309 related articles for article (PubMed ID: 10998360)
1. Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components.
Fleming IN; Gray A; Downes CP
Biochem J; 2000 Oct; 351(Pt 1):173-82. PubMed ID: 10998360
[TBL] [Abstract][Full Text] [Related]
2. Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1.
Fleming IN; Batty IH; Prescott AR; Gray A; Kular GS; Stewart H; Downes CP
Biochem J; 2004 Sep; 382(Pt 3):857-65. PubMed ID: 15242348
[TBL] [Abstract][Full Text] [Related]
3. Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.
Ugolev Y; Berdichevsky Y; Weinbaum C; Pick E
J Biol Chem; 2008 Aug; 283(32):22257-71. PubMed ID: 18505730
[TBL] [Abstract][Full Text] [Related]
4. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
Michiels F; Stam JC; Hordijk PL; van der Kammen RA; Ruuls-Van Stalle L; Feltkamp CA; Collard JG
J Cell Biol; 1997 Apr; 137(2):387-98. PubMed ID: 9128250
[TBL] [Abstract][Full Text] [Related]
5. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
Boissier P; Huynh-Do U
Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
[TBL] [Abstract][Full Text] [Related]
6. Lipid products of phosphoinositide 3-kinase interact with Rac1 GTPase and stimulate GDP dissociation.
Missy K; Van Poucke V; Raynal P; Viala C; Mauco G; Plantavid M; Chap H; Payrastre B
J Biol Chem; 1998 Nov; 273(46):30279-86. PubMed ID: 9804788
[TBL] [Abstract][Full Text] [Related]
7. Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands.
Crompton AM; Foley LH; Wood A; Roscoe W; Stokoe D; McCormick F; Symons M; Bollag G
J Biol Chem; 2000 Aug; 275(33):25751-9. PubMed ID: 10835422
[TBL] [Abstract][Full Text] [Related]
8. Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid.
Buchanan FG; Elliot CM; Gibbs M; Exton JH
J Biol Chem; 2000 Mar; 275(13):9742-8. PubMed ID: 10734127
[TBL] [Abstract][Full Text] [Related]
9. Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.
Bourguignon LY; Zhu H; Shao L; Chen YW
J Cell Biol; 2000 Jul; 150(1):177-91. PubMed ID: 10893266
[TBL] [Abstract][Full Text] [Related]
10. The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.
Xu Z; Gakhar L; Bain FE; Spies M; Fuentes EJ
J Biol Chem; 2017 Oct; 292(43):17777-17793. PubMed ID: 28882897
[TBL] [Abstract][Full Text] [Related]
11. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
Servitja JM; Marinissen MJ; Sodhi A; Bustelo XR; Gutkind JS
J Biol Chem; 2003 Sep; 278(36):34339-46. PubMed ID: 12810717
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Worthylake DK; Rossman KL; Sondek J
Nature; 2000 Dec; 408(6813):682-8. PubMed ID: 11130063
[TBL] [Abstract][Full Text] [Related]
13. Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation.
Fleming IN; Elliott CM; Buchanan FG; Downes CP; Exton JH
J Biol Chem; 1999 Apr; 274(18):12753-8. PubMed ID: 10212259
[TBL] [Abstract][Full Text] [Related]
14. CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration.
Bourguignon LY; Zhu H; Shao L; Chen YW
J Biol Chem; 2000 Jan; 275(3):1829-38. PubMed ID: 10636882
[TBL] [Abstract][Full Text] [Related]
15. Pleckstrin homology domain-mediated activation of the rho-specific guanine nucleotide exchange factor Dbs by Rac1.
Cheng L; Mahon GM; Kostenko EV; Whitehead IP
J Biol Chem; 2004 Mar; 279(13):12786-93. PubMed ID: 14701795
[TBL] [Abstract][Full Text] [Related]
16. Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1.
Otsuki Y; Tanaka M; Yoshii S; Kawazoe N; Nakaya K; Sugimura H
Proc Natl Acad Sci U S A; 2001 Apr; 98(8):4385-90. PubMed ID: 11274357
[TBL] [Abstract][Full Text] [Related]
17. Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis.
Qi H; Juo P; Masuda-Robens J; Caloca MJ; Zhou H; Stone N; Kazanietz MG; Chou MM
Cell Growth Differ; 2001 Dec; 12(12):603-11. PubMed ID: 11751455
[TBL] [Abstract][Full Text] [Related]
18. Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.
Han J; Luby-Phelps K; Das B; Shu X; Xia Y; Mosteller RD; Krishna UM; Falck JR; White MA; Broek D
Science; 1998 Jan; 279(5350):558-60. PubMed ID: 9438848
[TBL] [Abstract][Full Text] [Related]
19. Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain.
Stam JC; Sander EE; Michiels F; van Leeuwen FN; Kain HE; van der Kammen RA; Collard JG
J Biol Chem; 1997 Nov; 272(45):28447-54. PubMed ID: 9353304
[TBL] [Abstract][Full Text] [Related]
20. Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2.
Joseph RE; Norris FA
J Biol Chem; 2005 Jul; 280(30):27508-12. PubMed ID: 15897194
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]