BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 10999959)

  • 1. Mdr1 limits CYP3A metabolism in vivo.
    Lan LB; Dalton JT; Schuetz EG
    Mol Pharmacol; 2000 Oct; 58(4):863-9. PubMed ID: 10999959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Kim RB; Wandel C; Leake B; Cvetkovic M; Fromm MF; Dempsey PJ; Roden MM; Belas F; Chaudhary AK; Roden DM; Wood AJ; Wilkinson GR
    Pharm Res; 1999 Mar; 16(3):408-14. PubMed ID: 10213372
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein.
    Evans DC; O'Connor D; Lake BG; Evers R; Allen C; Hargreaves R
    Drug Metab Dispos; 2003 Jul; 31(7):861-9. PubMed ID: 12814962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
    Yasuda K; Lan LB; Sanglard D; Furuya K; Schuetz JD; Schuetz EG
    J Pharmacol Exp Ther; 2002 Oct; 303(1):323-32. PubMed ID: 12235267
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers.
    Salphati L; Benet LZ
    Biochem Pharmacol; 1998 Feb; 55(4):387-95. PubMed ID: 9514072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
    Raeissi SD; Hidalgo IJ; Segura-Aguilar J; Artursson P
    Pharm Res; 1999 May; 16(5):625-32. PubMed ID: 10350002
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes.
    Schuetz EG; Umbenhauer DR; Yasuda K; Brimer C; Nguyen L; Relling MV; Schuetz JD; Schinkel AH
    Mol Pharmacol; 2000 Jan; 57(1):188-97. PubMed ID: 10617694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Early postoperative erythromycin breath test correlates with hepatic cytochrome P4503A activity in liver transplant recipients.
    Schmidt LE; Olsen AK; Stentoft K; Rasmussen A; Kirkegaard P; Dalhoff K
    Clin Pharmacol Ther; 2001 Nov; 70(5):446-54. PubMed ID: 11719731
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
    Schuetz EG; Schinkel AH; Relling MV; Schuetz JD
    Proc Natl Acad Sci U S A; 1996 Apr; 93(9):4001-5. PubMed ID: 8633005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatic cytochrome P-4503A (CYP3A) activity in the elderly.
    Hunt CM; Westerkam WR; Stave GM; Wilson JA
    Mech Ageing Dev; 1992 Jun; 64(1-2):189-99. PubMed ID: 1630156
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization.
    Chiou WL; Jeong HY; Wu TC; Ma C
    Clin Pharmacol Ther; 2001 Oct; 70(4):305-10. PubMed ID: 11673745
    [No Abstract]   [Full Text] [Related]  

  • 12. Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression.
    Berg-Candolfi M; Candolfi E; Benet LZ
    Xenobiotica; 1996 Apr; 26(4):381-94. PubMed ID: 9173679
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A.
    Kinirons MT; O'Shea D; Kim RB; Groopman JD; Thummel KE; Wood AJ; Wilkinson GR
    Clin Pharmacol Ther; 1999 Sep; 66(3):224-31. PubMed ID: 10511057
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Grapefruit juice activates P-glycoprotein-mediated drug transport.
    Soldner A; Christians U; Susanto M; Wacher VJ; Silverman JA; Benet LZ
    Pharm Res; 1999 Apr; 16(4):478-85. PubMed ID: 10227700
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel.
    Hendrikx JJ; Lagas JS; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
    Int J Cancer; 2013 May; 132(10):2439-47. PubMed ID: 23090875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity.
    McCrea J; Prueksaritanont T; Gertz BJ; Carides A; Gillen L; Antonello S; Brucker MJ; Miller-Stein C; Osborne B; Waldman S
    J Clin Pharmacol; 1999 Dec; 39(12):1212-20. PubMed ID: 10586386
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Measurement of hepatic and intestinal CYP3A4 and PGP activity by combined po + iv [14C]erythromycin breath and urine test.
    Lemahieu WP; Maes BD; Ghoos Y; Rutgeerts P; Verbeke K; Vanrenterghem Y
    Am J Physiol Gastrointest Liver Physiol; 2003 Sep; 285(3):G470-82. PubMed ID: 12909563
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats.
    Kageyama M; Namiki H; Fukushima H; Ito Y; Shibata N; Takada K
    Biol Pharm Bull; 2005 Feb; 28(2):316-22. PubMed ID: 15684491
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of chronic administration of ritonavir on function of cytochrome P450 3A and P-glycoprotein in rats.
    Kageyama M; Namiki H; Fukushima H; Terasaka S; Togawa T; Tanaka A; Ito Y; Shibata N; Takada K
    Biol Pharm Bull; 2005 Jan; 28(1):130-7. PubMed ID: 15635177
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.
    Perloff MD; von Moltke LL; Cotreau MM; Greenblatt DJ
    Biochem Pharmacol; 1999 Jun; 57(11):1227-32. PubMed ID: 10230766
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.