
    J Mol Biol; 2001 Mar; 307(2):557-76. PubMed ID: 11254382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The NMR solution structure of a mutant of the Max b/HLH/LZ free of DNA: insights into the specific and reversible DNA binding mechanism of dimeric transcription factors.
    Sauvé S; Tremblay L; Lavigne P
    J Mol Biol; 2004 Sep; 342(3):813-32. PubMed ID: 15342239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Manipulation of reciprocal salt bridges at the heterodimerization interface alters the dimerization properties of mouse RXRalpha and PPARgamma1.
    Chan LS; Wells RA
    Biochem Biophys Res Commun; 2007 Jul; 358(4):1080-5. PubMed ID: 17521607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ligand specificity and conformational dependence of the hepatic nuclear factor-4alpha (HNF-4alpha ).
    Petrescu AD; Hertz R; Bar-Tana J; Schroeder F; Kier AB
    J Biol Chem; 2002 Jul; 277(27):23988-99. PubMed ID: 11940586
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.