BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 10996399)

  • 1. The thymidylate synthase inhibitor ZD1694 potently inhibits murine and human cytomegalovirus replication in quiescent fibroblasts.
    Lembo D; Gribaudo G; Riera L; Mondo A; Cavallo R; Angeretti A; Landolfo S
    Antiviral Res; 2000 Aug; 47(2):111-20. PubMed ID: 10996399
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The anticytomegaloviral activity of raltitrexed is abrogated in quiescent mouse fibroblasts that overexpress thymidylate synthase.
    Gribaudo G; Riera L; Lembo D; De Andrea M; Johnson LF; Landolfo S
    Virus Res; 2001 Jan; 73(1):57-65. PubMed ID: 11163644
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Murine cytomegalovirus stimulates cellular thymidylate synthase gene expression in quiescent cells and requires the enzyme for replication.
    Gribaudo G; Riera L; Lembo D; De Andrea M; Gariglio M; Rudge TL; Johnson LF; Landolfo S
    J Virol; 2000 Jun; 74(11):4979-87. PubMed ID: 10799571
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
    Herget T; Freitag M; Morbitzer M; Kupfer R; Stamminger T; Marschall M
    Antimicrob Agents Chemother; 2004 Nov; 48(11):4154-62. PubMed ID: 15504835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
    Jackman AL; Kelland LR; Kimbell R; Brown M; Gibson W; Aherne GW; Hardcastle A; Boyle FT
    Br J Cancer; 1995 May; 71(5):914-24. PubMed ID: 7537518
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro and in vivo activity of 1-O-hexadecylpropanediol-3-phospho-ganciclovir and 1-O-hexadecylpropanediol-3-phospho-penciclovir in cytomegalovirus and herpes simplex virus infections.
    Hostetler KY; Rybak RJ; Beadle JR; Gardner MF; Aldern KA; Wright KN; Kern ER
    Antivir Chem Chemother; 2001 Jan; 12(1):61-70. PubMed ID: 11437323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison between human cytomegalovirus pUL97 and murine cytomegalovirus (MCMV) pM97 expressed by MCMV and vaccinia virus: pM97 does not confer ganciclovir sensitivity.
    Wagner M; Michel D; Schaarschmidt P; Vaida B; Jonjic S; Messerle M; Mertens T; Koszinowski U
    J Virol; 2000 Nov; 74(22):10729-36. PubMed ID: 11044117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 and WAF1 are induced and Rb protein is hypophosphorylated during cell growth inhibition by the thymidylate synthase inhibitor ZD1694 (Tomudex).
    Yin MB; Voigt W; Panadero A; Vanhoefer U; Frank C; Pajovic S; Azizkhan J; Rustum YM
    Mol Pharmacol; 1997 Apr; 51(4):630-6. PubMed ID: 9106628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Cytomegalovirus Replication with Extended-Half-Life Synthetic Ozonides.
    Wang Y; Mukhopadhyay R; Roy S; Kapoor A; Su YP; Charman SA; Chen G; Wu J; Wang X; Vennerstrom JL; Arav-Boger R
    Antimicrob Agents Chemother; 2019 Jan; 63(1):. PubMed ID: 30373792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PD0084430: a non-nucleoside inhibitor of human cytomegalovirus replication in vitro.
    Meyer AL; Bruening EE; Dunkle WE; Booth RJ; Steinbaugh BA; Vara Prasad JV
    Antiviral Res; 2001 Dec; 52(3):289-300. PubMed ID: 11675146
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anticytomegalovirus Peptides Point to New Insights for CMV Entry Mechanisms and the Limitations of
    Jackson JW; Hancock TJ; Dogra P; Patel R; Arav-Boger R; Williams AD; Kennel SJ; Wall JS; Sparer TE
    mSphere; 2019 Feb; 4(1):. PubMed ID: 30760613
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
    Neyts J; De Clercq E
    Verh K Acad Geneeskd Belg; 1994; 56(6):561-92. PubMed ID: 7892749
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Human cytomegalovirus infection induces cellular thymidylate synthase gene expression in quiescent fibroblasts.
    Gribaudo G; Riera L; Rudge TL; Caposio P; Johnson LF; Landolfo S
    J Gen Virol; 2002 Dec; 83(Pt 12):2983-2993. PubMed ID: 12466474
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of resistance to N-[5-[N-(3,4-dihydro-2-methyl-4- oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ZD1694), a folate-based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line.
    Lu K; Yin MB; McGuire JJ; Bonmassar E; Rustum YM
    Biochem Pharmacol; 1995 Jul; 50(3):391-8. PubMed ID: 7646540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
    Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.
    Kaptein SJ; Efferth T; Leis M; Rechter S; Auerochs S; Kalmer M; Bruggeman CA; Vink C; Stamminger T; Marschall M
    Antiviral Res; 2006 Feb; 69(2):60-9. PubMed ID: 16325931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The folate antagonist, methotrexate, is a potent inhibitor of murine and human cytomegalovirus in vitro.
    Shanley JD; Debs RJ
    Antiviral Res; 1989 Mar; 11(2):99-106. PubMed ID: 2543289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory effects of tricin derivative from Sasa albo-marginata on replication of human cytomegalovirus.
    Akuzawa K; Yamada R; Li Z; Li Y; Sadanari H; Matsubara K; Watanabe K; Koketsu M; Tuchida Y; Murayama T
    Antiviral Res; 2011 Sep; 91(3):296-303. PubMed ID: 21745500
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (1110U81) potently inhibits human cytomegalovirus replication and potentiates the antiviral effects of ganciclovir.
    Hamzeh FM; Spector T; Lietman PS
    Antimicrob Agents Chemother; 1993 Mar; 37(3):602-4. PubMed ID: 8384821
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors.
    Hutterer C; Hamilton S; Steingruber M; Zeitträger I; Bahsi H; Thuma N; Naing Z; Örfi Z; Örfi L; Socher E; Sticht H; Rawlinson W; Chou S; Haupt VJ; Marschall M
    Antiviral Res; 2016 Oct; 134():130-143. PubMed ID: 27515131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.