BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 10995873)

  • 1. Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin.
    Shinohara H; Fan D; Ozawa S; Yano S; Van Arsdell M; Viner JL; Beers R; Pastan I; Fidler IJ
    Int J Oncol; 2000 Oct; 17(4):643-51. PubMed ID: 10995873
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
    Batra JK; Fitzgerald DJ; Chaudhary VK; Pastan I
    Mol Cell Biol; 1991 Apr; 11(4):2200-5. PubMed ID: 2005905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study.
    Wang G; Kumar A; Ding W; Korangath P; Bera T; Wei J; Pai P; Gabrielson K; Pastan I; Sukumar S
    Proc Natl Acad Sci U S A; 2022 Jun; 119(24):e2200200119. PubMed ID: 35675429
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monovalent immunotoxin containing truncated form of Pseudomonas exotoxin as potent antitumor agent.
    Debinski W; Pastan I
    Cancer Res; 1992 Oct; 52(19):5379-85. PubMed ID: 1394141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Anti-Tac(Fab)-PE40, a recombinant double-chain immunotoxin which kills interleukin-2-receptor-bearing cells and induces complete remission in an in vivo tumor model.
    Kreitman RJ; Chang CN; Hudson DV; Queen C; Bailon P; Pastan I
    Int J Cancer; 1994 Jun; 57(6):856-64. PubMed ID: 8206679
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
    Kreitman RJ; Chaudhary VK; Waldmann T; Willingham MC; FitzGerald DJ; Pastan I
    Proc Natl Acad Sci U S A; 1990 Nov; 87(21):8291-5. PubMed ID: 2236041
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice.
    Reiter Y; Wright AF; Tonge DW; Pastan I
    Int J Cancer; 1996 Jul; 67(1):113-23. PubMed ID: 8690511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Immunotoxins made with a recombinant form of Pseudomonas exotoxin A that do not require proteolysis for activity.
    Theuer CP; Kreitman RJ; FitzGerald DJ; Pastan I
    Cancer Res; 1993 Jan; 53(2):340-7. PubMed ID: 8417828
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.
    Siegall CB; Chace D; Mixan B; Garrigues U; Wan H; Paul L; Wolff E; Hellström I; Hellström KE
    J Immunol; 1994 Mar; 152(5):2377-84. PubMed ID: 8133048
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Immunotoxins to the murine transferrin receptor: intracavitary therapy of mice bearing syngeneic peritoneal tumors.
    Bjorn MJ; Groetsema G
    Cancer Res; 1987 Dec; 47(24 Pt 1):6639-45. PubMed ID: 3499979
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recombinant immunotoxins containing anti-Tac(Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human carcinoma.
    Kreitman RJ; Bailon P; Chaudhary VK; FitzGerald DJ; Pastan I
    Blood; 1994 Jan; 83(2):426-34. PubMed ID: 8286741
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An immunotoxin composed of a monoclonal antitransferrin receptor antibody linked by a disulfide bond to the ribosome-inactivating protein gelonin: potent in vitro and in vivo effects against human tumors.
    Scott CF; Goldmacher VS; Lambert JM; Jackson JV; McIntyre GD
    J Natl Cancer Inst; 1987 Nov; 79(5):1163-72. PubMed ID: 3500356
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytotoxic and antitumor activity of a recombinant tumor necrosis factor-B1(Fv) fusion protein on LeY antigen-expressing human cancer cells.
    Scherf U; Benhar I; Webber KO; Pastan I; Brinkmann U
    Clin Cancer Res; 1996 Sep; 2(9):1523-31. PubMed ID: 9816329
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.
    Kreitman RJ; Chaudhary VK; Waldmann TA; Hanchard B; Cranston B; FitzGerald DJ; Pastan I
    Leukemia; 1993 Apr; 7(4):553-62. PubMed ID: 8464234
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recombinant antibody fragments and immunotoxin fusions for cancer therapy.
    Brinkmann U
    In Vivo; 2000; 14(1):21-7. PubMed ID: 10757057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of HER2 in human gastric cancer cells directly correlates with antitumor activity of a recombinant disulfide-stabilized anti-HER2 immunotoxin.
    Shinohara H; Morita S; Kawai M; Miyamoto A; Sonoda T; Pastan I; Tanigawa N
    J Surg Res; 2002 Feb; 102(2):169-77. PubMed ID: 11796015
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Improved cytotoxic activity toward cell lines and fresh leukemia cells of a mutant anti-CD22 immunotoxin obtained by antibody phage display.
    Salvatore G; Beers R; Margulies I; Kreitman RJ; Pastan I
    Clin Cancer Res; 2002 Apr; 8(4):995-1002. PubMed ID: 11948105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor activity of intraperitoneal immunotoxins in a nude mouse model of human malignant mesothelioma.
    Griffin TW; Richardson C; Houston LL; LePage D; Bogden A; Raso V
    Cancer Res; 1987 Aug; 47(16):4266-70. PubMed ID: 3496960
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin.
    Batra JK; Jinno Y; Chaudhary VK; Kondo T; Willingham MC; FitzGerald DJ; Pastan I
    Proc Natl Acad Sci U S A; 1989 Nov; 86(21):8545-9. PubMed ID: 2510169
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor activity of an immunotoxin in a nude mouse model of human ovarian cancer.
    FitzGerald DJ; Bjorn MJ; Ferris RJ; Winkelhake JL; Frankel AE; Hamilton TC; Ozols RF; Willingham MC; Pastan I
    Cancer Res; 1987 Mar; 47(5):1407-10. PubMed ID: 3493065
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.