BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

506 related articles for article (PubMed ID: 10997946)

  • 1. Selective inhibition of human cytochrome P450 3A4 by N-[2(R)-hydroxy-1(S)-indanyl]-5-[2(S)-(1, 1-dimethylethylaminocarbonyl)-4-[(furo[2, 3-b]pyridin-5-yl)methyl]piperazin-1-yl]-4(S)-hydroxy-2(R)-phenylmethy lpentanamide and P-glycoprotein by valspodar in gene transfectant systems.
    Kawahara I; Kato Y; Suzuki H; Achira M; Ito K; Crespi CL; Sugiyama Y
    Drug Metab Dispos; 2000 Oct; 28(10):1238-43. PubMed ID: 10997946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4.
    Achira M; Suzuki H; Ito K; Sugiyama Y
    AAPS PharmSci; 1999; 1(4):E18. PubMed ID: 11741214
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitory potencies of 1,4-dihydropyridine calcium antagonists to P-glycoprotein-mediated transport: comparison with the effects on CYP3A4.
    Katoh M; Nakajima M; Yamazaki H; Yokoi T
    Pharm Res; 2000 Oct; 17(10):1189-97. PubMed ID: 11145223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Creation of polarized cells coexpressing CYP3A4, NADPH cytochrome P450 reductase and MDR1/P-glycoprotein.
    Brimer C; Dalton JT; Zhu Z; Schuetz J; Yasuda K; Vanin E; Relling MV; Lu Y; Schuetz EG
    Pharm Res; 2000 Jul; 17(7):803-10. PubMed ID: 10990198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.
    Ohnishi A; Matsuo H; Yamada S; Takanaga H; Morimoto S; Shoyama Y; Ohtani H; Sawada Y
    Br J Pharmacol; 2000 Jul; 130(6):1369-77. PubMed ID: 10903978
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitory effects of CYP3A4 substrates and their metabolites on P-glycoprotein-mediated transport.
    Katoh M; Nakajima M; Yamazaki H; Yokoi T
    Eur J Pharm Sci; 2001 Feb; 12(4):505-13. PubMed ID: 11231118
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4.
    Bhardwaj RK; Glaeser H; Becquemont L; Klotz U; Gupta SK; Fromm MF
    J Pharmacol Exp Ther; 2002 Aug; 302(2):645-50. PubMed ID: 12130727
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
    Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
    Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of P450 CYP3A4-dependent metabolism by P-glycoprotein: implications for P450 phenotyping.
    Baron JM; Goh LB; Yao D; Wolf CR; Friedberg T
    J Pharmacol Exp Ther; 2001 Feb; 296(2):351-8. PubMed ID: 11160617
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A; Satoh H; Thomas PE; Bush E; Moore D
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4.
    Takanaga H; Ohnishi A; Yamada S; Matsuo H; Morimoto S; Shoyama Y; Ohtani H; Sawada Y
    J Pharmacol Exp Ther; 2000 Apr; 293(1):230-6. PubMed ID: 10734174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantitative distinctions of active site molecular recognition by P-glycoprotein and cytochrome P450 3A4.
    Wang E; Lew K; Barecki M; Casciano CN; Clement RP; Johnson WW
    Chem Res Toxicol; 2001 Dec; 14(12):1596-603. PubMed ID: 11743742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.
    Sakaeda T; Fujino H; Komoto C; Kakumoto M; Jin JS; Iwaki K; Nishiguchi K; Nakamura T; Okamura N; Okumura K
    Pharm Res; 2006 Mar; 23(3):506-12. PubMed ID: 16388406
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD; Hidalgo IJ; Segura-Aguilar J; Artursson P
    Pharm Res; 1999 May; 16(5):625-32. PubMed ID: 10350002
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs.
    Sakaeda T; Iwaki K; Kakumoto M; Nishikawa M; Niwa T; Jin JS; Nakamura T; Nishiguchi K; Okamura N; Okumura K
    J Pharm Pharmacol; 2005 Jun; 57(6):759-64. PubMed ID: 15969931
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J; Innocenti F; Schuetz EG; Flockhart DA; Relling MV; Santucci R; Ratain MJ
    Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro and in vivo CYP3A64 induction and inhibition studies in rhesus monkeys: a preclinical approach for CYP3A-mediated drug interaction studies.
    Prueksaritanont T; Kuo Y; Tang C; Li C; Qiu Y; Lu B; Strong-Basalyga K; Richards K; Carr B; Lin JH
    Drug Metab Dispos; 2006 Sep; 34(9):1546-55. PubMed ID: 16782766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Furanocoumarin derivatives in Kampo extract medicines inhibit cytochrome P450 3A4 and P-glycoprotein.
    Iwanaga K; Hayashi M; Hamahata Y; Miyazaki M; Shibano M; Taniguchi M; Baba K; Kakemi M
    Drug Metab Dispos; 2010 Aug; 38(8):1286-94. PubMed ID: 20463004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity.
    Patel J; Buddha B; Dey S; Pal D; Mitra AK
    Am J Ther; 2004; 11(4):262-77. PubMed ID: 15266218
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.