These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

82 related articles for article (PubMed ID: 10998555)

  • 1. Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations.
    Leutner S; Czech C; Schindowski K; Touchet N; Eckert A; Müller WE
    Neurosci Lett; 2000 Oct; 292(2):87-90. PubMed ID: 10998555
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aging sensitizes toward ROS formation and lipid peroxidation in PS1M146L transgenic mice.
    Schuessel K; Frey C; Jourdan C; Keil U; Weber CC; Müller-Spahn F; Müller WE; Eckert A
    Free Radic Biol Med; 2006 Mar; 40(5):850-62. PubMed ID: 16520237
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.
    Guo Q; Sebastian L; Sopher BL; Miller MW; Ware CB; Martin GM; Mattson MP
    J Neurochem; 1999 Mar; 72(3):1019-29. PubMed ID: 10037473
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Object recognition memory and cholinergic parameters in mice expressing human presenilin 1 transgenes.
    Vaucher E; Fluit P; Chishti MA; Westaway D; Mount HT; Kar S
    Exp Neurol; 2002 Jun; 175(2):398-406. PubMed ID: 12061869
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
    Qian S; Jiang P; Guan XM; Singh G; Trumbauer ME; Yu H; Chen HY; Van de Ploeg LH; Zheng H
    Neuron; 1998 Mar; 20(3):611-7. PubMed ID: 9539133
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of dietary supplementation of dates in Alzheimer's disease APPsw/2576 transgenic mice on oxidative stress and antioxidant status.
    Subash S; Essa MM; Al-Asmi A; Al-Adawi S; Vaishnav R; Guillemin GJ
    Nutr Neurosci; 2015 Aug; 18(6):281-8. PubMed ID: 24954036
    [TBL] [Abstract][Full Text] [Related]  

  • 7. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL; Slunt HH; Gonzales V; Jenkins NA; Copeland NG; Borchelt DR
    Neurobiol Aging; 2004 Aug; 25(7):885-92. PubMed ID: 15212842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Alzheimer's disease-like alterations in peripheral cells from presenilin-1 transgenic mice.
    Eckert A; Schindowski K; Leutner S; Luckhaus C; Touchet N; Czech C; Müller WE
    Neurobiol Dis; 2001 Apr; 8(2):331-42. PubMed ID: 11300728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.
    Sadowski M; Pankiewicz J; Scholtzova H; Ji Y; Quartermain D; Jensen CH; Duff K; Nixon RA; Gruen RJ; Wisniewski T
    J Neuropathol Exp Neurol; 2004 May; 63(5):418-28. PubMed ID: 15198121
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neurotrophic factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 mutation.
    Guo Q; Sebastian L; Sopher BL; Miller MW; Glazner GW; Ware CB; Martin GM; Mattson MP
    Proc Natl Acad Sci U S A; 1999 Mar; 96(7):4125-30. PubMed ID: 10097174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T; Imaizumi K; Sato N; Miyoshi K; Kudo T; Hitomi J; Morihara T; Yoneda T; Gomi F; Mori Y; Nakano Y; Takeda J; Tsuda T; Itoyama Y; Murayama O; Takashima A; St George-Hyslop P; Takeda M; Tohyama M
    Nat Cell Biol; 1999 Dec; 1(8):479-85. PubMed ID: 10587643
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F; Czech C; Esclaire F; Elyaman W; Yardin C; Baclet MC; Touchet N; Tremp G; Pradier L; Hugon J
    J Neurosci Res; 2002 Aug; 69(4):530-9. PubMed ID: 12210846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Organoselenium (Sel-Plex diet) decreases amyloid burden and RNA and DNA oxidative damage in APP/PS1 mice.
    Lovell MA; Xiong S; Lyubartseva G; Markesbery WR
    Free Radic Biol Med; 2009 Jun; 46(11):1527-33. PubMed ID: 19303433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice.
    Schuessel K; Schäfer S; Bayer TA; Czech C; Pradier L; Müller-Spahn F; Müller WE; Eckert A
    Neurobiol Dis; 2005 Feb; 18(1):89-99. PubMed ID: 15649699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway.
    Jaffar S; Counts SE; Ma SY; Dadko E; Gordon MN; Morgan D; Mufson EJ
    Exp Neurol; 2001 Aug; 170(2):227-43. PubMed ID: 11476589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1.
    Boutajangout A; Leroy K; Touchet N; Authelet M; Blanchard V; Tremp G; Pradier L; Brion JP
    Neurosci Lett; 2002 Jan; 318(1):29-33. PubMed ID: 11786218
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes.
    Arendash GW; King DL; Gordon MN; Morgan D; Hatcher JM; Hope CE; Diamond DM
    Brain Res; 2001 Feb; 891(1-2):42-53. PubMed ID: 11164808
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
    Sato N; Urano F; Yoon Leem J; Kim SH; Li M; Donoviel D; Bernstein A; Lee AS; Ron D; Veselits ML; Sisodia SS; Thinakaran G
    Nat Cell Biol; 2000 Dec; 2(12):863-70. PubMed ID: 11146649
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH; Hof PR; Chen X; Gluck K; Austin G; Younkin SG; Younkin LH; DeGasperi R; Gama Sosa MA; Robakis NK; Haroutunian V; Elder GA
    Exp Neurol; 2004 Aug; 188(2):224-37. PubMed ID: 15246822
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.